Group: paint - Dataset: paint_sgd
SUMMARY
This report generated on 2025-10-11
- Associations: 15553
- Lines in file (incl headers): 15579
- Lines skipped: 20
!gaf-version: 2.2
!Created on Wed Oct  1 17:41:08 2025.
!generated-by: PANTHER
!date-generated: 2025-10-01
!PANTHER version: v.19.0.
!GO version: 2025-07-22.  
Contents
gorule-0000002
gorule-0000005
gorule-0000006
gorule-0000007
gorule-0000008
gorule-0000011
gorule-0000013
gorule-0000015
gorule-0000016
gorule-0000017
gorule-0000018
gorule-0000020
gorule-0000022
gorule-0000027
gorule-0000028
gorule-0000029
gorule-0000030
gorule-0000037
gorule-0000039
gorule-0000042
gorule-0000043
gorule-0000046
gorule-0000050
gorule-0000055
gorule-0000058
gorule-0000061
gorule-0000063
gorule-0000064
gorule-0000065
other
MESSAGES
gorule-0000002
No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515'
gorule-0000005
IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''
gorule-0000006
IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC
gorule-0000007
IPI should not be used with GO:0003824 catalytic activity or descendents
gorule-0000008
No annotations should be made to uninformative high level terms
Messages
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000003615  PRY1    involved_in GO:0019953  GO_REF:0000033  IBA PANTHER:PTN000036124|FB:FBgn0037650|MGI:MGI:1916536|FB:FBgn0035042|FB:FBgn0054002|FB:FBgn0031412    P   Protein PRY1    UniProtKB:P47032|PTN000036722   protein taxon:559292    20250902    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000004160  APS1    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000204281|dictyBase:DDB_G0289721|RGD:1311115|SGD:S000004160|TAIR:locus:2051905|MGI:MGI:2141861|SGD:S000003819|PomBase:SPAP27G11.06c|UniProtKB:P56377|FB:FBgn0043012|UniProtKB:P61966|FB:FBgn0039132|RGD:620188   C   AP-1 complex subunit sigma-1    UniProtKB:P35181|PTN000204440   protein taxon:559292    20250902    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000004250  LCB5    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000270644|FB:FBgn0052484|dictyBase:DDB_G0272522|TAIR:locus:6530298214|SGD:S000003590|UniProtKB:Q53H12|MGI:MGI:1316649|UniProtKB:Q9NYA1|TAIR:locus:2119642|SGD:S000005697|MGI:MGI:1861380|WB:WBGene00007918|SGD:S000004250|UniProtKB:Q9NRA0|RGD:620048    C   Sphingoid long chain base kinase 5  UniProtKB:Q06147|PTN000270715   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000005269  FIG4    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000127900|SGD:S000005269|RGD:1311375|UniProtKB:Q92562|TAIR:locus:2009477 C   Polyphosphoinositide phosphatase    UniProtKB:P42837|PTN000127990   protein taxon:559292    20250904    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000005697  LCB4    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000270644|FB:FBgn0052484|dictyBase:DDB_G0272522|TAIR:locus:6530298214|SGD:S000003590|UniProtKB:Q53H12|MGI:MGI:1316649|UniProtKB:Q9NYA1|TAIR:locus:2119642|SGD:S000005697|MGI:MGI:1861380|WB:WBGene00007918|SGD:S000004250|UniProtKB:Q9NRA0|RGD:620048    C   Sphingoid long chain base kinase 4  UniProtKB:Q12246|PTN000270714   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000006315  DBF20   involved_in GO:0000910  GO_REF:0000033  IBA PANTHER:PTN008614896|dictyBase:DDB_G0284839|PomBase:SPAC24B11.11c|SGD:S000006315    P   Serine_threonine-protein kinase DBF20   UniProtKB:P32328|PTN000683463   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000002974  PMC1    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000642960|UniProtKB:P23634|TAIR:locus:2120096|SGD:S000002974|UniProtKB:P20020|PomBase:SPAPB2B4.04c|TAIR:locus:2082528|MGI:MGI:104653|MGI:MGI:105368|UniProtKB:Q57VN6|dictyBase:DDB_G0277861|TAIR:locus:2029794|TAIR:locus:2062673    C   Calcium-transporting ATPase 2   UniProtKB:P38929|PTN000643944   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000001876  LPD1    involved_in GO:0006090  GO_REF:0000033  IBA PANTHER:PTN000530299|RGD:735073|UniProtKB:Q8IAZ6|UniProtKB:P09622|MGI:MGI:107450    P   Dihydrolipoyl dehydrogenase, mitochondrial  UniProtKB:P09624|PTN000530350   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000007251  HUB1    involved_in GO:0036211  GO_REF:0000033  IBA PANTHER:PTN000315756|SGD:S000007251 P   Ubiquitin-like modifier HUB1    UniProtKB:Q6Q546|PTN000315803   protein taxon:559292    20240205    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000005938  IRC15   involved_in GO:0006090  GO_REF:0000033  IBA PANTHER:PTN000530299|RGD:735073|UniProtKB:Q8IAZ6|UniProtKB:P09622|MGI:MGI:107450    P   Increased recombination centers protein 15  UniProtKB:Q02733|PTN000530349   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000003614  PRY3    involved_in GO:0019953  GO_REF:0000033  IBA PANTHER:PTN000036124|FB:FBgn0037650|MGI:MGI:1916536|FB:FBgn0035042|FB:FBgn0054002|FB:FBgn0031412    P   Cell wall protein PRY3  UniProtKB:P47033|PTN002232859   protein taxon:559292    20250902    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000001721  PRY2    involved_in GO:0019953  GO_REF:0000033  IBA PANTHER:PTN000036124|FB:FBgn0037650|MGI:MGI:1916536|FB:FBgn0035042|FB:FBgn0054002|FB:FBgn0031412    P   Protein PRY2    UniProtKB:P36110|PTN000036720   protein taxon:559292    20250902    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000003561  APS3    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000204281|dictyBase:DDB_G0289721|RGD:1311115|SGD:S000004160|TAIR:locus:2051905|MGI:MGI:2141861|SGD:S000003819|PomBase:SPAP27G11.06c|UniProtKB:P56377|FB:FBgn0043012|UniProtKB:P61966|FB:FBgn0039132|RGD:620188   C   AP-3 complex subunit sigma  UniProtKB:P47064|PTN000204531   protein taxon:559292    20250902    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000003324  DBF2    involved_in GO:0000910  GO_REF:0000033  IBA PANTHER:PTN008614896|dictyBase:DDB_G0284839|PomBase:SPAC24B11.11c|SGD:S000006315    P   Cell cycle protein kinase DBF2  UniProtKB:P22204|PTN000683464   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000004572  MDM1    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000512111|MGI:MGI:2142610|UniProtKB:Q9Y5W7|MGI:MGI:1921581|UniProtKB:Q9Y5W8|FB:FBgn0029976   C   Structural protein MDM1 UniProtKB:Q01846|PTN000512247   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000001126  STE12   involved_in GO:0019953  GO_REF:0000033  IBA PANTHER:PTN001026538|UniProtKB:O74252|SGD:S000001126    P   Protein STE12   UniProtKB:P13574|PTN001427574   protein taxon:559292    20180419    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000003819  APS2    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000204281|dictyBase:DDB_G0289721|RGD:1311115|SGD:S000004160|TAIR:locus:2051905|MGI:MGI:2141861|SGD:S000003819|PomBase:SPAP27G11.06c|UniProtKB:P56377|FB:FBgn0043012|UniProtKB:P61966|FB:FBgn0039132|RGD:620188   C   AP-2 complex subunit sigma  UniProtKB:Q00381|PTN000204319   protein taxon:559292    20250902    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000004206  CPR6    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN002253524|UniProtKB:Q13427|dictyBase:DDB_G0269120|FB:FBgn0039581|WB:WBGene00000884|RGD:620315|dictyBase:DDB_G0280401|UniProtKB:Q9UNP9    C   Peptidyl-prolyl cis-trans isomerase CPR6    UniProtKB:P53691|PTN000116523   protein taxon:559292    20240918    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000005055  CYB5    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000451724|RGD:620558|RGD:621551|UniProtKB:Q385A5|UniProtKB:Q382H2|SGD:S000005055|UniProtKB:Q8I599|MGI:MGI:1926952|TAIR:locus:2028721 C   Cytochrome b5   UniProtKB:P40312|PTN000451738   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000000209  RCR1    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN002000118|SGD:S000002410|SGD:S000000209  C   Protein RCR1    UniProtKB:P38212|PTN002000125   protein taxon:559292    20230111    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000001512  MAE1    involved_in GO:0006090  GO_REF:0000033  IBA PANTHER:PTN000601050|UniProtKB:Q16798   P   NAD-dependent malic enzyme, mitochondrial   UniProtKB:P36013|PTN000601159   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000002781  FRQ1    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN001128334|PomBase:SPAC18B11.04|SGD:S000002781    C   Calcium-binding protein NCS-1   UniProtKB:Q06389|PTN000550929   protein taxon:559292    20240206    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000002410  RCR2    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN002000118|SGD:S000002410|SGD:S000000209  C   Protein RCR2    UniProtKB:Q03446|PTN002000126   protein taxon:559292    20230111    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000002728  SWA2    is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000571055|UniProtKB:Q27974|UniProtKB:O14976|SGD:S000002728   C   Auxilin-like clathrin uncoating factor SWA2 UniProtKB:Q06677|PTN000571123   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000003590  TIM54   is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000270644|FB:FBgn0052484|dictyBase:DDB_G0272522|TAIR:locus:6530298214|SGD:S000003590|UniProtKB:Q53H12|MGI:MGI:1316649|UniProtKB:Q9NYA1|TAIR:locus:2119642|SGD:S000005697|MGI:MGI:1861380|WB:WBGene00007918|SGD:S000004250|UniProtKB:Q9NRA0|RGD:620048    C   Mitochondrial import inner membrane translocase subunit TIM54   UniProtKB:P47045|PTN000961586   protein taxon:559292    20250903    GO_Central
- WARNING - Violates GO Rule: GORULE:0000008: No annotations should be made to uninformatively high level terms -- SGD S000004055  ENV10   is_active_in    GO:0043231  GO_REF:0000033  IBA PANTHER:PTN000337666|UniProtKB:Q9BTX3|UniProtKB:Q38FE8|FB:FBgn0034059   C   SRP-independent targeting protein 2 UniProtKB:Q99382|PTN000337710   protein taxon:559292    20250903    GO_Central
gorule-0000011
ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND
gorule-0000013
Taxon-appropriate annotation check
Messages
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000003034  SGF73   involved_in GO:0031048  GO_REF:0000033  IBA PANTHER:PTN001031589|PomBase:SPCC126.04c    P   SAGA-associated factor 73   UniProtKB:P53165|PTN000387891   protein taxon:559292    20240213    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000004715  MYO5    is_active_in    GO:0005902  GO_REF:0000033  IBA PANTHER:PTN001406997|UniProtKB:P47807|UniProtKB:Q9UBC5|UniProtKB:O00159|MGI:MGI:1927091|MGI:MGI:107732  C   Myosin-5    UniProtKB:Q04439|PTN000321837   protein taxon:559292    20240205    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000000257  YBR053C involved_in GO:0019853  GO_REF:0000033  IBA PANTHER:PTN000097355|MGI:MGI:108024 P   Uncharacterized protein YBR053C UniProtKB:P38235|PTN001656385   protein taxon:559292    20170228    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000000514  STP22   involved_in GO:0008333  GO_REF:0000033  IBA PANTHER:PTN000592420|WB:WBGene00015658|RGD:3909 P   Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease   UniProtKB:P25604|PTN000592498   protein taxon:559292    20211108    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000000641  RRT12   is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN002465725|RGD:728909|UniProtKB:Q8NBP7|MGI:MGI:2140260    C   Subtilase-type proteinase RRT12 UniProtKB:P25381|PTN000083480   protein taxon:559292    20181004    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000003615  PRY1    is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN000036124|MGI:MGI:1921366|FB:FBgn0250842|UniProtKB:A5D8T8    C   Protein PRY1    UniProtKB:P47032|PTN000036722   protein taxon:559292    20170512    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000005072  TEP1    involved_in GO:0048870  GO_REF:0000033  IBA PANTHER:PTN000959472|MGI:MGI:109583|dictyBase:DDB_G0286557  P   Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1    UniProtKB:P53916|PTN000266993   protein taxon:559292    20200305    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000001174  ECM14   is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN000194073|UniProtKB:P15085|UniProtKB:Q9UI42|RGD:71035    C   Inactive metallocarboxypeptidase ECM14  UniProtKB:P38836|PTN000194408   protein taxon:559292    20240729    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000003930  LMO1    involved_in GO:0048870  GO_REF:0000033  IBA PANTHER:PTN000299186|WB:WBGene00000426|UniProtKB:Q96JJ3|UniProtKB:Q92556|FB:FBgn0032409|dictyBase:DDB_G0278051  P   ELMO family protein LMO1    UniProtKB:Q07799|PTN001764799   protein taxon:559292    20221007    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000000786  PRB1    is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN002465725|RGD:728909|UniProtKB:Q8NBP7|MGI:MGI:2140260    C   Cerevisin   UniProtKB:P09232|PTN000083485   protein taxon:559292    20181004    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000003614  PRY3    is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN000036124|MGI:MGI:1921366|FB:FBgn0250842|UniProtKB:A5D8T8    C   Cell wall protein PRY3  UniProtKB:P47033|PTN002232859   protein taxon:559292    20170512    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000001721  PRY2    is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN000036124|MGI:MGI:1921366|FB:FBgn0250842|UniProtKB:A5D8T8    C   Protein PRY2    UniProtKB:P36110|PTN000036720   protein taxon:559292    20170512    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000004460  YPT7    is_active_in    GO:0045335  GO_REF:0000033  IBA PANTHER:PTN000635769|UniProtKB:P51151|FB:FBgn0015795|MGI:MGI:2442295|UniProtKB:P51149|UniProtKB:Q9NP90|WB:WBGene00004271|dictyBase:DDB_G0269236|UniProtKB:Q96AH8    C   Ypt_Rab-type GTPase YPT7    UniProtKB:P32939|PTN000635835   protein taxon:559292    20250413    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000003668  YJL132W is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN000576507|UniProtKB:P80108|MGI:MGI:106604|UniProtKB:P80109|RGD:631371    C   Uncharacterized protein YJL132W UniProtKB:P47014|PTN000576534   protein taxon:559292    20240206    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000002450  NRG1    part_of GO:0031519  GO_REF:0000033  IBA PANTHER:PTN000360827|MGI:MGI:99150|FB:FBgn0002521   C   Transcriptional regulator NRG1  UniProtKB:Q03125|PTN000149122   protein taxon:559292    20170602    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000001612  MYO3    is_active_in    GO:0005902  GO_REF:0000033  IBA PANTHER:PTN001406997|UniProtKB:P47807|UniProtKB:Q9UBC5|UniProtKB:O00159|MGI:MGI:1927091|MGI:MGI:107732  C   Myosin-3    UniProtKB:P36006|PTN000321838   protein taxon:559292    20240205    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000000270  NRG2    part_of GO:0031519  GO_REF:0000033  IBA PANTHER:PTN000360827|MGI:MGI:99150|FB:FBgn0002521   C   Probable transcriptional regulator NRG2 UniProtKB:P38082|PTN000360882   protein taxon:559292    20170602    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000003991  YLR001C is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN000096378|UniProtKB:Q15582|MGI:MGI:99959|RGD:1305285 C   FAS1 domain-containing protein YLR001C  UniProtKB:Q07895|PTN000096466   protein taxon:559292    20170228    GO_Central
- ERROR - Violates GO Rule: GORULE:0000013: Taxon-appropriate annotation check -- SGD  S000005529  YSP3    is_active_in    GO:0005615  GO_REF:0000033  IBA PANTHER:PTN002465725|RGD:728909|UniProtKB:Q8NBP7|MGI:MGI:2140260    C   Subtilisin-like protease 3  UniProtKB:P25036|PTN000083484   protein taxon:559292    20181004    GO_Central
gorule-0000015
Dual species taxon check
gorule-0000016
With/From: IC annotations require a With/From GO ID
gorule-0000017
IDA annotations must not have a With/From entry
gorule-0000018
IPI annotations require a With/From entry
gorule-0000020
Automatic repair of annotations to merged or obsoleted terms
Messages
- ERROR - Obsolete class with no replacement: Violates GORULE:0000020 (GO:0019933) -- SGD  S000005082  SRV2    involved_in GO:0019933  GO_REF:0000033  IBA PANTHER:PTN000068843|CGD:CAL0000183073  P   Adenylyl cyclase-associated protein UniProtKB:P17555|PTN000068919   protein taxon:559292    20210226    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000000206  RER2    involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN000815984|SGD:S000004707|SGD:S000000206  P   Dehydrodolichyl diphosphate synthase complex subunit RER2   UniProtKB:P35196|PTN000033374   protein taxon:559292    20180916    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000002213  PSA1    involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN000500861|ZFIN:ZDB-GENE-040801-234|SGD:S000002213    P   Mannose-1-phosphate guanyltransferase   UniProtKB:P41940|PTN000500912   protein taxon:559292    20210604    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000003822  YJR061W involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN001034988|MGI:MGI:2179507    P   Uncharacterized protein YJR061W UniProtKB:P40355|PTN001809790   protein taxon:559292    20250903    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000000178  ALG3    involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN000291297|SGD:S000000178|TAIR:locus:2043343  P   Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase  UniProtKB:P38179|PTN000291344   protein taxon:559292    20250903    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000004707  SRT1    involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN000815984|SGD:S000004707|SGD:S000000206  P   Dehydrodolichyl diphosphate synthase complex subunit SRT1   UniProtKB:Q03175|PTN000033371   protein taxon:559292    20180916    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000001684  MNN4    involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN001034988|MGI:MGI:2179507    P   Protein MNN4    UniProtKB:P36044|PTN000084394   protein taxon:559292    20250903    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000000314  ALG1    involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN000315506|TAIR:locus:2017963 P   Chitobiosyldiphosphodolichol beta-mannosyltransferase   UniProtKB:P16661|PTN000315553   protein taxon:559292    20250903    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006486) -- SGD  S000002352  NUS1    involved_in GO:0006486  GO_REF:0000033  IBA PANTHER:PTN000488276|SGD:S000002352 P   Dehydrodolichyl diphosphate synthase complex subunit NUS1   UniProtKB:Q12063|PTN000488311   protein taxon:559292    20250903    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006529) -- SGD  S000006349  ASN1    involved_in GO:0006529  GO_REF:0000033  IBA PANTHER:PTN000206334|RGD:2162|TAIR:locus:2099580|UniProtKB:P08243|SGD:S000003356|SGD:S000006349|PomBase:SPBC119.10|UniProtKB:P22106 P   Asparagine synthetase [glutamine-hydrolyzing] 1 UniProtKB:P49089|PTN000206465   protein taxon:559292    20250902    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0006529) -- SGD  S000003356  ASN2    involved_in GO:0006529  GO_REF:0000033  IBA PANTHER:PTN000206334|RGD:2162|TAIR:locus:2099580|UniProtKB:P08243|SGD:S000003356|SGD:S000006349|PomBase:SPBC119.10|UniProtKB:P22106 P   Asparagine synthetase [glutamine-hydrolyzing] 2 UniProtKB:P49090|PTN000206464   protein taxon:559292    20250902    GO_Central
- WARNING - Obsolete class: Violates GORULE:0000020, but was repaired (GO:0036456) -- SGD  S000000844  MXR1    enables GO:0036456  GO_REF:0000033  IBA PANTHER:PTN000019085|UniProtKB:P0A744|PomBase:SPAC29E6.05c  F   Peptide methionine sulfoxide reductase  UniProtKB:P40029|PTN000019309   protein taxon:559292    20181029    GO_Central
gorule-0000022
Check for, and filter, annotations made to retracted publications
gorule-0000027
Each identifier in GAF is valid
Messages
- WARNING - Invalid identifier: GORULE:0000027: 150342989 does not match any id_syntax patterns for RGD in dbxrefs (RGD:150342989) -- SGD  S000001375  SDP1    involved_in GO:0043409  GO_REF:0000033  IBA PANTHER:PTN001605855|RGD:70978|ZFIN:ZDB-GENE-040801-188|UniProtKB:P28562|MGI:MGI:2387107|dictyBase:DDB_G0269918|RGD:620897|UniProtKB:Q16829|MGI:MGI:105120|UniProtKB:Q9BY84|ZFIN:ZDB-GENE-030613-1|UniProtKB:Q16828|SGD:S000004998|WB:WBGene00006923|ZFIN:ZDB-GENE-040426-709|MGI:MGI:1927070|UniProtKB:Q9Y6W6|PomBase:SPBC1685.01|UniProtKB:Q13115|UniProtKB:Q91790|RGD:150342989|FB:FBgn0036844   P   Dual-specificity protein phosphatase SDP1   UniProtKB:P40479|PTN000017603   protein taxon:559292    20250902    GO_Central
- WARNING - Invalid identifier: GORULE:0000027: 150340783 does not match any id_syntax patterns for RGD in dbxrefs (RGD:150340783) -- SGD  S000006064  RPL33A  part_of GO:0022625  GO_REF:0000033  IBA PANTHER:PTN000096770|MGI:MGI:1928894|RGD:150340783|UniProtKB:P18077|SGD:S000005760|SGD:S000006064|PomBase:SPBC1921.01c|RGD:628793   C   Large ribosomal subunit protein eL33A   UniProtKB:P05744|PTN000096838   protein taxon:559292    20250902    GO_Central
- WARNING - Invalid identifier: GORULE:0000027: 150340783 does not match any id_syntax patterns for RGD in dbxrefs (RGD:150340783) -- SGD  S000005760  RPL33B  part_of GO:0022625  GO_REF:0000033  IBA PANTHER:PTN000096770|MGI:MGI:1928894|RGD:150340783|UniProtKB:P18077|SGD:S000005760|SGD:S000006064|PomBase:SPBC1921.01c|RGD:628793   C   Large ribosomal subunit protein eL33B   UniProtKB:P41056|PTN000096837   protein taxon:559292    20250902    GO_Central
- WARNING - Invalid identifier: GORULE:0000027: 150342989 does not match any id_syntax patterns for RGD in dbxrefs (RGD:150342989) -- SGD  S000004998  MSG5    involved_in GO:0043409  GO_REF:0000033  IBA PANTHER:PTN001605855|RGD:70978|ZFIN:ZDB-GENE-040801-188|UniProtKB:P28562|MGI:MGI:2387107|dictyBase:DDB_G0269918|RGD:620897|UniProtKB:Q16829|MGI:MGI:105120|UniProtKB:Q9BY84|ZFIN:ZDB-GENE-030613-1|UniProtKB:Q16828|SGD:S000004998|WB:WBGene00006923|ZFIN:ZDB-GENE-040426-709|MGI:MGI:1927070|UniProtKB:Q9Y6W6|PomBase:SPBC1685.01|UniProtKB:Q13115|UniProtKB:Q91790|RGD:150342989|FB:FBgn0036844   P   Tyrosine-protein phosphatase MSG5   UniProtKB:P38590|PTN000017604   protein taxon:559292    20250902    GO_Central
- WARNING - Invalid identifier: GORULE:0000027: 150342989 does not match any id_syntax patterns for RGD in dbxrefs (RGD:150342989) -- SGD  S000004998  MSG5    involved_in GO:0007165  GO_REF:0000033  IBA PANTHER:PTN004128558|RGD:620897|RGD:150342989|SGD:S000004998|WB:WBGene00003043|SGD:S000001375|FB:FBgn0243512    P   Tyrosine-protein phosphatase MSG5   UniProtKB:P38590|PTN000017604   protein taxon:559292    20250902    GO_Central
- WARNING - Invalid identifier: GORULE:0000027: 150342989 does not match any id_syntax patterns for RGD in dbxrefs (RGD:150342989) -- SGD  S000001375  SDP1    involved_in GO:0007165  GO_REF:0000033  IBA PANTHER:PTN004128558|RGD:620897|RGD:150342989|SGD:S000004998|WB:WBGene00003043|SGD:S000001375|FB:FBgn0243512    P   Dual-specificity protein phosphatase SDP1   UniProtKB:P40479|PTN000017603   protein taxon:559292    20250902    GO_Central
gorule-0000028
GO aspect should match the term's namespace; otherwise it is repaired to the appropriate aspect
gorule-0000029
IEAs should be less than one year old.
gorule-0000030
Obsolete GO_REFs are not allowed
gorule-0000037
IBA annotations should ONLY be assigned_by GO_Central and have GO_REF:0000033 as a reference
gorule-0000039
Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants
gorule-0000042
Qualifier: IKR evidence code requires a NOT qualifier
gorule-0000043
Check for valid combination of evidence code and GO_REF
gorule-0000046
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.
Messages
- WARNING - Violates GO Rule: GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms -- SGD  S000003863  VPS25   enables GO:0042803  GO_REF:0000033  IBA PANTHER:PTN000322234|UniProtKB:Q9BRG1   F   Vacuolar protein-sorting-associated protein 25  UniProtKB:P47142|PTN000322275   protein taxon:559292    20170228    GO_Central
gorule-0000050
Annotations to ISS, ISA and ISO should not be self-referential
gorule-0000055
References should have only one ID per ID space
gorule-0000058
Object extensions should conform to the extensions-patterns.yaml file in metadata
gorule-0000061
Allowed gene product to term relations (gp2term)
gorule-0000063
Annotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)
gorule-0000064
TreeGrafter IEAs should be filtered for GO reference species
gorule-0000065
Annotations to term that are candidates for obsoletion should be produce a warning
other
 
GO:1904668	positive regulation of ubiquitin protein ligase activity	AnnotationPropagation	P	GO:1990757	ubiquitin ligase activator activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0035350	FAD transmembrane transport	AnnotationPropagation	P	GO:0015230	FAD transmembrane transporter activity	IBA
GO:0005783	endoplasmic reticulum	AnnotationPropagation	C	GO:0006621	protein retention in ER lumen	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0061025	membrane fusion	AnnotationPropagation	P	GO:0005484	SNAP receptor activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0015385	sodium:proton antiporter activity	IBA
GO:0035725	sodium ion transmembrane transport	AnnotationPropagation	P	GO:0015385	sodium:proton antiporter activity	IBA
GO:0042780	tRNA 3'-end processing	AnnotationPropagation	P	GO:0042781	3'-tRNA processing endoribonuclease activity	IBA
GO:0015914	phospholipid transport	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0120009	intermembrane lipid transfer	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0005773	vacuole	AnnotationPropagation	C	GO:0007039	protein catabolic process in the vacuole	IBA
GO:0006222	UMP biosynthetic process	AnnotationPropagation	P	GO:0004849	uridine kinase activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0030970	retrograde protein transport, ER to cytosol	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0032527	protein exit from endoplasmic reticulum	IBA
GO:0005829	cytosol	AnnotationPropagation	C	GO:0006895	Golgi to endosome transport	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0034551	mitochondrial respiratory chain complex III assembly	IBA
GO:0019430	removal of superoxide radicals	AnnotationPropagation	P	GO:0004784	superoxide dismutase activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0046513	ceramide biosynthetic process	IBA
GO:0072488	ammonium transmembrane transport	AnnotationPropagation	P	GO:0008519	ammonium channel activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0000165	MAPK cascade	AnnotationPropagation	P	GO:0004708	MAP kinase kinase activity	IBA
GO:0006414	translational elongation	AnnotationPropagation	P	GO:0003746	translation elongation factor activity	IBA
GO:0099116	tRNA 5'-end processing	AnnotationPropagation	P	GO:0008193	tRNA guanylyltransferase activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	IBA
GO:1901679	nucleotide transmembrane transport	AnnotationPropagation	P	GO:0015218	pyrimidine nucleotide transmembrane transporter activity	IBA
GO:0006864	pyrimidine nucleotide transport	AnnotationPropagation	P	GO:0015218	pyrimidine nucleotide transmembrane transporter activity	IBA
GO:0006413	translational initiation	AnnotationPropagation	P	GO:0003743	translation initiation factor activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0042800	histone H3K4 methyltransferase activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0045944	positive regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0046513	ceramide biosynthetic process	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0010485	histone H4 acetyltransferase activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0045039	protein insertion into mitochondrial inner membrane	IBA
GO:0005829	cytosol	AnnotationPropagation	C	GO:0042147	retrograde transport, endosome to Golgi	IBA
GO:1902475	L-alpha-amino acid transmembrane transport	AnnotationPropagation	P	GO:0015179	L-amino acid transmembrane transporter activity	IBA
GO:0046835	carbohydrate phosphorylation	AnnotationPropagation	P	GO:0019158	mannokinase activity	IBA
GO:0005829	cytosol	AnnotationPropagation	C	GO:0006895	Golgi to endosome transport	IBA
GO:1901679	nucleotide transmembrane transport	AnnotationPropagation	P	GO:0015215	nucleotide transmembrane transporter activity	IBA
GO:0033214	siderophore-iron import into cell	AnnotationPropagation	P	GO:0015343	siderophore-iron transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0015343	siderophore-iron transmembrane transporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0004407	histone deacetylase activity	IBA
GO:0015909	long-chain fatty acid transport	AnnotationPropagation	P	GO:0005324	long-chain fatty acid transmembrane transporter activity	IBA
GO:1905039	carboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0005324	long-chain fatty acid transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0046972	histone H4K16 acetyltransferase activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0000957	mitochondrial RNA catabolic process	IBA
GO:0006415	translational termination	AnnotationPropagation	P	GO:0016149	translation release factor activity, codon specific	IBA
GO:0035433	acetate transmembrane transport	AnnotationPropagation	P	GO:0015123	acetate transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0034553	mitochondrial respiratory chain complex II assembly	IBA
GO:0006414	translational elongation	AnnotationPropagation	P	GO:0003746	translation elongation factor activity	IBA
GO:0035442	dipeptide transmembrane transport	AnnotationPropagation	P	GO:0071916	dipeptide transmembrane transporter activity	IBA
GO:0000226	microtubule cytoskeleton organization	AnnotationPropagation	P	GO:0008568	microtubule severing ATPase activity	IBA
GO:1901475	pyruvate transmembrane transport	AnnotationPropagation	P	GO:0050833	pyruvate transmembrane transporter activity	IBA
GO:0071934	thiamine transmembrane transport	AnnotationPropagation	P	GO:0015234	thiamine transmembrane transporter activity	IBA
GO:0031167	rRNA methylation	AnnotationPropagation	P	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	IBA
GO:0071806	protein transmembrane transport	AnnotationPropagation	P	GO:0008320	protein transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0005315	phosphate transmembrane transporter activity	IBA
GO:0015718	monocarboxylic acid transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0015812	gamma-aminobutyric acid transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:1905039	carboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0045893	positive regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003713	transcription coactivator activity	IBA
GO:0022904	respiratory electron transport chain	AnnotationPropagation	P	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity	IBA
GO:0006414	translational elongation	AnnotationPropagation	P	GO:0003746	translation elongation factor activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0070154	mitochondrial lysyl-tRNA aminoacylation	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0015706	nitrate transmembrane transport	AnnotationPropagation	P	GO:0015513	high-affinity secondary active nitrite transmembrane transporter activity	IBA
GO:0006413	translational initiation	AnnotationPropagation	P	GO:0004479	methionyl-tRNA formyltransferase activity	IBA
GO:0071951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	AnnotationPropagation	P	GO:0004479	methionyl-tRNA formyltransferase activity	IBA
GO:1901475	pyruvate transmembrane transport	AnnotationPropagation	P	GO:0050833	pyruvate transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0006366	transcription by RNA polymerase II	AnnotationPropagation	P	GO:0016251	RNA polymerase II general transcription initiation factor activity	IBA
GO:0045893	positive regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003713	transcription coactivator activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0045039	protein insertion into mitochondrial inner membrane	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	IBA
GO:0071806	protein transmembrane transport	AnnotationPropagation	P	GO:0008320	protein transmembrane transporter activity	IBA
GO:0015746	citrate transport	AnnotationPropagation	P	GO:0071913	citrate secondary active transmembrane transporter activity	IBA
GO:0035674	tricarboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0071913	citrate secondary active transmembrane transporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0002943	tRNA dihydrouridine synthesis	AnnotationPropagation	P	GO:0017150	tRNA dihydrouridine synthase activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0006355	regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003700	DNA-binding transcription factor activity	IBA
GO:0015791	polyol transmembrane transport	AnnotationPropagation	P	GO:0005366	myo-inositol:proton symporter activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005366	myo-inositol:proton symporter activity	IBA
GO:0015798	myo-inositol transport	AnnotationPropagation	P	GO:0005366	myo-inositol:proton symporter activity	IBA
GO:0046835	carbohydrate phosphorylation	AnnotationPropagation	P	GO:0004340	glucokinase activity	IBA
GO:0051156	glucose 6-phosphate metabolic process	AnnotationPropagation	P	GO:0004340	glucokinase activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0004407	histone deacetylase activity	IBA
GO:0098655	monoatomic cation transmembrane transport	AnnotationPropagation	P	GO:0005227	calcium-activated cation channel activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0140359	ABC-type transporter activity	IBA
GO:0006414	translational elongation	AnnotationPropagation	P	GO:0003746	translation elongation factor activity	IBA
GO:0006259	DNA metabolic process	AnnotationPropagation	P	GO:0008296	3'-5'-DNA exonuclease activity	IBA
GO:0035269	protein O-linked glycosylation via mannose	AnnotationPropagation	P	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity	IBA
GO:0006259	DNA metabolic process	AnnotationPropagation	P	GO:0004520	DNA endonuclease activity	IBA
GO:0089722	phosphoenolpyruvate transmembrane transport	AnnotationPropagation	P	GO:0089721	phosphoenolpyruvate transmembrane transporter activity	IBA
GO:0015828	tyrosine transport	AnnotationPropagation	P	GO:0005302	L-tyrosine transmembrane transporter activity	IBA
GO:1902475	L-alpha-amino acid transmembrane transport	AnnotationPropagation	P	GO:0005302	L-tyrosine transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0032979	protein insertion into mitochondrial inner membrane from matrix	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0008559	ABC-type xenobiotic transporter activity	IBA
GO:0042908	xenobiotic transport	AnnotationPropagation	P	GO:0008559	ABC-type xenobiotic transporter activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0090150	establishment of protein localization to membrane	AnnotationPropagation	P	GO:0032977	membrane insertase activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity	AnnotationPropagation	P	GO:0051500	D-tyrosyl-tRNA(Tyr) deacylase activity	IBA
GO:0022904	respiratory electron transport chain	AnnotationPropagation	P	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity	IBA
GO:1903711	spermidine transmembrane transport	AnnotationPropagation	P	GO:0015606	spermidine transmembrane transporter activity	IBA
GO:0006633	fatty acid biosynthetic process	AnnotationPropagation	P	GO:0000036	acyl carrier activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0051999	mannosyl-inositol phosphorylceramide biosynthetic process	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0046514	ceramide catabolic process	IBA
GO:0000165	MAPK cascade	AnnotationPropagation	P	GO:0004708	MAP kinase kinase activity	IBA
GO:0031167	rRNA methylation	AnnotationPropagation	P	GO:0008650	rRNA (uridine-2'-O-)-methyltransferase activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0006167	AMP biosynthetic process	AnnotationPropagation	P	GO:0004001	adenosine kinase activity	IBA
GO:0006913	nucleocytoplasmic transport	AnnotationPropagation	P	GO:0017056	structural constituent of nuclear pore	IBA
GO:0006366	transcription by RNA polymerase II	AnnotationPropagation	P	GO:0016251	RNA polymerase II general transcription initiation factor activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0032543	mitochondrial translation	IBA
GO:0007010	cytoskeleton organization	AnnotationPropagation	P	GO:0005200	structural constituent of cytoskeleton	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	IBA
GO:0033214	siderophore-iron import into cell	AnnotationPropagation	P	GO:0015343	siderophore-iron transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0015343	siderophore-iron transmembrane transporter activity	IBA
GO:1903710	spermine transmembrane transport	AnnotationPropagation	P	GO:0000297	spermine transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0032543	mitochondrial translation	IBA
GO:0045892	negative regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003714	transcription corepressor activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0006627	protein processing involved in protein targeting to mitochondrion	IBA
GO:0006414	translational elongation	AnnotationPropagation	P	GO:0003746	translation elongation factor activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0071805	potassium ion transmembrane transport	AnnotationPropagation	P	GO:0008556	P-type potassium transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0097250	mitochondrial respirasome assembly	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0005829	cytosol	AnnotationPropagation	C	GO:0042147	retrograde transport, endosome to Golgi	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0006413	translational initiation	AnnotationPropagation	P	GO:0003743	translation initiation factor activity	IBA
GO:0006259	DNA metabolic process	AnnotationPropagation	P	GO:0017108	5'-flap endonuclease activity	IBA
GO:0006414	translational elongation	AnnotationPropagation	P	GO:0003746	translation elongation factor activity	IBA
GO:0015816	glycine transport	AnnotationPropagation	P	GO:0015187	glycine transmembrane transporter activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015187	glycine transmembrane transporter activity	IBA
GO:1905039	carboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0015187	glycine transmembrane transporter activity	IBA
GO:0006310	DNA recombination	AnnotationPropagation	P	GO:0000150	DNA strand exchange activity	IBA
GO:0015914	phospholipid transport	AnnotationPropagation	P	GO:1990050	phosphatidic acid transfer activity	IBA
GO:0120009	intermembrane lipid transfer	AnnotationPropagation	P	GO:1990050	phosphatidic acid transfer activity	IBA
GO:0098869	cellular oxidant detoxification	AnnotationPropagation	P	GO:0008379	thioredoxin peroxidase activity	IBA
GO:0006744	ubiquinone biosynthetic process	AnnotationPropagation	P	GO:0120539	4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0045039	protein insertion into mitochondrial inner membrane	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0070158	mitochondrial seryl-tRNA aminoacylation	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0042054	histone methyltransferase activity	IBA
GO:0033214	siderophore-iron import into cell	AnnotationPropagation	P	GO:0015343	siderophore-iron transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0015343	siderophore-iron transmembrane transporter activity	IBA
GO:0098655	monoatomic cation transmembrane transport	AnnotationPropagation	P	GO:0005227	calcium-activated cation channel activity	IBA
GO:0005634	nucleus	AnnotationPropagation	C	GO:0071038	TRAMP-dependent tRNA surveillance pathway	IBA
GO:0015718	monocarboxylic acid transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0015812	gamma-aminobutyric acid transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:1905039	carboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0015876	acetyl-CoA transport	AnnotationPropagation	P	GO:0008521	acetyl-CoA transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0008521	acetyl-CoA transmembrane transporter activity	IBA
GO:1901962	S-adenosyl-L-methionine transmembrane transport	AnnotationPropagation	P	GO:0000095	S-adenosyl-L-methionine transmembrane transporter activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0098656	monoatomic anion transmembrane transport	AnnotationPropagation	P	GO:0008308	voltage-gated monoatomic anion channel activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0005315	phosphate transmembrane transporter activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015171	amino acid transmembrane transporter activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0030148	sphingolipid biosynthetic process	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0006417	regulation of translation	AnnotationPropagation	P	GO:0045182	translation regulator activity	IBA
GO:0006259	DNA metabolic process	AnnotationPropagation	P	GO:0008821	crossover junction DNA endonuclease activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0032979	protein insertion into mitochondrial inner membrane from matrix	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0030149	sphingolipid catabolic process	IBA
GO:0005773	vacuole	AnnotationPropagation	C	GO:0007039	protein catabolic process in the vacuole	IBA
GO:0002943	tRNA dihydrouridine synthesis	AnnotationPropagation	P	GO:0017150	tRNA dihydrouridine synthase activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0034551	mitochondrial respiratory chain complex III assembly	IBA
GO:0045944	positive regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0045944	positive regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA
GO:0006913	nucleocytoplasmic transport	AnnotationPropagation	P	GO:0017056	structural constituent of nuclear pore	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0070588	calcium ion transmembrane transport	AnnotationPropagation	P	GO:0005262	calcium channel activity	IBA
GO:0006457	protein folding	AnnotationPropagation	P	GO:0044183	protein folding chaperone	IBA
GO:1990570	GDP-mannose transmembrane transport	AnnotationPropagation	P	GO:0005458	GDP-mannose transmembrane transporter activity	IBA
GO:0071577	zinc ion transmembrane transport	AnnotationPropagation	P	GO:0000007	low-affinity zinc ion transmembrane transporter activity	IBA
GO:0035352	NAD transmembrane transport	AnnotationPropagation	P	GO:0051724	NAD transmembrane transporter activity	IBA
GO:0045893	positive regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003713	transcription coactivator activity	IBA
GO:0006413	translational initiation	AnnotationPropagation	P	GO:0003743	translation initiation factor activity	IBA
GO:0071805	potassium ion transmembrane transport	AnnotationPropagation	P	GO:0015079	potassium ion transmembrane transporter activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0098734	macromolecule depalmitoylation	AnnotationPropagation	P	GO:0008474	palmitoyl-(protein) hydrolase activity	IBA
GO:0098869	cellular oxidant detoxification	AnnotationPropagation	P	GO:0004601	peroxidase activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0015386	potassium:proton antiporter activity	IBA
GO:0071805	potassium ion transmembrane transport	AnnotationPropagation	P	GO:0015386	potassium:proton antiporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0032543	mitochondrial translation	IBA
GO:0006353	DNA-templated transcription termination	AnnotationPropagation	P	GO:0001147	transcription termination site sequence-specific DNA binding	IBA
GO:0006366	transcription by RNA polymerase II	AnnotationPropagation	P	GO:0016251	RNA polymerase II general transcription initiation factor activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0005634	nucleus	AnnotationPropagation	C	GO:0071031	nuclear mRNA surveillance of mRNA 3'-end processing	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0015205	nucleobase transmembrane transporter activity	IBA
GO:0015851	nucleobase transport	AnnotationPropagation	P	GO:0015205	nucleobase transmembrane transporter activity	IBA
GO:0006259	DNA metabolic process	AnnotationPropagation	P	GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	IBA
GO:0006355	regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003700	DNA-binding transcription factor activity	IBA
GO:1903826	L-arginine transmembrane transport	AnnotationPropagation	P	GO:0061459	L-arginine transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0098655	monoatomic cation transmembrane transport	AnnotationPropagation	P	GO:0005227	calcium-activated cation channel activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0046521	sphingoid catabolic process	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0001188	RNA polymerase I preinitiation complex assembly	AnnotationPropagation	P	GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0051999	mannosyl-inositol phosphorylceramide biosynthetic process	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0034551	mitochondrial respiratory chain complex III assembly	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0070159	mitochondrial threonyl-tRNA aminoacylation	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0034982	mitochondrial protein processing	IBA
GO:1903401	L-lysine transmembrane transport	AnnotationPropagation	P	GO:0015189	L-lysine transmembrane transporter activity	IBA
GO:1990822	basic amino acid transmembrane transport	AnnotationPropagation	P	GO:0015189	L-lysine transmembrane transporter activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015171	amino acid transmembrane transporter activity	IBA
GO:0042823	pyridoxal phosphate biosynthetic process	AnnotationPropagation	P	GO:0004733	pyridoxamine phosphate oxidase activity	IBA
GO:0006413	translational initiation	AnnotationPropagation	P	GO:0003743	translation initiation factor activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0015718	monocarboxylic acid transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0015812	gamma-aminobutyric acid transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:1905039	carboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity	IBA
GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	AnnotationPropagation	P	GO:0004326	tetrahydrofolylpolyglutamate synthase activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0015205	nucleobase transmembrane transporter activity	IBA
GO:0015851	nucleobase transport	AnnotationPropagation	P	GO:0015205	nucleobase transmembrane transporter activity	IBA
GO:0051170	import into nucleus	AnnotationPropagation	P	GO:0061608	nuclear import signal receptor activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	IBA
GO:0034204	lipid translocation	AnnotationPropagation	P	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IBA
GO:1903790	guanine nucleotide transmembrane transport	AnnotationPropagation	P	GO:0001409	guanine nucleotide transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0006833	water transport	AnnotationPropagation	P	GO:0015250	water channel activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0015250	water channel activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006673	inositol phosphoceramide metabolic process	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0045117	azole transmembrane transport	AnnotationPropagation	P	GO:0015244	fluconazole transmembrane transporter activity	IBA
GO:0015903	fluconazole transport	AnnotationPropagation	P	GO:0015244	fluconazole transmembrane transporter activity	IBA
GO:0005634	nucleus	AnnotationPropagation	C	GO:0071039	nuclear polyadenylation-dependent CUT catabolic process	IBA
GO:0046835	carbohydrate phosphorylation	AnnotationPropagation	P	GO:0003873	6-phosphofructo-2-kinase activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0005634	nucleus	AnnotationPropagation	C	GO:0071028	nuclear mRNA surveillance	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0010498	proteasomal protein catabolic process	AnnotationPropagation	P	GO:0036402	proteasome-activating activity	IBA
GO:0051168	nuclear export	AnnotationPropagation	P	GO:0005049	nuclear export signal receptor activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0035725	sodium ion transmembrane transport	AnnotationPropagation	P	GO:0005436	sodium:phosphate symporter activity	IBA
GO:0035672	oligopeptide transmembrane transport	AnnotationPropagation	P	GO:0035673	oligopeptide transmembrane transporter activity	IBA
GO:0006366	transcription by RNA polymerase II	AnnotationPropagation	P	GO:0016251	RNA polymerase II general transcription initiation factor activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0098734	macromolecule depalmitoylation	AnnotationPropagation	P	GO:0008474	palmitoyl-(protein) hydrolase activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0045040	protein insertion into mitochondrial outer membrane	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0006627	protein processing involved in protein targeting to mitochondrion	IBA
GO:0072488	ammonium transmembrane transport	AnnotationPropagation	P	GO:0008519	ammonium channel activity	IBA
GO:0015813	L-glutamate transmembrane transport	AnnotationPropagation	P	GO:0005313	L-glutamate transmembrane transporter activity	IBA
GO:0015741	fumarate transport	AnnotationPropagation	P	GO:0005469	succinate:fumarate antiporter activity	IBA
GO:0071422	succinate transmembrane transport	AnnotationPropagation	P	GO:0005469	succinate:fumarate antiporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0007007	inner mitochondrial membrane organization	IBA
GO:0098656	monoatomic anion transmembrane transport	AnnotationPropagation	P	GO:0008308	voltage-gated monoatomic anion channel activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0042407	cristae formation	IBA
GO:0045892	negative regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003714	transcription corepressor activity	IBA
GO:1901679	nucleotide transmembrane transport	AnnotationPropagation	P	GO:0015217	ADP transmembrane transporter activity	IBA
GO:0015866	ADP transport	AnnotationPropagation	P	GO:0015217	ADP transmembrane transporter activity	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0140750	nucleosome array spacer activity	IBA
GO:0035672	oligopeptide transmembrane transport	AnnotationPropagation	P	GO:0035673	oligopeptide transmembrane transporter activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0006457	protein folding	AnnotationPropagation	P	GO:0044183	protein folding chaperone	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0006259	DNA metabolic process	AnnotationPropagation	P	GO:0017108	5'-flap endonuclease activity	IBA
GO:0051170	import into nucleus	AnnotationPropagation	P	GO:0061608	nuclear import signal receptor activity	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA
GO:0034755	iron ion transmembrane transport	AnnotationPropagation	P	GO:0015093	ferrous iron transmembrane transporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0030148	sphingolipid biosynthetic process	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0015816	glycine transport	AnnotationPropagation	P	GO:0015187	glycine transmembrane transporter activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015187	glycine transmembrane transporter activity	IBA
GO:1905039	carboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0015187	glycine transmembrane transporter activity	IBA
GO:0005829	cytosol	AnnotationPropagation	C	GO:0006895	Golgi to endosome transport	IBA
GO:0015914	phospholipid transport	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0120009	intermembrane lipid transfer	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0005794	Golgi apparatus	AnnotationPropagation	C	GO:0032468	Golgi calcium ion homeostasis	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	IBA
GO:0061025	membrane fusion	AnnotationPropagation	P	GO:0005484	SNAP receptor activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0140359	ABC-type transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA
GO:0006338	chromatin remodeling	AnnotationPropagation	P	GO:0032454	histone H3K9 demethylase activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0005829	cytosol	AnnotationPropagation	C	GO:0006895	Golgi to endosome transport	IBA
GO:0070588	calcium ion transmembrane transport	AnnotationPropagation	P	GO:0005388	P-type calcium transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0140359	ABC-type transporter activity	IBA
GO:0015793	glycerol transmembrane transport	AnnotationPropagation	P	GO:0015254	glycerol channel activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0045039	protein insertion into mitochondrial inner membrane	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA
GO:0098869	cellular oxidant detoxification	AnnotationPropagation	P	GO:0032542	sulfiredoxin activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015171	amino acid transmembrane transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0045892	negative regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003714	transcription corepressor activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0006627	protein processing involved in protein targeting to mitochondrion	IBA
GO:0006457	protein folding	AnnotationPropagation	P	GO:0044183	protein folding chaperone	IBA
GO:0071805	potassium ion transmembrane transport	AnnotationPropagation	P	GO:0015271	outward rectifier potassium channel activity	IBA
GO:0005634	nucleus	AnnotationPropagation	C	GO:0033621	nuclear mRNA surveillance of meiosis-specific transcripts	IBA
GO:0006591	ornithine metabolic process	AnnotationPropagation	P	GO:0004585	ornithine carbamoyltransferase activity	IBA
GO:0005773	vacuole	AnnotationPropagation	C	GO:0007039	protein catabolic process in the vacuole	IBA
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	AnnotationPropagation	P	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	IBA
GO:0003333	amino acid transmembrane transport	AnnotationPropagation	P	GO:0015171	amino acid transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0032543	mitochondrial translation	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0071577	zinc ion transmembrane transport	AnnotationPropagation	P	GO:0005385	zinc ion transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0000965	mitochondrial RNA 3'-end processing	IBA
GO:0034755	iron ion transmembrane transport	AnnotationPropagation	P	GO:0015093	ferrous iron transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0016192	vesicle-mediated transport	AnnotationPropagation	P	GO:0140312	cargo adaptor activity	IBA
GO:0000160	phosphorelay signal transduction system	AnnotationPropagation	P	GO:0000156	phosphorelay response regulator activity	IBA
GO:0015790	UDP-xylose transmembrane transport	AnnotationPropagation	P	GO:0005464	UDP-xylose transmembrane transporter activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0000165	MAPK cascade	AnnotationPropagation	P	GO:0004707	MAP kinase activity	IBA
GO:0071805	potassium ion transmembrane transport	AnnotationPropagation	P	GO:0015079	potassium ion transmembrane transporter activity	IBA
GO:0035433	acetate transmembrane transport	AnnotationPropagation	P	GO:0015123	acetate transmembrane transporter activity	IBA
GO:0006357	regulation of transcription by RNA polymerase II	AnnotationPropagation	P	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0015914	phospholipid transport	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0120009	intermembrane lipid transfer	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0070588	calcium ion transmembrane transport	AnnotationPropagation	P	GO:0005262	calcium channel activity	IBA
GO:0051170	import into nucleus	AnnotationPropagation	P	GO:0061608	nuclear import signal receptor activity	IBA
GO:0015828	tyrosine transport	AnnotationPropagation	P	GO:0005302	L-tyrosine transmembrane transporter activity	IBA
GO:1902475	L-alpha-amino acid transmembrane transport	AnnotationPropagation	P	GO:0005302	L-tyrosine transmembrane transporter activity	IBA
GO:0002943	tRNA dihydrouridine synthesis	AnnotationPropagation	P	GO:0017150	tRNA dihydrouridine synthase activity	IBA
GO:0015914	phospholipid transport	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0120009	intermembrane lipid transfer	AnnotationPropagation	P	GO:0008526	phosphatidylinositol transfer activity	IBA
GO:0006414	translational elongation	AnnotationPropagation	P	GO:0003746	translation elongation factor activity	IBA
GO:0005829	cytosol	AnnotationPropagation	C	GO:0042147	retrograde transport, endosome to Golgi	IBA
GO:1905039	carboxylic acid transmembrane transport	AnnotationPropagation	P	GO:0046943	carboxylic acid transmembrane transporter activity	IBA
GO:0000781	chromosome, telomeric region	AnnotationPropagation	C	GO:0031509	subtelomeric heterochromatin formation	IBA
GO:0006913	nucleocytoplasmic transport	AnnotationPropagation	P	GO:0017056	structural constituent of nuclear pore	IBA
GO:0046940	nucleoside monophosphate phosphorylation	AnnotationPropagation	P	GO:0004017	AMP kinase activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0140359	ABC-type transporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0022857	transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0034553	mitochondrial respiratory chain complex II assembly	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0006390	mitochondrial transcription	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0033617	mitochondrial respiratory chain complex IV assembly	IBA
GO:0051170	import into nucleus	AnnotationPropagation	P	GO:0061608	nuclear import signal receptor activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0017121	plasma membrane phospholipid scrambling	AnnotationPropagation	P	GO:0017128	phospholipid scramblase activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0045039	protein insertion into mitochondrial inner membrane	IBA
GO:0006366	transcription by RNA polymerase II	AnnotationPropagation	P	GO:0016251	RNA polymerase II general transcription initiation factor activity	IBA
GO:0097359	UDP-glucosylation	AnnotationPropagation	P	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity	IBA
GO:0098869	cellular oxidant detoxification	AnnotationPropagation	P	GO:0008379	thioredoxin peroxidase activity	IBA
GO:0016020	membrane	AnnotationPropagation	C	GO:0006506	GPI anchor biosynthetic process	IBA
GO:0106005	RNA 5'-cap (guanine-N7)-methylation	AnnotationPropagation	P	GO:0004482	mRNA 5'-cap (guanine-N7-)-methyltransferase activity	IBA
GO:0006370	7-methylguanosine mRNA capping	AnnotationPropagation	P	GO:0004482	mRNA 5'-cap (guanine-N7-)-methyltransferase activity	IBA
GO:0042823	pyridoxal phosphate biosynthetic process	AnnotationPropagation	P	GO:0004733	pyridoxamine phosphate oxidase activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0042776	proton motive force-driven mitochondrial ATP synthesis	IBA
GO:1903401	L-lysine transmembrane transport	AnnotationPropagation	P	GO:0015189	L-lysine transmembrane transporter activity	IBA
GO:1990822	basic amino acid transmembrane transport	AnnotationPropagation	P	GO:0015189	L-lysine transmembrane transporter activity	IBA
GO:0005739	mitochondrion	AnnotationPropagation	C	GO:0045040	protein insertion into mitochondrial outer membrane	IBA
GO:0031167	rRNA methylation	AnnotationPropagation	P	GO:0016435	rRNA (guanine) methyltransferase activity	IBA
GO:0005634	nucleus	AnnotationPropagation	C	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	IBA
GO:0005737	cytoplasm	AnnotationPropagation	C	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	IBA
GO:0006355	regulation of DNA-templated transcription	AnnotationPropagation	P	GO:0003700	DNA-binding transcription factor activity	IBA
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	AnnotationPropagation	P	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	IBA
GO:1902600	proton transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0034219	carbohydrate transmembrane transport	AnnotationPropagation	P	GO:0005351	carbohydrate:proton symporter activity	IBA
GO:0055085	transmembrane transport	AnnotationPropagation	P	GO:0015297	antiporter activity	IBA