Table of contents

Report

Group: mgi - Dataset: mgi

SUMMARY

This report generated on 2020-03-27

Header From Original Association File

!gaf-version: 2.1
!software version: $Revision$
!date: 03/27/2020 $
!
! from Mouse Genome Database (MGD) & Gene Expression Database (GXD)
!
! 1. DB MGI
! 2. DB Object ID MGI:xxxx
! 3. DB Object Symbol
! 4. Qualifier
! 5. GO ID GO:xxxx
! 6. DB:Reference(s) MGI:MGI:xxxx|PMID:xxxx
! 7. Evidence Code 3-digit (not ECO:xxxx)
! 8. With (or)From optional
! 9. Aspect (GO DAG Abbreviation (F, P, C))
! 10. DB Object Name optional
! 11. DB Object Synonym(s) optional
! 12. DB Object Type
! 13. Taxon taxon:10090
! 14. Date YYYYMMDD
! 15. Assigned By
! 16. Annotation Extension same as GPAD/col 11
! 17. Gene Product Form ID Isorform
!

Contents

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gorule-0000027

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gorule-0000029

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gorule-0000042

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other

MESSAGES

gorule-0000001

GAF lines are parsed according to GAF 2.1 specifications

Messages

gorule-0000002

No 'NOT' annotations to 'protein binding ; GO:0005515'

gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology

Messages

gorule-0000007

IPI should not be used with GO:0003824 catalytic activity or descendents

gorule-0000008

No annotations should be made to uninformative high level terms

Messages

gorule-0000011

ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

gorule-0000013

Taxon-appropriate annotation check

Messages

gorule-0000015

Dual species taxon check

gorule-0000016

With/From: IC annotations require a With/From GO ID

gorule-0000017

IDA annotations must not have a With/From entry

Messages

gorule-0000018

IPI annotations require a With/From entry

Messages

gorule-0000027

Each identifier in GAF is valid

Messages

gorule-0000028

Aspect can only be one of C, P, F and should be repaired using the GO term

gorule-0000029

All IEAs over a year old are removed

gorule-0000030

Deprecated GO_REFs are not allowed

gorule-0000037

IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference

gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

gorule-0000042

Qualifier: IKR evidence code requires a NOT qualifier

gorule-0000043

Check for valid combination of evidence code and GO_REF

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.

Messages

gorule-0000050

Annotations to ISS, ISA and ISO should not be self-referential

gorule-0000057

Group specific filter rules should be applied to annotations

gorule-0000058

Object extensions should conform to the extensions-patterns.yaml file in metadata

other

Predictions

GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0004721 phosphoprotein phosphatase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0017077 oxidative phosphorylation uncoupler activity IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015179 L-amino acid transmembrane transporter activity IBA
GO:0036261 7-methylguanosine cap hypermethylation AnnotationPropagation P GO:0071164 RNA trimethylguanosine synthase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:1901679 nucleotide transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0015867 ATP transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:1902358 sulfate transmembrane transport AnnotationPropagation P GO:0015116 sulfate transmembrane transporter activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0004842 ubiquitin-protein transferase activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0061025 membrane fusion AnnotationPropagation P GO:0005484 SNAP receptor activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004997 thyrotropin-releasing hormone receptor activity IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0008237 metallopeptidase activity IBA
GO:0035335 peptidyl-tyrosine dephosphorylation AnnotationPropagation P GO:0004725 protein tyrosine phosphatase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004601 peroxidase activity IBA
GO:0098869 cellular oxidant detoxification AnnotationPropagation P GO:0004601 peroxidase activity IBA
GO:0090501 RNA phosphodiester bond hydrolysis AnnotationPropagation P GO:0004540 ribonuclease activity IBA
GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0004721 phosphoprotein phosphatase activity IBA
GO:0016310 phosphorylation AnnotationPropagation P GO:0004496 mevalonate kinase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004029 aldehyde dehydrogenase (NAD+) activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity IBA
GO:0038166 angiotensin-activated signaling pathway AnnotationPropagation P GO:0001595 angiotensin receptor activity IBA
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste AnnotationPropagation P GO:0033038 bitter taste receptor activity IBA
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity AnnotationPropagation P GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IDA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0018685 alkane 1-monooxygenase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0097503 sialylation AnnotationPropagation P GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008475 procollagen-lysine 5-dioxygenase activity IBA
GO:0006470 protein dephosphorylation AnnotationPropagation P GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity IBA
GO:0016055 Wnt signaling pathway AnnotationPropagation P GO:0042813 Wnt-activated receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022829 wide pore channel activity IBA
GO:0099173 postsynapse organization AnnotationPropagation P GO:0099186 structural constituent of postsynapse ISO
GO:0050808 synapse organization AnnotationPropagation P GO:0099186 structural constituent of postsynapse ISO
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0005242 inward rectifier potassium channel activity IBA
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity AnnotationPropagation P GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015171 amino acid transmembrane transporter activity IBA
GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity ISO
GO:1902476 chloride transmembrane transport AnnotationPropagation P GO:0015108 chloride transmembrane transporter activity IBA
GO:0030488 tRNA methylation AnnotationPropagation P GO:0016423 tRNA (guanine) methyltransferase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0070553 nicotinic acid receptor activity ISO
GO:0009972 cytidine deamination AnnotationPropagation P GO:0004126 cytidine deaminase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway ISO
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0071897 DNA biosynthetic process AnnotationPropagation P GO:0003887 DNA-directed DNA polymerase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA
GO:0000122 negative regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0071805 potassium ion transmembrane transport AnnotationPropagation P GO:0005249 voltage-gated potassium channel activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:1901679 nucleotide transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0015867 ATP transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste AnnotationPropagation P GO:0033038 bitter taste receptor activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process ISO
GO:0016573 histone acetylation AnnotationPropagation P GO:0004402 histone acetyltransferase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0032147 activation of protein kinase activity AnnotationPropagation P GO:0030295 protein kinase activator activity IBA
GO:0006165 nucleoside diphosphate phosphorylation AnnotationPropagation P GO:0004550 nucleoside diphosphate kinase activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0046961 proton-transporting ATPase activity, rotational mechanism IBA
GO:0007160 cell-matrix adhesion AnnotationPropagation P GO:0098639 collagen binding involved in cell-matrix adhesion ISO
GO:0045202 synapse AnnotationPropagation C GO:0007268 chemical synaptic transmission IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0018108 peptidyl-tyrosine phosphorylation AnnotationPropagation P GO:0004714 transmembrane receptor protein tyrosine kinase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0016361 activin receptor activity, type I IBA
GO:0032924 activin receptor signaling pathway AnnotationPropagation P GO:0016361 activin receptor activity, type I IBA
GO:0016310 phosphorylation AnnotationPropagation P GO:0000828 inositol hexakisphosphate kinase activity IBA
GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0005245 voltage-gated calcium channel activity IBA
GO:0030488 tRNA methylation AnnotationPropagation P GO:0016423 tRNA (guanine) methyltransferase activity IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0045148 tripeptide aminopeptidase activity IDA
GO:0015718 monocarboxylic acid transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA
GO:1905039 carboxylic acid transmembrane transport AnnotationPropagation P GO:0008028 monocarboxylic acid transmembrane transporter activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0015385 sodium:proton antiporter activity IBA
GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0015385 sodium:proton antiporter activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0036139 peptidyl-histidine dioxygenase activity IBA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0016791 phosphatase activity IBA
GO:0016310 phosphorylation AnnotationPropagation P GO:0004594 pantothenate kinase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004028 3-chloroallyl aldehyde dehydrogenase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0046854 phosphatidylinositol phosphorylation AnnotationPropagation P GO:0052742 phosphatidylinositol kinase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0034204 lipid translocation AnnotationPropagation P GO:0090555 phosphatidylethanolamine flippase activity IBA
GO:0015914 phospholipid transport AnnotationPropagation P GO:0090555 phosphatidylethanolamine flippase activity IBA
GO:1901679 nucleotide transmembrane transport AnnotationPropagation P GO:0080122 AMP transmembrane transporter activity ISO
GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0080122 AMP transmembrane transporter activity ISO
GO:0080121 AMP transport AnnotationPropagation P GO:0080122 AMP transmembrane transporter activity ISO
GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0080122 AMP transmembrane transporter activity ISO
GO:0006508 proteolysis AnnotationPropagation P GO:0004222 metalloendopeptidase activity IBA
GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0000122 negative regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0016310 phosphorylation AnnotationPropagation P GO:0016301 kinase activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0022900 electron transport chain AnnotationPropagation P GO:0009055 electron transfer activity IBA
GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0015914 phospholipid transport AnnotationPropagation P GO:1990050 phosphatidic acid transfer activity IBA
GO:0120009 intermembrane lipid transfer AnnotationPropagation P GO:1990050 phosphatidic acid transfer activity IBA
GO:0005783 endoplasmic reticulum AnnotationPropagation C GO:0006621 protein retention in ER lumen IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0004198 calcium-dependent cysteine-type endopeptidase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:1990180 mitochondrial tRNA 3'-end processing ISO
GO:0007256 activation of JNKK activity AnnotationPropagation P GO:0004706 JUN kinase kinase kinase activity IBA
GO:0000165 MAPK cascade AnnotationPropagation P GO:0004706 JUN kinase kinase kinase activity IBA
GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004999 vasoactive intestinal polypeptide receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0005737 cytoplasm AnnotationPropagation C GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport IBA
GO:0015698 inorganic anion transport AnnotationPropagation P GO:0008308 voltage-gated anion channel activity IBA
GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0008308 voltage-gated anion channel activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004683 calmodulin-dependent protein kinase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0035335 peptidyl-tyrosine dephosphorylation AnnotationPropagation P GO:0004725 protein tyrosine phosphatase activity IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0008233 peptidase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0005829 cytosol AnnotationPropagation C GO:0042147 retrograde transport, endosome to Golgi IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004497 monooxygenase activity IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0030488 tRNA methylation AnnotationPropagation P GO:0016300 tRNA (uracil) methyltransferase activity IBA
GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0005261 cation channel activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity IBA
GO:0034220 ion transmembrane transport AnnotationPropagation P GO:0005216 ion channel activity IBA
GO:0006412 translation AnnotationPropagation P GO:0016149 translation release factor activity, codon specific IBA
GO:0006415 translational termination AnnotationPropagation P GO:0016149 translation release factor activity, codon specific IBA
GO:0006417 regulation of translation AnnotationPropagation P GO:0016149 translation release factor activity, codon specific IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0004931 extracellularly ATP-gated cation channel activity IBA
GO:0060079 excitatory postsynaptic potential AnnotationPropagation P GO:0004931 extracellularly ATP-gated cation channel activity IBA
GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0007006 mitochondrial membrane organization IDA
GO:0005634 nucleus AnnotationPropagation C GO:0051457 maintenance of protein location in nucleus ISO
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061631 ubiquitin conjugating enzyme activity IBA
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic AnnotationPropagation P GO:0004521 endoribonuclease activity IBA
GO:0006633 fatty acid biosynthetic process AnnotationPropagation P GO:0000036 acyl carrier activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0016310 phosphorylation AnnotationPropagation P GO:0046316 gluconokinase activity IBA
GO:0035435 phosphate ion transmembrane transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISO
GO:0015712 hexose phosphate transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISO
GO:0015711 organic anion transport AnnotationPropagation P GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity ISO
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0015295 solute:proton symporter activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0043666 regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0019888 protein phosphatase regulator activity IBA
GO:0006657 CDP-choline pathway AnnotationPropagation P GO:0004105 choline-phosphate cytidylyltransferase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0050113 inositol oxygenase activity IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0008239 dipeptidyl-peptidase activity IBA
GO:0007165 signal transduction AnnotationPropagation P GO:0008083 growth factor activity IBA
GO:0050790 regulation of catalytic activity AnnotationPropagation P GO:0030234 enzyme regulator activity IBA
GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0003954 NADH dehydrogenase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0047134 protein-disulfide reductase activity IBA
GO:0000413 protein peptidyl-prolyl isomerization AnnotationPropagation P GO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0000249 C-22 sterol desaturase activity IBA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity IBA
GO:0005829 cytosol AnnotationPropagation C GO:0034498 early endosome to Golgi transport IBA
GO:0046835 carbohydrate phosphorylation AnnotationPropagation P GO:0004335 galactokinase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly ISO
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA
GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004867 serine-type endopeptidase inhibitor activity IBA
GO:0006913 nucleocytoplasmic transport AnnotationPropagation P GO:0017056 structural constituent of nuclear pore IBA
GO:0002430 complement receptor mediated signaling pathway AnnotationPropagation P GO:0004876 complement component C3a receptor activity IBA
GO:0090501 RNA phosphodiester bond hydrolysis AnnotationPropagation P GO:0004540 ribonuclease activity IBA
GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA
GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0030424 axon AnnotationPropagation C GO:0099519 dense core granule cytoskeletal transport ISO
GO:0005829 cytosol AnnotationPropagation C GO:0099519 dense core granule cytoskeletal transport ISO
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004672 protein kinase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic AnnotationPropagation P GO:0004521 endoribonuclease activity IBA
GO:0045202 synapse AnnotationPropagation C GO:0007274 neuromuscular synaptic transmission IBA
GO:0043666 regulation of phosphoprotein phosphatase activity AnnotationPropagation P GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity IBA
GO:0030424 axon AnnotationPropagation C GO:0008089 anterograde axonal transport IBA
GO:1904115 axon cytoplasm AnnotationPropagation C GO:0008089 anterograde axonal transport IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0015293 symporter activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006657 CDP-choline pathway AnnotationPropagation P GO:0004142 diacylglycerol cholinephosphotransferase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004322 ferroxidase activity IBA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0006913 nucleocytoplasmic transport AnnotationPropagation P GO:0017056 structural constituent of nuclear pore IBA
GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004869 cysteine-type endopeptidase inhibitor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016491 oxidoreductase activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0046961 proton-transporting ATPase activity, rotational mechanism IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0035335 peptidyl-tyrosine dephosphorylation AnnotationPropagation P GO:0004725 protein tyrosine phosphatase activity IBA
GO:0016020 membrane AnnotationPropagation C GO:0090110 COPII-coated vesicle cargo loading ISO
GO:0000122 negative regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
GO:0007256 activation of JNKK activity AnnotationPropagation P GO:0004706 JUN kinase kinase kinase activity IBA
GO:0000165 MAPK cascade AnnotationPropagation P GO:0004706 JUN kinase kinase kinase activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA
GO:0032508 DNA duplex unwinding AnnotationPropagation P GO:0017116 single-stranded DNA helicase activity IBA
GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0015651 quaternary ammonium group transmembrane transporter activity IBA
GO:0015697 quaternary ammonium group transport AnnotationPropagation P GO:0015651 quaternary ammonium group transmembrane transporter activity IBA
GO:0000122 negative regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
GO:1901679 nucleotide transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0015867 ATP transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004735 pyrroline-5-carboxylate reductase activity IBA
GO:0006355 regulation of transcription, DNA-templated AnnotationPropagation P GO:0003700 DNA-binding transcription factor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0000165 MAPK cascade AnnotationPropagation P GO:0004707 MAP kinase activity IBA
GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0005262 calcium channel activity IBA
GO:1902559 3'-phospho-5'-adenylyl sulfate transmembrane transport AnnotationPropagation P GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0004222 metalloendopeptidase activity IBA
GO:0015701 bicarbonate transport AnnotationPropagation P GO:0015106 bicarbonate transmembrane transporter activity IBA
GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0015106 bicarbonate transmembrane transporter activity IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0004197 cysteine-type endopeptidase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004459 L-lactate dehydrogenase activity IBA
GO:0006259 DNA metabolic process AnnotationPropagation P GO:0004531 deoxyribonuclease II activity IBA
GO:0090305 nucleic acid phosphodiester bond hydrolysis AnnotationPropagation P GO:0004531 deoxyribonuclease II activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016155 formyltetrahydrofolate dehydrogenase activity IBA
GO:0015804 neutral amino acid transport AnnotationPropagation P GO:0015175 neutral amino acid transmembrane transporter activity IBA
GO:0003333 amino acid transmembrane transport AnnotationPropagation P GO:0015175 neutral amino acid transmembrane transporter activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004733 pyridoxamine-phosphate oxidase activity IBA
GO:0042823 pyridoxal phosphate biosynthetic process AnnotationPropagation P GO:0004733 pyridoxamine-phosphate oxidase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0010452 histone H3-K36 methylation AnnotationPropagation P GO:0046975 histone methyltransferase activity (H3-K36 specific) IBA
GO:0035725 sodium ion transmembrane transport AnnotationPropagation P GO:0005248 voltage-gated sodium channel activity IBA
GO:0071108 protein K48-linked deubiquitination AnnotationPropagation P GO:1990380 Lys48-specific deubiquitinase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
GO:0046835 carbohydrate phosphorylation AnnotationPropagation P GO:0004856 xylulokinase activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity IBA
GO:0006508 proteolysis AnnotationPropagation P GO:0042500 aspartic endopeptidase activity, intramembrane cleaving IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death ISO
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004032 alditol:NADP+ 1-oxidoreductase activity IDA
GO:0007165 signal transduction AnnotationPropagation P GO:0008083 growth factor activity IBA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0004674 protein serine/threonine kinase activity IBA
GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0015220 choline transmembrane transporter activity IBA
GO:0015871 choline transport AnnotationPropagation P GO:0015220 choline transmembrane transporter activity IBA
GO:0050790 regulation of catalytic activity AnnotationPropagation P GO:0048270 methionine adenosyltransferase regulator activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity TAS
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste AnnotationPropagation P GO:0033038 bitter taste receptor activity IBA
GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic AnnotationPropagation P GO:0042781 3'-tRNA processing endoribonuclease activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0005315 inorganic phosphate transmembrane transporter activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0008940 nitrate reductase activity IBA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0003993 acid phosphatase activity IDA
GO:0006657 CDP-choline pathway AnnotationPropagation P GO:0004105 choline-phosphate cytidylyltransferase activity IBA
GO:0043547 positive regulation of GTPase activity AnnotationPropagation P GO:0005096 GTPase activator activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0007268 chemical synaptic transmission AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IBA
GO:0034220 ion transmembrane transport AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IBA
GO:0060078 regulation of postsynaptic membrane potential AnnotationPropagation P GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential IBA
GO:0007165 signal transduction AnnotationPropagation P GO:0005125 cytokine activity IBA
GO:1903508 positive regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003713 transcription coactivator activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0001758 retinal dehydrogenase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:1903508 positive regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0030374 nuclear receptor transcription coactivator activity IBA
GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS
GO:0055085 transmembrane transport AnnotationPropagation P GO:0042626 ATPase-coupled transmembrane transporter activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0047057 vitamin-K-epoxide reductase (warfarin-sensitive) activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0055085 transmembrane transport AnnotationPropagation P GO:0022857 transmembrane transporter activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IBA
GO:0007165 signal transduction AnnotationPropagation P GO:0008083 growth factor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0016567 protein ubiquitination AnnotationPropagation P GO:0061630 ubiquitin protein ligase activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0010951 negative regulation of endopeptidase activity AnnotationPropagation P GO:0004869 cysteine-type endopeptidase inhibitor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004497 monooxygenase activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0047837 D-xylose 1-dehydrogenase (NADP+) activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism IBA
GO:0045944 positive regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:1901679 nucleotide transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0015867 ATP transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0098656 anion transmembrane transport AnnotationPropagation P GO:0005347 ATP transmembrane transporter activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004499 N,N-dimethylaniline monooxygenase activity IBA
GO:1903506 regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003712 transcription coregulator activity IBA
GO:0045202 synapse AnnotationPropagation C GO:0007268 chemical synaptic transmission IBA
GO:0006357 regulation of transcription by RNA polymerase II AnnotationPropagation P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004833 tryptophan 2,3-dioxygenase activity IBA
GO:0090501 RNA phosphodiester bond hydrolysis AnnotationPropagation P GO:0004540 ribonuclease activity IBA
GO:1902600 proton transmembrane transport AnnotationPropagation P GO:0015333 peptide:proton symporter activity IBA
GO:0042886 amide transport AnnotationPropagation P GO:0015333 peptide:proton symporter activity IBA
GO:0006412 translation AnnotationPropagation P GO:0030533 triplet codon-amino acid adaptor activity ISS
GO:0070588 calcium ion transmembrane transport AnnotationPropagation P GO:0005262 calcium channel activity IBA
GO:0098609 cell-cell adhesion AnnotationPropagation P GO:0098632 cell-cell adhesion mediator activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0016791 phosphatase activity ISO
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0055114 oxidation-reduction process AnnotationPropagation P GO:0004029 aldehyde dehydrogenase (NAD+) activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0032979 protein insertion into mitochondrial inner membrane from matrix IBA
GO:0098655 cation transmembrane transport AnnotationPropagation P GO:0004931 extracellularly ATP-gated cation channel activity IBA
GO:0060079 excitatory postsynaptic potential AnnotationPropagation P GO:0004931 extracellularly ATP-gated cation channel activity IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0004930 G protein-coupled receptor activity IBA
GO:0050911 detection of chemical stimulus involved in sensory perception of smell AnnotationPropagation P GO:0004984 olfactory receptor activity IBA
GO:1902475 L-alpha-amino acid transmembrane transport AnnotationPropagation P GO:0015179 L-amino acid transmembrane transporter activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0034551 mitochondrial respiratory chain complex III assembly IBA
GO:0046834 lipid phosphorylation AnnotationPropagation P GO:0001729 ceramide kinase activity IBA
GO:0005739 mitochondrion AnnotationPropagation C GO:0033617 mitochondrial cytochrome c oxidase assembly IBA
GO:1903507 negative regulation of nucleic acid-templated transcription AnnotationPropagation P GO:0003714 transcription corepressor activity IBA
GO:0060078 regulation of postsynaptic membrane potential AnnotationPropagation P GO:0099530 G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential IBA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0099530 G protein-coupled receptor activity involved in regulation of pos