Table of contents

Summary

GAF summary

Found 102942 annotations in 102961 lines.

GAF Validation Summary Errors are reported first.

For rule GO_AR:0000011 (http://www.geneontology.org/GO.annotation_qc.shtml#GO_AR:0000011) ND annotations to root nodes only, there is one violation with type Warning.

GAF Prediction Summary

Found 15 predictions, see prediction file for details.

Used Ontology Summary

go/extensions/go-gaf

Report

Group: goa - Dataset: goa_human_isoform

SUMMARY

This report generated on 2019-04-22

Header From Original Association File

!gaf-version: 2.1
!
!The set of protein accessions included in this file is based on UniProt complete proteomes, which may provide more than one protein per gene.
!They include all Swiss-Prot entries for the species plus any TrEMBL entries that have an Ensembl DR line. The TrEMBL entries are likely to overlap with the Swiss-Prot entries or their isoforms.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!Generated: 2019-04-08 12:05
!GO-version: http://purl.obolibrary.org/obo/go/releases/2019-03-29/extensions/go-plus.owl
!

Contents

gorule-0000008

gorule-0000020

gorule-0000027

other

MESSAGES

gorule-0000008

No annotations should be made to uninformative high level terms

Messages

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

Messages

gorule-0000027

Each identifier in GAF is valid

Messages

other

OWLTools check

#Line number RuleID ViolationType Message Line
#------------
#------------
# Validation for #102942 annotations in 102961 lines
#------------
#Line number RuleID ViolationType Message Line
#------------
# GO_AR:0000011 ND annotations to root nodes only Warning count: 1
101502 GO_AR:0000011 Warning ND annotations to root require reference ID UniProtKB Q9Y4H4 GPSM3 GO:0003674 PMID:2259622 ND F G-protein-signaling modulator 3 GPSM3|G18.1a protein taxon:9606 20061026 UniProt UniProtKB:Q9Y4H5
#------------

Predictions

GO:0005623 cell AnnotationPropagation C GO:0051481 negative regulation of cytosolic calcium ion concentration IDA
GO:0016925 protein sumoylation AnnotationPropagation P GO:0061665 SUMO ligase activity IDA
GO:0005739 mitochondrion AnnotationPropagation C GO:0042407 cristae formation IMP
GO:0006508 proteolysis AnnotationPropagation P GO:0008236 serine-type peptidase activity IDA
GO:0120012 intermembrane sphingolipid transfer AnnotationPropagation P GO:0120017 intermembrane ceramide transfer activity IDA
GO:0035627 ceramide transport AnnotationPropagation P GO:0120017 intermembrane ceramide transfer activity IDA
GO:0007186 G protein-coupled receptor signaling pathway AnnotationPropagation P GO:0016520 growth hormone-releasing hormone receptor activity NAS
GO:0005623 cell AnnotationPropagation C GO:0006611 protein export from nucleus IDA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity IDA
GO:0005623 cell AnnotationPropagation C GO:0016558 protein import into peroxisome matrix IMP
GO:0005634 nucleus FoldBasedPredictor GO:2000377 regulation of reactive oxygen species metabolic process occurs_in GO:0005634 nucleus IMP
GO:0008142 oxysterol binding FoldBasedPredictor GO:0015485 cholesterol binding has_input CHEBI:42977 25-hydroxycholesterol IDA
GO:0043433 negative regulation of DNA-binding transcription factor activity FoldBasedPredictor GO:0061665 SUMO ligase activity has_direct_input UniProtKB:P17861-2 part_of GO:0043433 negative regulation of DNA-binding transcription factor activity IDA
GO:0031644 regulation of neurological system process FoldBasedPredictor GO:0051260 protein homooligomerization happens_during GO:0018105 peptidyl-serine phosphorylation happens_during UBERON:0018241 occurs_in UBERON:0002421 hippocampal formation regulates GO:0007611 learning or memory IMP
GO:0050795 regulation of behavior FoldBasedPredictor GO:0051260 protein homooligomerization happens_during GO:0018105 peptidyl-serine phosphorylation happens_during UBERON:0018241 occurs_in UBERON:0002421 hippocampal formation regulates GO:0007611 learning or memory IMP

Predictions (experimental)