Table of contents

Report

Group: goa - Dataset: goa_human_isoform

SUMMARY

This report generated on 2021-09-22

Header From Original Association File

!gaf-version: 2.2
!
!The set of protein accessions included in this file is based on UniProt complete proteomes, which may provide more than one protein per gene.
!They include all Swiss-Prot entries for the species plus any TrEMBL entries that have an Ensembl DR line. The TrEMBL entries are likely to overlap with the Swiss-Prot entries or their isoforms.
!If a particular protein accession is not annotated with GO, then it will not appear in this file.
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!date-generated: 2021-06-16 11:37
!generated-by: UniProt
!go-version: http://purl.obolibrary.org/obo/go/releases/2021-06-06/extensions/go-plus.owl
!

Contents

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other

MESSAGES

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No 'NOT' annotations to 'protein binding ; GO:0005515'

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IEP and HEP usage is restricted to terms from the Biological Process ontology

Messages

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IPI should not be used with GO:0003824 catalytic activity or descendents

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No annotations should be made to uninformative high level terms

Messages

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ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND

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Taxon-appropriate annotation check

Messages

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Dual species taxon check

Messages

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With/From: IC annotations require a With/From GO ID

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IDA annotations must not have a With/From entry

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IPI annotations require a With/From entry

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Automatic repair of annotations to merged or obsoleted terms

Messages

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Each identifier in GAF is valid

Messages

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Aspect can only be one of C, P, F and should be repaired using the GO term

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IEAs should be less than one year old.

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Deprecated GO_REFs are not allowed

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IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference

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Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

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Qualifier: IKR evidence code requires a NOT qualifier

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Check for valid combination of evidence code and GO_REF

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The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.

Messages

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Annotations to ISS, ISA and ISO should not be self-referential

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References should have only one ID per ID space

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Group specific filter rules should be applied to annotations

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Object extensions should conform to the extensions-patterns.yaml file in metadata

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Allowed gene product to term relations (gp2term)

Messages

other

Predictions

GO:0005813 centrosome FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005813 centrosome IPI
GO:0005829 cytosol FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005829 cytosol IPI
GO:0048471 perinuclear region of cytoplasm FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0048471 perinuclear region of cytoplasm IPI
GO:0036126 sperm flagellum FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0036126 sperm flagellum IPI
GO:0031965 nuclear membrane FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0031965 nuclear membrane IPI
GO:0001726 ruffle FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0001726 ruffle IPI
GO:0043679 axon terminus FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0043679 axon terminus IPI
GO:0043005 neuron projection FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0043005 neuron projection IPI
GO:0005874 microtubule FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005874 microtubule IPI
GO:0005886 plasma membrane FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005886 plasma membrane IPI
GO:0016234 inclusion body FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0016234 inclusion body IPI
GO:0044295 axonal growth cone FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0044295 axonal growth cone IPI
GO:0005737 cytoplasm FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005737 cytoplasm IPI
GO:0005622 intracellular anatomical structure FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005622 intracellular anatomical structure IPI
GO:0048471 perinuclear region of cytoplasm FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0048471 perinuclear region of cytoplasm IPI
GO:0038061 NIK/NF-kappaB signaling FoldBasedPredictor GO:0045944 positive regulation of transcription by RNA polymerase II has_input UniProtKB:P29475 part_of GO:0038061 NIK/NF-kappaB signaling IDA
GO:0005886 plasma membrane FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005886 plasma membrane IPI
GO:0005886 plasma membrane FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005886 plasma membrane IPI
GO:0005737 cytoplasm FoldBasedPredictor GO:0005515 protein binding occurs_in GO:0005737 cytoplasm IPI
GO:0051668 localization within membrane FoldBasedPredictor GO:1902475 L-alpha-amino acid transmembrane transport has_input CHEBI:17929 N(omega),N(omega)-dimethyl-L-arginine has_target_start_location GO:0009897 external side of plasma membrane has_target_end_location GO:0009898 cytoplasmic side of plasma membrane IDA
GO:0008142 oxysterol binding FoldBasedPredictor GO:0015485 cholesterol binding has_input CHEBI:42977 25-hydroxycholesterol IDA

Predictions (experimental)