Table of contents

Summary

GAF summary

Found 1362 annotations in 1377 lines.

GAF Validation Summary

No errors, warnings, or recommendations to report.

Used Ontology Summary

go/extensions/go-gaf

GAF Prediction Summary

Found 31 predictions, see prediction file for details.

Used Ontology Summary

go/extensions/go-gaf

Report

Group: goa - Dataset: goa_human_complex

SUMMARY

This report generated on 2018-12-11

Contents

gorule-0000008

gorule-0000018

other

MESSAGES

gorule-0000008

No annotations should be made to uninformative high level terms

Messages

gorule-0000018

IPI annotations require a With/From entry

Messages

other

OWLTools check

#Line number RuleID ViolationType Message Line
#------------
#------------
# Validation for #1362 annotations in 1377 lines
#------------
# No errors, warnings, or recommendations to report.

Predictions

GO:0051170 import into nucleus AnnotationPropagation P GO:0061608 nuclear import signal receptor activity IDA
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0006479 protein methylation AnnotationPropagation P GO:0008276 protein methyltransferase activity IDA
GO:0005739 mitochondrion AnnotationPropagation C GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IDA
GO:0016311 dephosphorylation AnnotationPropagation P GO:0016791 phosphatase activity IDA
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0043984 histone H4-K16 acetylation AnnotationPropagation P GO:0046972 histone acetyltransferase activity (H4-K16 specific) IDA
GO:0010466 negative regulation of peptidase activity AnnotationPropagation P GO:0030414 peptidase inhibitor activity IDA
GO:0006508 proteolysis AnnotationPropagation P GO:0008233 peptidase activity IDA
GO:0005623 cell AnnotationPropagation C GO:1905665 positive regulation of calcium ion import across plasma membrane IGI
GO:0006259 DNA metabolic process AnnotationPropagation P GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity IMP
GO:0090305 nucleic acid phosphodiester bond hydrolysis AnnotationPropagation P GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity IMP
GO:0005623 cell AnnotationPropagation C GO:0051209 release of sequestered calcium ion into cytosol IDA
GO:0006508 proteolysis AnnotationPropagation P GO:0008233 peptidase activity IDA
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0051726 regulation of cell cycle AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0006468 protein phosphorylation AnnotationPropagation P GO:0097472 cyclin-dependent protein kinase activity IDA
GO:0051170 import into nucleus AnnotationPropagation P GO:0061608 nuclear import signal receptor activity IDA
GO:0006303 double-strand break repair via nonhomologous end joining FoldBasedPredictor GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity occurs_at GO:0000784 nuclear chromosome, telomeric region part_of GO:0006303 double-strand break repair via nonhomologous end joining IMP
GO:1905581 positive regulation of low-density lipoprotein particle clearance FoldBasedPredictor GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport has_direct_input GO:0034362 low-density lipoprotein particle part_of GO:0001921 positive regulation of receptor recycling part_of GO:0032385 positive regulation of intracellular cholesterol transport part_of GO:1905581 positive regulation of low-density lipoprotein particle clearance part_of GO:1905597 positive regulation of low-density lipoprotein particle receptor binding part_of GO:1905599 positive regulation of low-density lipoprotein receptor activity part_of GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport IDA
GO:1905599 positive regulation of low-density lipoprotein receptor activity FoldBasedPredictor GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport has_direct_input GO:0034362 low-density lipoprotein particle part_of GO:0001921 positive regulation of receptor recycling part_of GO:0032385 positive regulation of intracellular cholesterol transport part_of GO:1905581 positive regulation of low-density lipoprotein particle clearance part_of GO:1905597 positive regulation of low-density lipoprotein particle receptor binding part_of GO:1905599 positive regulation of low-density lipoprotein receptor activity part_of GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport IDA
GO:1905597 positive regulation of low-density lipoprotein particle receptor binding FoldBasedPredictor GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport has_direct_input GO:0034362 low-density lipoprotein particle part_of GO:0001921 positive regulation of receptor recycling part_of GO:0032385 positive regulation of intracellular cholesterol transport part_of GO:1905581 positive regulation of low-density lipoprotein particle clearance part_of GO:1905597 positive regulation of low-density lipoprotein particle receptor binding part_of GO:1905599 positive regulation of low-density lipoprotein receptor activity part_of GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport IDA
GO:0001921 positive regulation of receptor recycling FoldBasedPredictor GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport has_direct_input GO:0034362 low-density lipoprotein particle part_of GO:0001921 positive regulation of receptor recycling part_of GO:0032385 positive regulation of intracellular cholesterol transport part_of GO:1905581 positive regulation of low-density lipoprotein particle clearance part_of GO:1905597 positive regulation of low-density lipoprotein particle receptor binding part_of GO:1905599 positive regulation of low-density lipoprotein receptor activity part_of GO:1905602 positive regulation of receptor-mediated endocytosis involved in cholesterol transport IDA
GO:0033554 cellular response to stress FoldBasedPredictor GO:2000363 positive regulation of prostaglandin-E synthase activity has_output CHEBI:15551 prostaglandin E2 occurs_in CL:0000243 glial cell (sensu Vertebrata) occurs_in UBERON:0001891 midbrain part_of GO:0033554 cellular response to stress regulates_o_occurs_in CL:0000243 glial cell (sensu Vertebrata) ISS
GO:0007596 blood coagulation FoldBasedPredictor GO:0016485 protein processing has_direct_input UniProtKB:P00742 occurs_in CL:0002618 endothelial cell of umbilical vein part_of GO:0007596 blood coagulation IDA
GO:0097458 neuron part FoldBasedPredictor GO:0098978 glutamatergic synapse part_of CL:0002608 hippocampal neuron IDA
GO:1904356 regulation of telomere maintenance via telomere lengthening FoldBasedPredictor GO:0098505 G-rich strand telomeric DNA binding part_of GO:0051974 negative regulation of telomerase activity part_of GO:1904356 regulation of telomere maintenance via telomere lengthening IDA
GO:0051974 negative regulation of telomerase activity FoldBasedPredictor GO:0098505 G-rich strand telomeric DNA binding part_of GO:0051974 negative regulation of telomerase activity part_of GO:1904356 regulation of telomere maintenance via telomere lengthening IDA

Predictions (experimental)