#Line number RuleID ViolationType Message Line #------------ #------------ # Validation for #140668 annotations in 140687 lines #------------ #Line number RuleID ViolationType Message Line #------------ # GO_AR:0000005 No ISS or ISS-related annotations to 'protein binding ; GO:0005515' Error count: 7 29424 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB A2VDW9 IKZF3 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9UKT9 F Zinc finger protein Aiolos IKZF3|ZNFN1A3 protein taxon:9913 20191111 UniProt 53102 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt 98608 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt 100208 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase 106257 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt 126226 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt 126677 GO_AR:0000005 Error No ISS or ISS-related annotations to 'protein binding ; GO:0005515' UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt #------------ # GO_AR:0000014 Valid GO term ID Error count: 12 97035 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 97035 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0010867 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 97045 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 97045 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045542 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 97047 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 97047 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 97048 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 97048 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0045723 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 97053 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 97053 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:0071073 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001911),has_agent(UBERON:0002107),occurs_in(UBERON:0001013) 97054 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) 97054 GO_AR:0000014 Error The relation 'has_agent' in the c16 annotation extension is an obsolete relation UniProtKB P01246 GH1 GO:1900482 PMID:2731415 IDA P Somatotropin GH1|GH protein taxon:9913 20150522 AgBase happens_during(GO:0007595),has_agent(UBERON:0001013),has_agent(UBERON:0002107),occurs_in(UBERON:0001911) #------------ # GO_AR:0000003 Annotations to 'binding ; GO:0005488' and 'protein binding ; GO:0005515' should be made with IPI and an interactor in the 'with' field Warning count: 8 29424 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB A2VDW9 IKZF3 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9UKT9 F Zinc finger protein Aiolos IKZF3|ZNFN1A3 protein taxon:9913 20191111 UniProt 53102 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB E1BJ75 CRTAP GO:0005515 GO_REF:0000024 ISS UniProtKB:Q90830 F Cartilage associated protein CRTAP protein taxon:9913 20180925 UniProt 97817 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P04272 ANXA2 GO:0005515 PMID:18597635 TAS F Annexin A2 ANXA2|ANX2 protein taxon:9913 20140514 AgBase 98608 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P08169 IGF2R GO:0005515 GO_REF:0000024 ISS UniProtKB:P11717 F Cation-independent mannose-6-phosphate receptor IGF2R|M6P protein taxon:9913 20091210 UniProt 100208 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P18341 TGFB1 GO:0005515 GO_REF:0000024 ISS UniProtKB:P01137 F Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20141202 AgBase 106257 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB P80311 PPIB GO:0005515 GO_REF:0000024 ISS UniProtKB:P24367 F Peptidyl-prolyl cis-trans isomerase B PPIB protein taxon:9913 20180925 UniProt 126226 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3MHX6 OS9 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q13438 F Protein OS-9 OS9 protein taxon:9913 20090907 UniProt 126677 GO_AR:0000003 Warning Annotations to 'binding' (GO:0005488) and 'protein binding' (GO:0005515) should be made with an IPI evidence code and the interactor in the 'with' field UniProtKB Q3SX24 FBXO6 GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9QZN4 F F-box only protein 6 FBXO6|FBS2|FBX6 protein taxon:9913 20090903 UniProt #------------ # GO_AR:0000008 No annotations should be made to uninformative high level terms Warning count: 17 1208 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A0A3Q1LH95 MAP3K20 GO:0007093 GO_REF:0000107 IEA UniProtKB:Q9NYL2|ensembl:ENSP00000364361 P Uncharacterized protein MAP3K20 protein taxon:9913 20200714 Ensembl 2019 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A0A3Q1LKB7 HRAS GO:0007093 GO_REF:0000107 IEA UniProtKB:P01112|ensembl:ENSP00000407586 P HRas proto-oncogene, GTPase HRAS protein taxon:9913 20200714 Ensembl 3001 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A0A3Q1LMY8 A0A3Q1LMY8 GO:0007093 GO_REF:0000002 IEA InterPro:IPR018630 P Protein zwilch homolog protein taxon:9913 20200808 InterPro 18872 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A0A3Q1MPF5 WNT9A GO:0007093 GO_REF:0000107 IEA UniProtKB:O14904|ensembl:ENSP00000272164 P Protein Wnt WNT9A protein taxon:9913 20200714 Ensembl 25648 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A0A3S5ZPT8 MAD2L1BP GO:0007093 GO_REF:0000107 IEA UniProtKB:Q15013|ensembl:ENSP00000410818 P MAD2L1 binding protein MAD2L1BP protein taxon:9913 20200714 Ensembl 35574 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A6QLK2 NABP2 GO:0007093 GO_REF:0000024 ISS UniProtKB:Q9BQ15 P SOSS complex subunit B1 NABP2|OBFC2B|SSB1 protein taxon:9913 20130918 UniProt 36192 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB A6QM04 ZWILCH GO:0007093 GO_REF:0000024 ISS UniProtKB:Q9H900 P Protein zwilch homolog ZWILCH protein taxon:9913 20080201 UniProt 45342 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB E1BBQ0 KNTC1 GO:0007093 GO_REF:0000107 IEA UniProtKB:P50748|ensembl:ENSP00000328236 P Rod_C domain-containing protein KNTC1 protein taxon:9913 20200714 Ensembl 49399 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB E1BFI5 DCLRE1B GO:0007093 GO_REF:0000107 IEA UniProtKB:Q9H816|ensembl:ENSP00000498042 P Lactamase_B domain-containing protein DCLRE1B protein taxon:9913 20200714 Ensembl 57393 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB E1BN70 INTS3 GO:0007093 GO_REF:0000107 IEA UniProtKB:Q68E01|ensembl:ENSP00000318641 P Integrator complex subunit 3 INTS3 protein taxon:9913 20200714 Ensembl 86313 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB F6Q6K1 CHEK1 GO:0007093 GO_REF:0000107 IEA UniProtKB:O35280|ensembl:ENSMUSP00000134388 P CHK1 checkpoint homolog CHEK1 protein taxon:9913 20200714 Ensembl 100220 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB P18341 TGFB1 GO:0007093 GO_REF:0000024 ISS UniProtKB:P01137 P Transforming growth factor beta-1 proprotein TGFB1 protein taxon:9913 20110812 UniProt 106402 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular anatomical structure' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB P81287 ANXA5 GO:0005622 GO_REF:0000024 ISS UniProtKB:P08758 C Annexin A5 ANXA5|ANX5 protein taxon:9913 20061003 AgBase 118847 GO_AR:0000008 Warning Do not annotate to: GO:0005622 'intracellular anatomical structure' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q2HJ92 PRKRA GO:0005622 GO_REF:0000024 ISS UniProtKB:Q9WTX2 C Interferon-inducible double-stranded RNA-dependent protein kinase activator A PRKRA protein taxon:9913 20070616 AgBase 121373 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q2KJD8 CDKN2B GO:0007093 GO_REF:0000024 ISS UniProtKB:P42772 P Cyclin-dependent kinase 4 inhibitor B CDKN2B protein taxon:9913 20100203 UniProt 122944 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q2TBH8 ZWINT GO:0007093 GO_REF:0000002 IEA InterPro:IPR029092 P ZW10 interactor ZWINT protein taxon:9913 20200808 InterPro 137554 GO_AR:0000008 Warning Do not annotate to: GO:0007093 'mitotic cell cycle checkpoint' The term is considered to high level, as marked via the subset tag: gocheck_do_not_annotate UniProtKB Q862I1 RPL24 GO:0007093 GO_REF:0000107 IEA UniProtKB:Q8BP67|ensembl:ENSMUSP00000023269 P 60S ribosomal protein L24 RPL24 protein taxon:9913 20200714 Ensembl #------------