This report generated on 2024-05-05
!gaf-version: 2.2
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!date-generated: 2024-04-16 15:19
!generated-by: UniProt
!go-version: http://purl.obolibrary.org/obo/go/releases/2024-04-13/extensions/go-plus.owl
!
No 'NOT' annotations to binding ; GO:0005488 or 'protein binding ; GO:0005515'
IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''
IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC
IPI should not be used with GO:0003824 catalytic activity or descendents
No annotations should be made to uninformative high level terms
ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND
Taxon-appropriate annotation check
Dual species taxon check
With/From: IC annotations require a With/From GO ID
IDA annotations must not have a With/From entry
IPI annotations require a With/From entry
GO aspect should match the term's namespace; otherwise it is repaired to the appropriate aspect
IEAs should be less than one year old.
Obsolete GO_REFs are not allowed
IBA annotations should ONLY be assigned_by GO_Central and have GO_REF:0000033 as a reference
Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants
Qualifier: IKR evidence code requires a NOT qualifier
Check for valid combination of evidence code and GO_REF
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.
Annotations to ISS, ISA and ISO should not be self-referential
References should have only one ID per ID space
Object extensions should conform to the extensions-patterns.yaml file in metadata
Allowed gene product to term relations (gp2term)
Only certain gene product to term relations are allowed for a given GO term but was repaired: BFO:0000050 should be one of RO:0001025, RO:0002325, RO:0002432. Repaired to RO:0001025 -- ComplexPortal CPX-7404 tenascin-c_chick part_of GO:0005604 GO_REF:0000114 ISO ComplexPortal:CPX-471 C Tenascin-C complex TNC hexamer|Cytotactin complex|Hexabrachion complex protein_complex taxon:9031 20220715 ComplexPortalOnly certain gene product to term relations are allowed for a given GO term but was repaired: BFO:0000050 should be one of RO:0001025, RO:0002325, RO:0002432. Repaired to RO:0001025 -- ComplexPortal CPX-7404 tenascin-c_chick part_of GO:0062023 GO_REF:0000114 ISO ComplexPortal:CPX-466 C Tenascin-C complex TNC hexamer|Cytotactin complex|Hexabrachion complex protein_complex taxon:9031 20220715 ComplexPortalOnly certain gene product to term relations are allowed for a given GO term but was repaired: BFO:0000050 should be one of RO:0001025, RO:0002325, RO:0002432. Repaired to RO:0001025 -- ComplexPortal CPX-960 collagen_ii_chick part_of GO:0031012 PMID:26059120 EXP C Collagen type II trimer Type II collagen|COL1A2 trimer protein_complex taxon:9031 20170526 ComplexPortalAnnotations using ISS/ISA/ISO evidence should refer to a gene product (in the 'with' column)
TreeGrafter IEAs should be filtered for GO reference species