This report generated on 2022-05-24
!gaf-version: 2.2
!
!Note that the annotation set in this file is filtered in order to reduce redundancy; the full, unfiltered set can be found in
!ftp://ftp.ebi.ac.uk/pub/databases/GO/goa/UNIPROT/goa_uniprot_all.gaf.gz
!
!date-generated: 2022-05-03 12:03
!generated-by: UniProt
!go-version: http://purl.obolibrary.org/obo/go/releases/2022-04-28/extensions/go-plus.owl
!
No 'NOT' annotations to 'protein binding ; GO:0005515'
IEP and HEP usage is restricted to terms from the Biological Process ontology
IPI should not be used with GO:0003824 catalytic activity or descendents
No annotations should be made to uninformative high level terms
ND evidence code should be to root nodes only, and no terms other than root nodes can have the evidence code ND
Taxon-appropriate annotation check
Dual species taxon check
With/From: IC annotations require a With/From GO ID
ComplexPortal CPX-173 2xchrna4-3xchrnb2_chick enables GO:0022848 PMID:10908297 IC F Neuronal nicotinic acetylcholine receptor complex, 2xalpha4-3xbeta2 ionotropic acetylcholine receptor complex|neuronal acetylcholine receptor; alpha4-beta2|2xCHRNA4:3xCHRNB2|neuronal nicotinic acetylcholine-gated ion channel complex|neuronal nicotinic cholinergic receptor complex, alpha4-beta2|neuronal nicotinic acetylcholine-gated receptor-channel complex|neuronal nicotinic acetylcholine-gated cation channel complex|neuronal nicotinic acetylcholine-gated receptor complex protein_complex taxon:9031 20150825 ComplexPortalComplexPortal CPX-201 chrna3-chrna6-chrnb2-chrnb3_chick enables GO:0022848 GO_REF:0000114 IC ComplexPortal:CPX-187 F Neuronal nicotinic acetylcholine receptor complex, alpha3-alpha6-beta2-beta3 neuronal nicotinic acetylcholine-gated receptor-channel complex|ionotropic acetylcholine receptor complex|CHRNA3:CHRNA6:CHRNB2:CHRNB3|neuronal nicotinic acetylcholine-gated ion channel complex|neuronal nicotinic acetylcholine-gated cation channel complex|neuronal nicotinic cholinergic receptor complex|neuronal acetylcholine receptor; alpha3-alpha6-beta2-beta3|neuronal nicotinic acetylcholine-gated receptor complex protein_complex taxon:9031 20180427 ComplexPortalComplexPortal CPX-201 chrna3-chrna6-chrnb2-chrnb3_chick enables GO:0042166 GO_REF:0000114 IC ComplexPortal:CPX-187 F Neuronal nicotinic acetylcholine receptor complex, alpha3-alpha6-beta2-beta3 neuronal nicotinic acetylcholine-gated receptor-channel complex|ionotropic acetylcholine receptor complex|CHRNA3:CHRNA6:CHRNB2:CHRNB3|neuronal nicotinic acetylcholine-gated ion channel complex|neuronal nicotinic acetylcholine-gated cation channel complex|neuronal nicotinic cholinergic receptor complex|neuronal acetylcholine receptor; alpha3-alpha6-beta2-beta3|neuronal nicotinic acetylcholine-gated receptor complex protein_complex taxon:9031 20180427 ComplexPortalComplexPortal CPX-201 chrna3-chrna6-chrnb2-chrnb3_chick involved_in GO:0051899 GO_REF:0000114 IC ComplexPortal:CPX-187 P Neuronal nicotinic acetylcholine receptor complex, alpha3-alpha6-beta2-beta3 neuronal nicotinic acetylcholine-gated receptor-channel complex|ionotropic acetylcholine receptor complex|CHRNA3:CHRNA6:CHRNB2:CHRNB3|neuronal nicotinic acetylcholine-gated ion channel complex|neuronal nicotinic acetylcholine-gated cation channel complex|neuronal nicotinic cholinergic receptor complex|neuronal acetylcholine receptor; alpha3-alpha6-beta2-beta3|neuronal nicotinic acetylcholine-gated receptor complex protein_complex taxon:9031 20180427 ComplexPortalComplexPortal CPX-214 chrna3-chrna6-chrnb4_chick enables GO:0022848 GO_REF:0000114 IC ComplexPortal:CPX-205 F Neuronal nicotinic acetylcholine receptor complex, alpha3-alpha6-beta4 neuronal nicotinic acetylcholine-gated receptor-channel complex|CHRNA3:CHRNA6:CHRNB4|neuronal nicotinic cholinergic receptor complex|neuronal acetylcholine receptor; alpha3-alpha6-beta4|neuronal nicotinic acetylcholine-gated ion channel complex|neuronal nicotinic acetylcholine-gated cation channel complex|neuronal nicotinic acetylcholine-gated receptor complex|ionotropic acetylcholine receptor complex protein_complex taxon:9031 20180427 ComplexPortalComplexPortal CPX-214 chrna3-chrna6-chrnb4_chick enables GO:0042166 GO_REF:0000114 IC ComplexPortal:CPX-205 F Neuronal nicotinic acetylcholine receptor complex, alpha3-alpha6-beta4 neuronal nicotinic acetylcholine-gated receptor-channel complex|CHRNA3:CHRNA6:CHRNB4|neuronal nicotinic cholinergic receptor complex|neuronal acetylcholine receptor; alpha3-alpha6-beta4|neuronal nicotinic acetylcholine-gated ion channel complex|neuronal nicotinic acetylcholine-gated cation channel complex|neuronal nicotinic acetylcholine-gated receptor complex|ionotropic acetylcholine receptor complex protein_complex taxon:9031 20180427 ComplexPortalComplexPortal CPX-214 chrna3-chrna6-chrnb4_chick involved_in GO:0051899 GO_REF:0000114 IC ComplexPortal:CPX-205 P Neuronal nicotinic acetylcholine receptor complex, alpha3-alpha6-beta4 neuronal nicotinic acetylcholine-gated receptor-channel complex|CHRNA3:CHRNA6:CHRNB4|neuronal nicotinic cholinergic receptor complex|neuronal acetylcholine receptor; alpha3-alpha6-beta4|neuronal nicotinic acetylcholine-gated ion channel complex|neuronal nicotinic acetylcholine-gated cation channel complex|neuronal nicotinic acetylcholine-gated receptor complex|ionotropic acetylcholine receptor complex protein_complex taxon:9031 20180427 ComplexPortalComplexPortal CPX-254 chrna1-chrng_chick enables GO:0022848 PMID:21480901 IC F Muscle-type nicotinic acetylcholine receptor complex, alpha1-beta1-delta-gamma muscle-type nicotinic acetylcholine receptor; alpha1-beta1-delta-gamma|muscle-type nicotinic cholinergic receptor complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated receptor complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated receptor-channel complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated cation channel complex (foetal extrajunctional)|ionotropic acetylcholine receptor complex (foetal extrajunctional)|2xCHRNA1:CHRNB1:CHRND:CHRNG|muscle-type nicotinic cholinergic receptor complex, alpha1-beta1-delta-gamma|muscle-type nicotinic acetylcholine-gated ion channel complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine receptor complex (foetal extrajunctional) protein_complex taxon:9031 20151021 ComplexPortalComplexPortal CPX-254 chrna1-chrng_chick enables GO:0042166 PMID:22841691 IC F Muscle-type nicotinic acetylcholine receptor complex, alpha1-beta1-delta-gamma muscle-type nicotinic acetylcholine receptor; alpha1-beta1-delta-gamma|muscle-type nicotinic cholinergic receptor complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated receptor complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated receptor-channel complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated cation channel complex (foetal extrajunctional)|ionotropic acetylcholine receptor complex (foetal extrajunctional)|2xCHRNA1:CHRNB1:CHRND:CHRNG|muscle-type nicotinic cholinergic receptor complex, alpha1-beta1-delta-gamma|muscle-type nicotinic acetylcholine-gated ion channel complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine receptor complex (foetal extrajunctional) protein_complex taxon:9031 20151021 ComplexPortalComplexPortal CPX-254 chrna1-chrng_chick involved_in GO:0095500 PMID:21480901 IC P Muscle-type nicotinic acetylcholine receptor complex, alpha1-beta1-delta-gamma muscle-type nicotinic acetylcholine receptor; alpha1-beta1-delta-gamma|muscle-type nicotinic cholinergic receptor complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated receptor complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated receptor-channel complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine-gated cation channel complex (foetal extrajunctional)|ionotropic acetylcholine receptor complex (foetal extrajunctional)|2xCHRNA1:CHRNB1:CHRND:CHRNG|muscle-type nicotinic cholinergic receptor complex, alpha1-beta1-delta-gamma|muscle-type nicotinic acetylcholine-gated ion channel complex (foetal extrajunctional)|muscle-type nicotinic acetylcholine receptor complex (foetal extrajunctional) protein_complex taxon:9031 20151021 ComplexPortalComplexPortal CPX-704 rxra-thra_chick enables GO:0000981 PMID:1310350 IC F RXRalpha-TRalpha nuclear hormone receptor complex NR2B1-NR1A1 complex|RXRA:THRA|Thyroid hormone receptor complex protein_complex taxon:9031 20190415 ComplexPortalComplexPortal CPX-704 rxra-thra_chick enables GO:0043565 PMID:1310350 IC F RXRalpha-TRalpha nuclear hormone receptor complex NR2B1-NR1A1 complex|RXRA:THRA|Thyroid hormone receptor complex protein_complex taxon:9031 20190415 ComplexPortalComplexPortal CPX-704 rxra-thra_chick enables GO:0044323 PMID:1310350 IC F RXRalpha-TRalpha nuclear hormone receptor complex NR2B1-NR1A1 complex|RXRA:THRA|Thyroid hormone receptor complex protein_complex taxon:9031 20190415 ComplexPortalComplexPortal CPX-704 rxra-thra_chick enables GO:0070324 PMID:22474364 IC F RXRalpha-TRalpha nuclear hormone receptor complex NR2B1-NR1A1 complex|RXRA:THRA|Thyroid hormone receptor complex protein_complex taxon:9031 20190415 ComplexPortalComplexPortal CPX-704 rxra-thra_chick involved_in GO:0002157 PMID:1310350 IC P RXRalpha-TRalpha nuclear hormone receptor complex NR2B1-NR1A1 complex|RXRA:THRA|Thyroid hormone receptor complex protein_complex taxon:9031 20190415 ComplexPortalComplexPortal CPX-704 rxra-thra_chick involved_in GO:0042789 PMID:1310350 IC P RXRalpha-TRalpha nuclear hormone receptor complex NR2B1-NR1A1 complex|RXRA:THRA|Thyroid hormone receptor complex protein_complex taxon:9031 20190415 ComplexPortalComplexPortal CPX-704 rxra-thra_chick involved_in GO:0045944 PMID:1310350 IC P RXRalpha-TRalpha nuclear hormone receptor complex NR2B1-NR1A1 complex|RXRA:THRA|Thyroid hormone receptor complex protein_complex taxon:9031 20190415 ComplexPortalComplexPortal CPX-960 collagen_ii_chick enables GO:0030020 PMID:26059120 IC F Collagen type II trimer Type II collagen|COL1A2 trimer protein_complex taxon:9031 20170526 ComplexPortalIDA annotations must not have a With/From entry
IPI annotations require a With/From entry
Aspect can only be one of C, P, F and should be repaired using the GO term
IEAs should be less than one year old.
Deprecated GO_REFs are not allowed
IBA annotations should ONLY be assigned_by GO_Central and have PMID:21873635 as a reference
Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants
Qualifier: IKR evidence code requires a NOT qualifier
Check for valid combination of evidence code and GO_REF
The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms.
Annotations to ISS, ISA and ISO should not be self-referential
References should have only one ID per ID space
Group specific filter rules should be applied to annotations
Object extensions should conform to the extensions-patterns.yaml file in metadata
Allowed gene product to term relations (gp2term)
Only certain gene product to term relations are allowed for a given GO term but was repaired: BFO:0000050 should be one of RO:0002432, RO:0001025, RO:0002325 -- ComplexPortal CPX-960 collagen_ii_chick part_of GO:0031012 PMID:26059120 EXP C Collagen type II trimer Type II collagen|COL1A2 trimer protein_complex taxon:9031 20170526 ComplexPortal