GORULE violations assigned by ParkinsonsUK-UCL

Contents

gorule-0000008 No annotations should be made to uninformative high level terms

gorule-0000020 Automatic repair of annotations to merged or obsoleted terms

gorule-0000046 The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

gorule-0000061 Allowed gene product to term relations (gp2term)

gorule-0000065 Annotations to term that are candidates for obsoletion should be removed

MESSAGES

gorule-0000008

No annotations should be made to uninformative high level terms

• total: 18

messages

• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1100513 Lmx1b involved_in GO:0032386 PMID:25915474 IMP P LIM homeobox transcription factor 1-beta protein taxon:10090 20160111 ParkinsonsUK-UCL occurs_in(CL:0000540) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:98958 Wnt5a involved_in GO:0032092 PMID:23109420 IDA P Protein Wnt-5a protein taxon:10090 20170410 ParkinsonsUK-UCL has_input(UniProtKB:Q13009),part_of(GO:0016055),occurs_in(CL:0000700)|has_input(UniProtKB:Q92997),part_of(GO:0016055),occurs_in(CL:0000700) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1261768 Stbd1 involved_in GO:0046907 PMID:27358407 IGI UniProtKB:P70699 P Starch-binding domain-containing protein 1 protein taxon:10090 20161108 ParkinsonsUK-UCL has_end_location(GO:0005764),has_input(CHEBI:28087),occurs_in(UBERON:0002107) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1914740 Ufl1 involved_in GO:0032092 PMID:21494687 TAS P E3 UFM1-protein ligase 1 protein taxon:10090 20161103 ParkinsonsUK-UCL has_input(UniProtKB:P61961),has_input(UniProtKB:Q80WW9) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1890467 Vps35 involved_in GO:0033365 PMID:26203154 IMP P Vacuolar protein sorting-associated protein 35 protein taxon:10090 20170207 ParkinsonsUK-UCL has_input(UniProtKB:P17047),has_end_location(GO:0005802) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`MGI MGI:1891731 Stub1 involved_in GO:0032091 PMID:12150907 IDA P E3 ubiquitin-protein ligase CHIP protein taxon:10090 20140813 ParkinsonsUK-UCL part_of(GO:0031398) `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB O95210 STBD1 involved_in GO:0046907 PMID:27358407 IGI UniProtKB:P70699,UniProtKB:Q8C7E7 P Starch-binding domain-containing protein 1 STBD1|GENX-3414 protein taxon:9606 20161108 ParkinsonsUK-UCL has_end_location(GO:0005764),has_input(CHEBI:28087),occurs_in(UBERON:0002107) UniProtKB:O95210 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P23560 BDNF involved_in GO:1900122 PMID:12130635 IDA P Neurotrophic factor BDNF precursor form BDNF protein taxon:9606 20161027 ParkinsonsUK-UCL has_input(UniProtKB:P46459) UniProtKB:P23560 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P49674 CSNK1E involved_in GO:0032091 PMID:23109420 IDA P Casein kinase I isoform epsilon CSNK1E protein taxon:9606 20151208 ParkinsonsUK-UCL has_input(UniProtKB:Q13009),has_input(UniProtKB:Q92997) UniProtKB:P49674 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P51149 RAB7A involved_in GO:0046907 PMID:22042847 IMP P Ras-related protein Rab-7a RAB7A|RAB7 protein taxon:9606 20211118 ParkinsonsUK-UCL UniProtKB:P51149 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P60228 EIF3E involved_in GO:1902416 PMID:24092755 IPI UniProtKB:O15371,UniProtKB:Q04637,UniProtKB:Q99613 P Eukaryotic translation initiation factor 3 subunit E EIF3E|EIF3S6|INT6 protein taxon:9606 20161031 ParkinsonsUK-UCL has_input(UniProtKB:Q04637) UniProtKB:P60228 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P63027 VAMP2 located_in GO:0043231 GO_REF:0000024 ISS UniProtKB:P63045 C Vesicle-associated membrane protein 2 VAMP2|SYB2 protein taxon:9606 20140922 ParkinsonsUK-UCL UniProtKB:P63027 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13009 TIAM1 involved_in GO:0032092 PMID:23109420 IDA P Rho guanine nucleotide exchange factor TIAM1 TIAM1 protein taxon:9606 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63000),has_input(UniProtKB:O14641),part_of(GO:2000050) UniProtKB:Q13009 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13526 PIN1 involved_in GO:0032091 PMID:11533658 IDA P Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 protein taxon:9606 20160114 ParkinsonsUK-UCL has_input(UniProtKB:P25054),has_input(UniProtKB:P35222) UniProtKB:Q13526 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q96D46 NMD3 involved_in GO:0032092 PMID:12724356 IMP P 60S ribosomal export protein NMD3 NMD3|CGI-07 protein taxon:9606 20170626 ParkinsonsUK-UCL has_input(UniProtKB:O14980),has_input(UniProtKB:P62826) UniProtKB:Q96D46 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q99613 EIF3C involved_in GO:1902416 PMID:24092755 IPI UniProtKB:O15371,UniProtKB:P60228,UniProtKB:Q04637 P Eukaryotic translation initiation factor 3 subunit C EIF3C|EIF3S8 protein taxon:9606 20161031 ParkinsonsUK-UCL has_input(UniProtKB:Q04637) UniProtKB:Q99613 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9NYF0 DACT1 involved_in GO:0032091 PMID:18936100 IGI UniProtKB:P35222,UniProtKB:Q9UJU2 P Dapper homolog 1 DACT1|DPR1|HNG3 protein taxon:9606 20170410 ParkinsonsUK-UCL has_input(UniProtKB:Q9UJU2),part_of(GO:0000122),part_of(GO:0090090),occurs_in(GO:0005634)|has_input(UniProtKB:P35222),part_of(GO:0000122),part_of(GO:0090090),occurs_in(GO:0005634) UniProtKB:Q9NYF0 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q9NYF0 DACT1 involved_in GO:0032092 PMID:18936100 IGI UniProtKB:Q13547,UniProtKB:Q9UJU2 P Dapper homolog 1 DACT1|DPR1|HNG3 protein taxon:9606 20170410 ParkinsonsUK-UCL has_input(UniProtKB:Q13547),part_of(GO:0000122),part_of(GO:0090090)|has_input(UniProtKB:Q9UJU2),part_of(GO:0000122),part_of(GO:0090090) UniProtKB:Q9NYF0 `

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

• total: 12

messages

• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB O60260 PRKN involved_in GO:1902283 PMID:22314364 IMP P E3 ubiquitin-protein ligase parkin PRKN|PARK2 protein taxon:9606 20150317 ParkinsonsUK-UCL has_input(CHEBI:18243) UniProtKB:O60260 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P0DMV8 HSPA1A involved_in GO:1902380 PMID:20625543 IDA P Heat shock 70 kDa protein 1A HSPA1A|HSP72|HSPA1|HSX70 protein taxon:9606 20150622 ParkinsonsUK-UCL has_input(UniProtKB:O75460) UniProtKB:P0DMV8 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P55072 VCP involved_in GO:1903007 PMID:22970133 IDA P Transitional endoplasmic reticulum ATPase VCP|HEL-220|HEL-S-70 protein taxon:9606 20140512 ParkinsonsUK-UCL has_input(UniProtKB:P54252) UniProtKB:P55072 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P37840 SNCA involved_in GO:0034599 PMID:23507046 IC GO:1903284 P Alpha-synuclein SNCA|NACP|PARK1 protein taxon:9606 20140811 ParkinsonsUK-UCL UniProtKB:P37840 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P37840 SNCA involved_in GO:1903284 PMID:23507046 IDA P Alpha-synuclein SNCA|NACP|PARK1 protein taxon:9606 20140811 ParkinsonsUK-UCL has_input(UniProtKB:P07203) UniProtKB:P37840 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:1196458 Scarb2 involved_in GO:1905123 PMID:25316793 IMP P Lysosome membrane protein 2 protein taxon:10090 20161025 ParkinsonsUK-UCL occurs_in(UBERON:0000988)|occurs_in(UBERON:0001891) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q8TAX0 OSR1 involved_in GO:1905408 PMID:25531585 IDA P Protein odd-skipped-related 1 OSR1|ODD protein taxon:9606 20160825 ParkinsonsUK-UCL has_input(UniProtKB:P48029) UniProtKB:Q8TAX0 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q9UEW8 STK39 involved_in GO:1905408 PMID:25531585 IDA P STE20/SPS1-related proline-alanine-rich protein kinase STK39|PASK|SPAK protein taxon:9606 20160825 ParkinsonsUK-UCL has_input(UniProtKB:P48029) UniProtKB:Q9UEW8 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q04637 EIF4G1 involved_in GO:1905612 PMID:23409027 IDA P Eukaryotic translation initiation factor 4 gamma 1 EIF4G1|EIF4F|EIF4G|EIF4GI protein taxon:9606 20161028 ParkinsonsUK-UCL has_input(UniProtKB:Q9UKV8),causally_upstream_of(GO:0035278) UniProtKB:Q04637 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q04323 UBXN1 involved_in GO:2000157 PMID:21135095 IDA P UBX domain-containing protein 1 UBXN1|SAKS1 protein taxon:9606 20150611 ParkinsonsUK-UCL has_input(UniProtKB:P54252),part_of(GO:1904293) UniProtKB:Q04323 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q8TAX0 OSR1 involved_in GO:2000650 PMID:25531585 IDA P Protein odd-skipped-related 1 OSR1|ODD protein taxon:9606 20160825 ParkinsonsUK-UCL has_input(UniProtKB:P48029),directly_regulates(GO:0005308) UniProtKB:Q8TAX0 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q9UEW8 STK39 involved_in GO:2000650 PMID:25531585 IDA P STE20/SPS1-related proline-alanine-rich protein kinase STK39|PASK|SPAK protein taxon:9606 20160825 ParkinsonsUK-UCL has_input(UniProtKB:P48029),directly_regulates(GO:0005308) UniProtKB:Q9UEW8 `

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

• total: 7

messages

• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1921256 Dnm1l enables GO:0042803 PMID:20585624 IPI UniProtKB:Q8K1M6 F Dynamin-1-like protein protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 PMID:11564758 IPI UniProtKB:Q9JKY5 F Huntingtin-interacting protein 1-related protein protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 PMID:15533940 IPI UniProtKB:Q9JKY5 F Huntingtin-interacting protein 1-related protein protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 PMID:18790740 IPI UniProtKB:Q9JKY5 F Huntingtin-interacting protein 1-related protein protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 2326 Cebpa enables GO:0042803 PMID:8657121|RGD:1599740 IPI UniProtKB:P05554 F CCAAT/enhancer binding protein alpha gene taxon:10116 20141016 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 619781 Erp29 enables GO:0042803 PMID:9714535|RGD:10047223 IPI UniProtKB:P52555 F endoplasmic reticulum protein 29 gene taxon:10116 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 68397 Syt4 enables GO:0042803 PMID:10397765|RGD:11535116 IPI UniProtKB:P50232 F synaptotagmin 4 gene taxon:10116 20230309 ParkinsonsUK-UCL `

gorule-0000061

Allowed gene product to term relations (gp2term)

• total: 1

messages

• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002432, RO:0001025, RO:0002325. Repaired to RO:0001025--`UniProtKB O95602 POLR1A part_of GO:0000785 PMID:23782956 IMP C DNA-directed RNA polymerase I subunit RPA1 POLR1A protein taxon:9606 20241221 ParkinsonsUK-UCL UniProtKB:O95602 `

gorule-0000065

Annotations to term that are candidates for obsoletion should be removed

• total: 55

messages

• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:1270126 Ulk1 involved_in GO:0018105 PMID:21855797 IDA P Serine/threonine-protein kinase ULK1 protein taxon:10090 20141201 ParkinsonsUK-UCL has_input(UniProtKB:Q91YI1) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:88351 Cdk1 involved_in GO:0018105 GO_REF:0000024 ISS UniProtKB:P06493 P Cyclin-dependent kinase 1 protein taxon:10090 20141006 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:88351 Cdk1 involved_in GO:0018107 GO_REF:0000024 ISS UniProtKB:P06493 P Cyclin-dependent kinase 1 protein taxon:10090 20141006 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:98958 Wnt5a involved_in GO:0043547 PMID:23109420 IDA P Protein Wnt-5a protein taxon:10090 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63001),occurs_in(CL:0000700) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:98958 Wnt5a involved_in GO:0090630 PMID:18953410 IDA P Protein Wnt-5a protein taxon:10090 20151126 ParkinsonsUK-UCL has_input(UniProtKB:P63001),part_of(GO:0071542) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:97805 Ptpn1 acts_upstream_of GO:0043507 PMID:15465829 IMP P Tyrosine-protein phosphatase non-receptor type 1 protein taxon:10090 20210421 ParkinsonsUK-UCL part_of(GO:0034976) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:97806 Ptpn2 involved_in GO:0061099 PMID:21216966 IMP P Tyrosine-protein phosphatase non-receptor type 2 protein taxon:10090 20150226 ParkinsonsUK-UCL part_of(GO:0034976),has_input(PR:000002997),occurs_in(UBERON:0001264) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:103306 Tiam1 involved_in GO:0090630 PMID:23109420 IMP P Rho guanine nucleotide exchange factor TIAM1 protein taxon:10090 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63001),occurs_in(CL:0000700),part_of(GO:2000050) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:106613 Dvl2 involved_in GO:0043547 PMID:23109420 IDA P Segment polarity protein dishevelled homolog DVL-2 protein taxon:10090 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63001) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:109531 Cdc37 involved_in GO:0045859 PMID:21855797 IDA P Hsp90 co-chaperone Cdc37 protein taxon:10090 20151102 ParkinsonsUK-UCL has_input(UniProtKB:O70405) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:2445001 Rab3gap1 involved_in GO:0043547 PMID:16782817 IMP P Rab3 GTPase-activating protein catalytic subunit protein taxon:10090 20140731 ParkinsonsUK-UCL occurs_in(UBERON:0000955),has_input(UniProtKB:P63011) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:2135607 Sirt1 involved_in GO:0043433 PMID:20955178 IMP P NAD-dependent protein deacetylase sirtuin-1 protein taxon:10090 20150121 ParkinsonsUK-UCL has_input(UniProtKB:O35426) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:2180139 Edem1 involved_in GO:0036510 PMID:20065073 IMP P ER degradation-enhancing alpha-mannosidase-like protein 1 protein taxon:10090 20150623 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:1930134 Ern1 involved_in GO:0043507 PMID:10650002 IMP P Serine/threonine-protein kinase/endoribonuclease IRE1 protein taxon:10090 20210421 ParkinsonsUK-UCL part_of(GO:0034976) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:1891731 Stub1 involved_in GO:0051443 PMID:12150907 IDA P E3 ubiquitin-protein ligase CHIP protein taxon:10090 20140813 ParkinsonsUK-UCL has_input(UniProtKB:Q9WVS6) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:1929658 Tbk1 involved_in GO:0018105 PMID:21617041 IDA P Serine/threonine-protein kinase TBK1 protein taxon:10090 20150629 ParkinsonsUK-UCL has_input(UniProtKB:Q8K3K8) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`MGI MGI:1349436 Ern2 involved_in GO:0043507 PMID:10650002 IDA P Serine/threonine-protein kinase/endoribonuclease IRE2 protein taxon:10090 20210421 ParkinsonsUK-UCL part_of(GO:0034976) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RGD 1305769 Pink1 involved_in GO:0018105 PMID:17579517|RGD:8693356 IMP P PTEN induced kinase 1 gene taxon:10116 20151030 ParkinsonsUK-UCL has_input(UniProtKB:Q5XHZ0),part_of(GO:0070301) UniProtKB:D3Z9M9 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RGD 2319 Cdk1 involved_in GO:0018105 GO_REF:0000024|RGD:1600115 ISS UniProtKB:P06493 P cyclin-dependent kinase 1 gene taxon:10116 20140725 ParkinsonsUK-UCL has_input(UniProtKB:Q9H1E3) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RGD 2319 Cdk1 involved_in GO:0018107 GO_REF:0000024|RGD:1600115 ISS UniProtKB:P06493 P cyclin-dependent kinase 1 gene taxon:10116 20140725 ParkinsonsUK-UCL has_input(UniProtKB:Q9H1E3) `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`RGD 61797 Prkn involved_in GO:0033132 GO_REF:0000024|RGD:1600115 ISS UniProtKB:O60260 P parkin RBR E3 ubiquitin protein ligase gene taxon:10116 20140908 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB O14920 IKBKB involved_in GO:0042325 PMID:26212789 IDA P Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB|IKKB protein taxon:9606 20151008 ParkinsonsUK-UCL has_input(UniProtKB:Q96PG8),part_of(GO:0006915) UniProtKB:O14920 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB O75385 ULK1 involved_in GO:0018105 PMID:25126726 IDA P Serine/threonine-protein kinase ULK1 ULK1|KIAA0722 protein taxon:9606 20150629 ParkinsonsUK-UCL has_input(UniProtKB:Q8NFG4) UniProtKB:O75385 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB O75460 ERN1 involved_in GO:0043507 PMID:10650002 IDA P Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1|IRE1 protein taxon:9606 20210421 ParkinsonsUK-UCL part_of(GO:0034976) UniProtKB:O75460 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB O75460 ERN1 involved_in GO:1990579 PMID:21317875 IMP P Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1|IRE1 protein taxon:9606 20180227 ParkinsonsUK-UCL directly_positively_regulates(GO:0004521) UniProtKB:O75460 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB O75928 PIAS2 involved_in GO:0043433 PMID:20408817 IDA P E3 SUMO-protein ligase PIAS2 PIAS2|PIASX protein taxon:9606 20160202 ParkinsonsUK-UCL has_input(UniProtKB:P17861-2) UniProtKB:O75928-1 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P00519 ABL1 involved_in GO:0018108 PMID:10713049 IDA P Tyrosine-protein kinase ABL1 ABL1|ABL|JTK7 protein taxon:9606 20160125 ParkinsonsUK-UCL has_input(UniProtKB:Q05655),part_of(GO:0070301),part_of(GO:1900020) UniProtKB:P00519 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P00519 ABL1 involved_in GO:0018108 PMID:23626584 TAS P Tyrosine-protein kinase ABL1 ABL1|ABL|JTK7 protein taxon:9606 20140901 ParkinsonsUK-UCL has_input(UniProtKB:O60260),part_of(GO:0051444) UniProtKB:P00519 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P00519 ABL1 involved_in GO:0046777 PMID:10713049 IDA P Tyrosine-protein kinase ABL1 ABL1|ABL|JTK7 protein taxon:9606 20160125 ParkinsonsUK-UCL UniProtKB:P00519 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P00519 ABL1 involved_in GO:0051444 PMID:23626584 TAS P Tyrosine-protein kinase ABL1 ABL1|ABL|JTK7 protein taxon:9606 20140901 ParkinsonsUK-UCL has_input(UniProtKB:O60260) UniProtKB:P00519 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P00519 ABL1 involved_in GO:1990051 PMID:10713049 IDA P Tyrosine-protein kinase ABL1 ABL1|ABL|JTK7 protein taxon:9606 20160125 ParkinsonsUK-UCL has_input(UniProtKB:Q05655) UniProtKB:P00519 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P06493 CDK1 involved_in GO:0018105 PMID:11298763 IDA P Cyclin-dependent kinase 1 CDK1|CDC2|CDC28A|CDKN1|P34CDC2 protein taxon:9606 20140723 ParkinsonsUK-UCL has_input(UniProtKB:Q9H1E3) UniProtKB:P06493 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P06493 CDK1 involved_in GO:0018107 PMID:11298763 IDA P Cyclin-dependent kinase 1 CDK1|CDC2|CDC28A|CDKN1|P34CDC2 protein taxon:9606 20140723 ParkinsonsUK-UCL has_input(UniProtKB:Q9H1E3) UniProtKB:P06493 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P08621 SNRNP70 involved_in GO:0043462 PMID:25719862 TAS P U1 small nuclear ribonucleoprotein 70 kDa SNRNP70|RNPU1Z|RPU1|SNRP70|U1AP1 protein taxon:9606 20151007 ParkinsonsUK-UCL UniProtKB:P08621 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P18031 PTPN1 involved_in GO:0061098 PMID:21216966 IDA P Tyrosine-protein phosphatase non-receptor type 1 PTPN1|PTP1B protein taxon:9606 20150226 ParkinsonsUK-UCL part_of(GO:0034976),has_input(PR:000002997),occurs_in(UBERON:0001264) UniProtKB:P18031 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB P63208 SKP1 involved_in GO:1904668 PMID:12820959 IDA P S-phase kinase-associated protein 1 SKP1|EMC19|OCP2|SKP1A|TCEB1L protein taxon:9606 20200227 ParkinsonsUK-UCL UniProtKB:P63208 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q05655 PRKCD involved_in GO:0006468 PMID:10713049 IDA P Protein kinase C delta type PRKCD|PKCD protein taxon:9606 20160125 ParkinsonsUK-UCL has_input(UniProtKB:P00519),part_of(GO:0032147),part_of(GO:0070301) UniProtKB:Q05655 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q05655 PRKCD involved_in GO:0032147 PMID:10713049 IDA P Protein kinase C delta type PRKCD|PKCD protein taxon:9606 20160125 ParkinsonsUK-UCL has_input(UniProtKB:P00519),part_of(GO:0070301) UniProtKB:Q05655 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q13009 TIAM1 involved_in GO:0090630 PMID:23109420 IDA P Rho guanine nucleotide exchange factor TIAM1 TIAM1 protein taxon:9606 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63000) UniProtKB:Q13009 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q13526 PIN1 involved_in GO:0000413 PMID:11533658 TAS P Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 protein taxon:9606 20160114 ParkinsonsUK-UCL UniProtKB:Q13526 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q15042 RAB3GAP1 involved_in GO:0043547 GO_REF:0000024 ISS UniProtKB:Q80UJ7 P Rab3 GTPase-activating protein catalytic subunit RAB3GAP1|KIAA0066|RAB3GAP protein taxon:9606 20140901 ParkinsonsUK-UCL occurs_in(UBERON:0000955),has_input(UniProtKB:P63011) UniProtKB:Q15042 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q3ZAQ7 VMA21 involved_in GO:0043462 PMID:25644398 TAS P Vacuolar ATPase assembly integral membrane protein VMA21 VMA21|MEAX|XMEA protein taxon:9606 20160211 ParkinsonsUK-UCL UniProtKB:Q3ZAQ7 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q8IWQ3 BRSK2 involved_in GO:0043462 PMID:23907667 NAS P Serine/threonine-protein kinase BRSK2 BRSK2|C11orf7|PEN11B|SADA|STK29|HUSSY-12 protein taxon:9606 20150518 ParkinsonsUK-UCL has_input(UniProtKB:P55072) UniProtKB:Q8IWQ3 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q92563 SPOCK2 involved_in GO:0010951 PMID:12810672 TAS P Testican-2 SPOCK2|KIAA0275|TICN2|UNQ269/PRO306 protein taxon:9606 20160817 ParkinsonsUK-UCL has_input(UniProtKB:P51512)|has_input(UniProtKB:P50281) UniProtKB:Q92563 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q92997 DVL3 involved_in GO:0043547 PMID:23109420 IDA P Segment polarity protein dishevelled homolog DVL-3 DVL3|KIAA0208 protein taxon:9606 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P63000) UniProtKB:Q92997 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q96EB6 SIRT1 involved_in GO:0006476 PMID:20955178 IDA P NAD-dependent protein deacetylase sirtuin-1 SIRT1|SIR2L1 protein taxon:9606 20150121 ParkinsonsUK-UCL has_input(UniProtKB:P17861) UniProtKB:Q96EB6 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q96EB6 SIRT1 involved_in GO:0043433 PMID:20955178 IDA P NAD-dependent protein deacetylase sirtuin-1 SIRT1|SIR2L1 protein taxon:9606 20150121 ParkinsonsUK-UCL has_input(UniProtKB:P17861-2) UniProtKB:Q96EB6 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q99683 MAP3K5 involved_in GO:0043507 PMID:23000344 IMP P Mitogen-activated protein kinase kinase kinase 5 MAP3K5|ASK1|MAPKKK5|MEKK5 protein taxon:9606 20150113 ParkinsonsUK-UCL part_of(GO:0034976) UniProtKB:Q99683 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q9BQ16 SPOCK3 involved_in GO:0010951 PMID:12810672 TAS P Testican-3 SPOCK3|TICN3|UNQ409/PRO771 protein taxon:9606 20160817 ParkinsonsUK-UCL UniProtKB:Q9BQ16 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q9BZ23 PANK2 involved_in GO:0016310 PMID:22221393 NAS P Pantothenate kinase 2, mitochondrial PANK2|C20orf48 protein taxon:9606 20150520 ParkinsonsUK-UCL has_input(CHEBI:16454),occurs_in(GO:0005739) UniProtKB:Q9BZ23 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q9NYY3 PLK2 involved_in GO:0018105 PMID:23983262 IDA P Serine/threonine-protein kinase PLK2 PLK2|SNK protein taxon:9606 20151208 ParkinsonsUK-UCL has_input(UniProtKB:P37840) UniProtKB:Q9NYY3 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q9UHD2 TBK1 involved_in GO:0018105 PMID:25803835 IDA P Serine/threonine-protein kinase TBK1 TBK1|NAK protein taxon:9606 20150623 ParkinsonsUK-UCL has_input(UniProtKB:Q14653) UniProtKB:Q9UHD2 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q9UL15 BAG5 involved_in GO:0051438 PMID:24270810 TAS P BAG family molecular chaperone regulator 5 BAG5|KIAA0873 protein taxon:9606 20150422 ParkinsonsUK-UCL UniProtKB:Q9UL15 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q9Y297 BTRC involved_in GO:1904668 PMID:12820959 IDA P F-box/WD repeat-containing protein 1A BTRC|BTRCP|FBW1A|FBXW1A protein taxon:9606 20200227 ParkinsonsUK-UCL UniProtKB:Q9Y297 `
• WARNING - Violates GO Rule:GORULE:0000065: Annotations to term that are candidates for obsoletion should be removed--`UniProtKB Q9Y376 CAB39 involved_in GO:0071902 PMID:19892943 IDA P Calcium-binding protein 39 CAB39|MO25|CGI-66 protein taxon:9606 20141029 ParkinsonsUK-UCL UniProtKB:Q9Y376 `