GORULE violations assigned by ParkinsonsUK-UCL

Contents

gorule-0000005 IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

gorule-0000020 Automatic repair of annotations to merged or obsoleted terms

gorule-0000039 Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

gorule-0000046 The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

gorule-0000061 Allowed gene product to term relations (gp2term)

MESSAGES

gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

• total: 1

messages

• WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`RGD 621808 Park7 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q99497 F Parkinson disease protein 7 homolog Cap1|Park7 protein taxon:10116 20210910 ParkinsonsUK-UCL `

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

• total: 11

messages

• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:1914217 Edem3 involved_in GO:0006058 PMID:16431915 IDA P ER degradation-enhancing alpha-mannosidase-like protein 3 Edem3 protein taxon:10090 20231121 ParkinsonsUK-UCL part_of(GO:0036503) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`MGI MGI:1914217 mEDEM3 involved_in GO:0006058 PMID:16431915 IDA P ER degradation-enhancing alpha-mannosidase-like protein 3 (mouse) alpha-1,2-mannosidase EDEM3 (mouse)|mEDEM3 protein taxon:10090 20231121 ParkinsonsUK-UCL part_of(GO:0036503) `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q92611 EDEM1 involved_in GO:0006058 PMID:25092655 IMP P ER degradation-enhancing alpha-mannosidase-like protein 1 EDEM1|EDEM|KIAA0212 protein taxon:9606 20231121 ParkinsonsUK-UCL part_of(GO:0036503) UniProtKB:Q92611 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q9BV94 EDEM2 involved_in GO:0006058 PMID:25092655 IMP P ER degradation-enhancing alpha-mannosidase-like protein 2 EDEM2|C20orf31|C20orf49|UNQ573/PRO1135 protein taxon:9606 20231121 ParkinsonsUK-UCL part_of(GO:0036503) UniProtKB:Q9BV94 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q9BZQ6 EDEM3 involved_in GO:0006058 PMID:25092655 IMP P ER degradation-enhancing alpha-mannosidase-like protein 3 EDEM3|C1orf22 protein taxon:9606 20231121 ParkinsonsUK-UCL part_of(GO:0036503) UniProtKB:Q9BZQ6 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q9UKM7 MAN1B1 involved_in GO:0006058 PMID:10521544 IDA P Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1|UNQ747/PRO1477 protein taxon:9606 20231121 ParkinsonsUK-UCL part_of(GO:0036503) UniProtKB:Q9UKM7 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q9UKM7 MAN1B1 involved_in GO:0006058 PMID:18003979 IMP P Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1|UNQ747/PRO1477 protein taxon:9606 20231121 ParkinsonsUK-UCL UniProtKB:Q9UKM7 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB A0A8V0YJ07 EDEM3 involved_in GO:0006058 PMID:25092655 IMP P alpha-1,2-Mannosidase EDEM3 protein taxon:9031 20250115 ParkinsonsUK-UCL part_of(GO:0036503) UniProtKB:A0A8V0YJ07 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB A0A8V1A1A6 EDEM2 involved_in GO:0006058 PMID:25092655 IMP P alpha-1,2-Mannosidase EDEM2 protein taxon:9031 20250115 ParkinsonsUK-UCL part_of(GO:0036503) UniProtKB:A0A8V1A1A6 `
• ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB A0A8V1ABV1 MAN1B1 involved_in GO:0006058 PMID:25092655 IMP P alpha-1,2-Mannosidase MAN1B1 protein taxon:9031 20250115 ParkinsonsUK-UCL part_of(GO:0036503) UniProtKB:A0A8V1ABV1 `
• WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P55072 VCP involved_in GO:0006734 PMID:23498975 IMP P Transitional endoplasmic reticulum ATPase VCP|HEL-220|HEL-S-70 protein taxon:9606 20150622 ParkinsonsUK-UCL has_input(CHEBI:16908) UniProtKB:P55072 `

gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

• total: 1

messages

• ERROR - Violates GO Rule:GORULE:0000039: Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants--`ComplexPortal CPX-263 nsfl1c-vcp_rat part_of GO:1990730 PMID:9214505 IDA C Vcp-Nsfl1c AAA ATPase complex 3xNsfl1c:6xVcp|p47-VCP complex|NSFL1-VCP complex|NSFL1-p97 complex|p47-p97 complex|NSFL1C-p97 complex protein_complex taxon:10116 20180219 ParkinsonsUK-UCL `

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

• total: 12

messages

• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 PMID:11564758 IPI UniProtKB:Q9JKY5 F Huntingtin-interacting protein 1-related protein Hip1r protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 PMID:15533940 IPI UniProtKB:Q9JKY5 F Huntingtin-interacting protein 1-related protein Hip1r protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 Hip1r enables GO:0042803 PMID:18790740 IPI UniProtKB:Q9JKY5 F Huntingtin-interacting protein 1-related protein Hip1r protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 mHIP1R enables GO:0042803 PMID:11564758 IPI UniProtKB:Q9JKY5 F huntingtin-interacting protein 1-related protein (mouse) HIP1-related protein (mouse)|mHIP1R protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 mHIP1R enables GO:0042803 PMID:15533940 IPI UniProtKB:Q9JKY5 F huntingtin-interacting protein 1-related protein (mouse) HIP1-related protein (mouse)|mHIP1R protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1352504 mHIP1R enables GO:0042803 PMID:18790740 IPI UniProtKB:Q9JKY5 F huntingtin-interacting protein 1-related protein (mouse) HIP1-related protein (mouse)|mHIP1R protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1921256 Dnm1l enables GO:0042803 PMID:20585624 IPI UniProtKB:Q8K1M6 F Dynamin-1-like protein Dnm1l|Drp1 protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1921256 mDNM1L enables GO:0042803 PMID:20585624 IPI UniProtKB:Q8K1M6 F dynamin-1-like protein (mouse) dymple (mouse)|dynamin family member proline-rich carboxyl-terminal domain less (mouse)|dynamin-related protein 1 (mouse)|mDNM1L protein taxon:10090 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 2326 Cebpa enables GO:0042803 PMID:8657121 IPI UniProtKB:P05554 F CCAAT/enhancer-binding protein alpha Cebpa protein taxon:10116 20141016 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 619781 Erp29 enables GO:0042803 PMID:9714535 IPI UniProtKB:P52555 F Endoplasmic reticulum resident protein 29 Erp29 protein taxon:10116 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 68397 Syt4 enables GO:0042803 PMID:10397765 IPI UniProtKB:P50232 F Synaptotagmin-4 Syt4 protein taxon:10116 20230309 ParkinsonsUK-UCL `
• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`SGD S000003924 DNM1 involved_in GO:0051260 PMID:21170049 IDA P dynamin-related GTPase DNM1 DRP1|YLL001W protein taxon:559292 20170207 ParkinsonsUK-UCL `

gorule-0000061

Allowed gene product to term relations (gp2term)

• total: 1

messages

• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002432, RO:0001025, RO:0002325. Repaired to RO:0001025--`UniProtKB O95602 POLR1A part_of GO:0000785 PMID:23782956 IMP C DNA-directed RNA polymerase I subunit RPA1 POLR1A protein taxon:9606 20241221 ParkinsonsUK-UCL UniProtKB:O95602 `