GORULE violations assigned by DisProt

Contents

gorule-0000006 IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC

gorule-0000008 No annotations should be made to uninformative high level terms

gorule-0000027 Each identifier in GAF is valid

gorule-0000046 The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

gorule-0000061 Allowed gene product to term relations (gp2term)

MESSAGES

gorule-0000006

IEP and HEP usage is restricted to terms from the Biological Process ontology, except when assigned by GOC

• total: 11

messages

• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB O14672 ADAM10 enables GO:0042803 PMID:25349418 IEP F Disintegrin and metalloproteinase domain-containing protein 10 ADAM10|KUZ|MADM protein taxon:9606 20220228 DisProt has_input(UniProtKB:O14672) UniProtKB:O14672 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB O75807 PPP1R15A enables GO:0019888 PMID:34847777 IEP F Protein phosphatase 1 regulatory subunit 15A PPP1R15A|GADD34 protein taxon:9606 20220228 DisProt has_input(UniProtKB:P62136) UniProtKB:O75807 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P01106 MYC enables GO:0140537 PMID:8755740 IEP F Myc proto-oncogene protein MYC|BHLHE39 protein taxon:9606 20220228 DisProt UniProtKB:P01106 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P18564 ITGB6 enables GO:0140677 PMID:11821050 IEP F Integrin beta-6 ITGB6 protein taxon:9606 20220228 DisProt UniProtKB:P18564 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P40337 VHL enables GO:0003714 PMID:11641274 IEP F von Hippel-Lindau disease tumor suppressor VHL protein taxon:9606 20220228 DisProt UniProtKB:P40337 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P46379 BAG6 enables GO:0140677 PMID:25713138 IEP F Large proline-rich protein BAG6 BAG6|BAT3|G3 protein taxon:9606 20220228 DisProt UniProtKB:P46379 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q06787 FMR1 enables GO:0008143 PMID:10496225 IEP F Fragile X messenger ribonucleoprotein 1 FMR1 protein taxon:9606 20220228 DisProt UniProtKB:Q06787 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q06787 FMR1 enables GO:0008266 PMID:10496225 IEP F Fragile X messenger ribonucleoprotein 1 FMR1 protein taxon:9606 20220228 DisProt UniProtKB:Q06787 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q06787 FMR1 enables GO:0034046 PMID:10496225 IEP F Fragile X messenger ribonucleoprotein 1 FMR1 protein taxon:9606 20220228 DisProt UniProtKB:Q06787 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB Q16236 NFE2L2 enables GO:0031625 PMID:16888629 IEP F Nuclear factor erythroid 2-related factor 2 NFE2L2|NRF2 protein taxon:9606 20220228 DisProt has_input(UniProtKB:Q14145) UniProtKB:Q16236 `
• ERROR - Violates GO Rule:GORULE:0000006: IEP and HEP usage is restricted to terms from the Biological Process ontology--`UniProtKB P06836 GAP43 enables GO:0008289 PMID:1826685 IEP F Neuromodulin GAP43 protein taxon:9913 20220228 DisProt UniProtKB:P06836 `

gorule-0000008

No annotations should be made to uninformative high level terms

• total: 9

messages

• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P35637 FUS is_active_in GO:0043232 PMID:21541367 IDA C RNA-binding protein FUS FUS|TLS protein taxon:9606 20220228 DisProt UniProtKB:P35637 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P35637 FUS is_active_in GO:0043232 PMID:22579281 IDA C RNA-binding protein FUS FUS|TLS protein taxon:9606 20220228 DisProt UniProtKB:P35637 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P35637 FUS is_active_in GO:0043232 PMID:26317470 IDA C RNA-binding protein FUS FUS|TLS protein taxon:9606 20220228 DisProt UniProtKB:P35637 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P38398 BRCA1 is_active_in GO:0043232 PMID:9008167 IDA C Breast cancer type 1 susceptibility protein BRCA1|RNF53 protein taxon:9606 20220228 DisProt UniProtKB:P38398 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB P40337 VHL is_active_in GO:0043232 PMID:14963040 EXP C von Hippel-Lindau disease tumor suppressor VHL protein taxon:9606 20220228 DisProt UniProtKB:P40337 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q06787 FMR1 is_active_in GO:0043232 PMID:30765518 IDA C Fragile X messenger ribonucleoprotein 1 FMR1 protein taxon:9606 20220228 DisProt UniProtKB:Q06787 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13148 TARDBP is_active_in GO:0043232 PMID:26735904 EXP C TAR DNA-binding protein 43 TARDBP|TDP43 protein taxon:9606 20220228 DisProt UniProtKB:Q13148 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13148 TARDBP is_active_in GO:0043232 PMID:26735904 IDA C TAR DNA-binding protein 43 TARDBP|TDP43 protein taxon:9606 20220228 DisProt UniProtKB:Q13148 `
• WARNING - Violates GO Rule:GORULE:0000008: No annotations should be made to uninformatively high level terms--`UniProtKB Q13148 TARDBP is_active_in GO:0043232 PMID:28988034 IDA C TAR DNA-binding protein 43 TARDBP|TDP43 protein taxon:9606 20220228 DisProt UniProtKB:Q13148 `

gorule-0000027

Each identifier in GAF is valid

• total: 8

messages

• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB O60568 PLOD3 enables GO:0036094 PMID:30089812 EXP F Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 PLOD3 protein taxon:9606 20220228 DisProt has_input(ChEBI:17659) UniProtKB:O60568 `
• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB O60568 PLOD3 enables GO:0046872 PMID:30089812 EXP F Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 PLOD3 protein taxon:9606 20220228 DisProt has_input(ChEBI:29033),has_input(ChEBI:29035) UniProtKB:O60568 `
• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB O60568 PLOD3 enables GO:0046872 PMID:30089812 EXP F Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 PLOD3 protein taxon:9606 20220228 DisProt has_input(ChEBI:29033),has_input(ChEBI:29035) UniProtKB:O60568 `
• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB A0A1D5PXA5 TRPV4 enables GO:0008289 PMID:37443299 EXP F Transient receptor potential cation channel subfamily V member 4 TRPV4 protein taxon:9031 20220228 DisProt has_input(ChEBI:34080) UniProtKB:A0A1D5PXA5 `
• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB A0A1D5PXA5 TRPV4 enables GO:0008289 PMID:37443299 IPI ChEBI:34080,ChEBI:73001 F Transient receptor potential cation channel subfamily V member 4 TRPV4 protein taxon:9031 20220228 DisProt UniProtKB:A0A1D5PXA5 `
• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB O15431 SLC31A1 enables GO:0005507 PMID:36409899 EXP F High affinity copper uptake protein 1 SLC31A1|COPT1|CTR1 protein taxon:9606 20220228 DisProt has_input(ChEBI:49552) UniProtKB:O15431 `
• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB A0A1D5PXA5 TRPV4 enables GO:0008289 PMID:37443299 IPI ChEBI:34080,ChEBI:73001 F Transient receptor potential cation channel subfamily V member 4 TRPV4 protein taxon:9031 20220228 DisProt UniProtKB:A0A1D5PXA5 `
• WARNING - Invalid identifier:GORULE:0000027: ChEBI not found in list of database names in dbxrefs--`UniProtKB O00499 BIN1 enables GO:0008289 PMID:18658220 EXP F Myc box-dependent-interacting protein 1 BIN1|AMPHL protein taxon:9606 20220228 DisProt has_input(ChEBI:78018) UniProtKB:O00499 `

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

• total: 1

messages

• WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P80723 BASP1 involved_in GO:0051260 PMID:32750402 IDA P Brain acid soluble protein 1 BASP1|NAP22 protein taxon:9606 20220228 DisProt UniProtKB:P80723 `

gorule-0000061

Allowed gene product to term relations (gp2term)

• total: 5

messages

• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB O43561 LAT is_active_in GO:0036398 PMID:33080222 IDA C Linker for activation of T-cells family member 1 LAT protein taxon:9606 20220228 DisProt UniProtKB:O43561-2 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB O75807 PPP1R15A is_active_in GO:0000164 PMID:34847777 IPI UniProtKB:P62136,UniProtKB:Q9BY44 C Protein phosphatase 1 regulatory subunit 15A PPP1R15A|GADD34 protein taxon:9606 20220228 DisProt UniProtKB:O75807 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB P38936 CDKN1A is_active_in GO:0070557 PMID:11463845 IPI UniProtKB:P12004 C Cyclin-dependent kinase inhibitor 1 CDKN1A|CAP20|CDKN1|CIP1|MDA6|PIC1|SDI1|WAF1 protein taxon:9606 20220228 DisProt UniProtKB:P38936 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB Q16236 NFE2L2 is_active_in GO:0016592 PMID:32727915 EXP C Nuclear factor erythroid 2-related factor 2 NFE2L2|NRF2 protein taxon:9606 20220228 DisProt UniProtKB:Q16236 `
• WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB Q92574 TSC1 is_active_in GO:0033596 PMID:26893383 EXP C Hamartin TSC1|KIAA0243|TSC protein taxon:9606 20220228 DisProt UniProtKB:Q92574 `