GORULE violations assigned by BHF-UCL

gorule-0000001 GAF lines are parsed according to GAF 2.2 specifications

gorule-0000005 IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

gorule-0000013 Taxon-appropriate annotation check

gorule-0000015 Dual species taxon check

gorule-0000016 With/From: IC annotations require a With/From GO ID

gorule-0000020 Automatic repair of annotations to merged or obsoleted terms

gorule-0000027 Each identifier in GAF is valid

gorule-0000039 Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

gorule-0000046 The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

gorule-0000061 Allowed gene product to term relations (gp2term)

MESSAGES

gorule-0000001

GAF lines are parsed according to GAF 2.2 specifications

total: 22

messages

WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00001B8558_9606 URS00001B8558_9606 involved_in GO:0042593 GO_REF:0000024 ISS RNAcentral:URS00001B8558_10090 P miR-122 from Homo sapiens (PDB 7KI3, chain B) misc_RNA taxon:9606 20180608 BHF-UCL occurs_in(CL:0000182) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00001B8558_9606 URS00001B8558_9606 involved_in GO:0042632 GO_REF:0000024 ISS RNAcentral:URS00001B8558_10090 P miR-122 from Homo sapiens (PDB 7KI3, chain B) misc_RNA taxon:9606 20180608 BHF-UCL occurs_in(CL:0000182) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00001B8558_9606 URS00001B8558_9606 involved_in GO:0045723 GO_REF:0000024 ISS RNAcentral:URS00001B8558_10090 P miR-122 from Homo sapiens (PDB 7KI3, chain B) misc_RNA taxon:9606 20180608 BHF-UCL occurs_in(CL:0000182) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00001B8558_9606 URS00001B8558_9606 involved_in GO:0046322 GO_REF:0000024 ISS RNAcentral:URS00001B8558_10090 P miR-122 from Homo sapiens (PDB 7KI3, chain B) misc_RNA taxon:9606 20180608 BHF-UCL occurs_in(CL:0000182) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00001B8558_9606 URS00001B8558_9606 involved_in GO:0070328 GO_REF:0000024 ISS RNAcentral:URS00001B8558_10090 P miR-122 from Homo sapiens (PDB 7KI3, chain B) misc_RNA taxon:9606 20180608 BHF-UCL occurs_in(CL:0000182) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00001B8558_9606 URS00001B8558_9606 involved_in GO:0106120 GO_REF:0000024 ISS RNAcentral:URS00001B8558_10090 P miR-122 from Homo sapiens (PDB 7KI3, chain B) misc_RNA taxon:9606 20180608 BHF-UCL occurs_in(CL:0000182) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 enables GO:1903231 PMID:19949084 IDA F Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20160211 BHF-UCL has_input(UniProtKB:P05362) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 enables GO:1903231 PMID:23258273 IDA F Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20180111 BHF-UCL has_input(UniProtKB:P35968) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:0010629 PMID:23258273 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20180111 BHF-UCL has_input(UniProtKB:P24385),occurs_in(CL:0002618) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:0035195 PMID:19949084 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20170807 BHF-UCL has_input(UniProtKB:P05362),part_of(GO:0071356),negatively_regulates(GO:0061756) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:0035195 PMID:23258273 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20180111 BHF-UCL has_input(UniProtKB:P35968),occurs_in(CL:0002618) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:0045930 PMID:23258273 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20180111 BHF-UCL occurs_in(CL:0002618) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:0050728 PMID:19949084 IC GO:1904995 P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20160311 BHF-UCL `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:0071356 PMID:19949084 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20160211 BHF-UCL `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:0090051 PMID:23258273 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20180111 BHF-UCL occurs_in(CL:0002618) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:1904995 PMID:19949084 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20160311 BHF-UCL part_of(GO:0071356) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS0000460483_9606 URS0000460483_9606 involved_in GO:1905563 PMID:23258273 IDA P Homo sapiens (human) microRNA miR-17 sRNA taxon:9606 20180111 BHF-UCL results_in_division_of(CL:0002618) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00007E4AF8_9606 URS00007E4AF8_9606 enables GO:0035198 PMID:34454184 IDA F Homo sapiens (human) myocardial infarction associated transcript (MIAT) sRNA taxon:9606 20220503 BHF-UCL has_input(RNAcentral:URS0000355E82_9606),occurs_in(CL:0000235) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00007E4AF8_9606 URS00007E4AF8_9606 enables GO:0140869 PMID:34454184 IDA F Homo sapiens (human) myocardial infarction associated transcript (MIAT) sRNA taxon:9606 20230223 BHF-UCL has_input(RNAcentral:URS0000355E82_9606),occurs_in(CL:0000235),part_of(GO:0000512) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00007E4AF8_9606 URS00007E4AF8_9606 involved_in GO:0000512 PMID:34454184 IDA P Homo sapiens (human) myocardial infarction associated transcript (MIAT) sRNA taxon:9606 20230223 BHF-UCL has_input(RNAcentral:URS0000355E82_9606) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00007E4AF8_9606 URS00007E4AF8_9606 involved_in GO:0042742 PMID:34454184 IDA P Homo sapiens (human) myocardial infarction associated transcript (MIAT) sRNA taxon:9606 20230223 BHF-UCL occurs_in(CL:0000235) `
WARNING - Invalid subject type:defaulting to 'gene_product'--`RNAcentral URS00007E4AF8_9606 URS00007E4AF8_9606 involved_in GO:2000111 PMID:34454184 IMP P Homo sapiens (human) myocardial infarction associated transcript (MIAT) sRNA taxon:9606 20230223 BHF-UCL occurs_in(CL:0000235),part_of(GO:0042742) `

gorule-0000005

IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations are not allowed for direct annotations to to 'protein binding ; GO:0005515 or GO:0005488 binding''

total: 8

messages

WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI MGI:1277959 Dlg4 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:P31016 F discs large MAGUK scaffold protein 4 Dlgh4|PSD-95|PSD95|SAP90|SAP90A protein taxon:10090 20131017 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`MGI MGI:3613677 Shank1 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9WV48 F SH3 and multiple ankyrin repeat domains 1 protein taxon:10090 20131017 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q92974 ARHGEF2 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q865S3 F Rho guanine nucleotide exchange factor 2 ARHGEF2|KIAA0651|LFP40 protein taxon:9606 20210910 BHF-UCL UniProtKB:Q92974 `
WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9BYB0 SHANK3 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q4ACU6 F SH3 and multiple ankyrin repeat domains protein 3 SHANK3|KIAA1650|PROSAP2|PSAP2 protein taxon:9606 20110218 BHF-UCL UniProtKB:Q9BYB0 `
WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9BYB0 SHANK3 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9JLU4 F SH3 and multiple ankyrin repeat domains protein 3 SHANK3|KIAA1650|PROSAP2|PSAP2 protein taxon:9606 20131017 BHF-UCL UniProtKB:Q9BYB0 `
WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9NQC8 IFT46 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:A2T2X4 F Intraflagellar transport protein 46 homolog IFT46|C11orf2|C11orf60 protein taxon:9606 20110314 BHF-UCL UniProtKB:Q9NQC8 `
WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9Y366 IFT52 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q946G4 F Intraflagellar transport protein 52 homolog IFT52|C20orf9|NGD5|CGI-53 protein taxon:9606 20110314 BHF-UCL UniProtKB:Q9Y366 `
WARNING - Violates GO Rule:GORULE:0000005: IEA, ISS, ISO, ISM, ISA, IBA, RCA annotations ae not allowed for direct annotations to 'binding ; GO:0005488' or 'protein binding ; GO:0005515'--`UniProtKB Q9Y566 SHANK1 enables GO:0005515 GO_REF:0000024 ISS UniProtKB:Q9WV48 F SH3 and multiple ankyrin repeat domains protein 1 SHANK1 protein taxon:9606 20131017 BHF-UCL UniProtKB:Q9Y566 `

gorule-0000013

Taxon-appropriate annotation check

total: 1

messages

WARNING - Violates GO Rule:GORULE:0000013: Taxon-appropriate annotation check--`FB FBgn0259174 Nedd4 involved_in GO:1905062 PMID:28246214 IMP P Nedd4 ACN62428.1|CG32184|CG42279|CG7555|DNedd4|NEDD4|dNedd4|dNedd4-1|nedd4 protein taxon:7227 20170530 BHF-UCL `

gorule-0000015

Dual species taxon check

total: 2

messages

WARNING - Violates GO Rule:GORULE:0000015: Dual species taxon check--`UniProtKB P46934 NEDD4 acts_upstream_of GO:0046755 PMID:15126635 IMP P E3 ubiquitin-protein ligase NEDD4 NEDD4|KIAA0093|NEDD4-1|RPF1|PIG53 protein taxon:9606|taxon:11926 20200203 BHF-UCL UniProtKB:P46934 `
WARNING - Violates GO Rule:GORULE:0000015: Dual species taxon check--`UniProtKB Q92692 NECTIN2 involved_in GO:0019064 PMID:12915581 IDA P Nectin-2 NECTIN2|HVEB|PRR2|PVRL2 protein taxon:9606|taxon:10310 20081128 BHF-UCL UniProtKB:Q92692 `

gorule-0000016

With/From: IC annotations require a With/From GO ID

total: 5

messages

WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`MGI MGI:97362 Nos3 located_in GO:0005737 PMID:11732991 IC GO:0005737 C nitric oxide synthase 3, endothelial cell 2310065A03Rik|Nos-3|eNOS|ecNOS protein taxon:10090 20180821 BHF-UCL part_of(CL:0000115),part_of(UBERON:0011742),existence_overlaps(GO:0003180) `
WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P14859 POU2F1 enables GO:0001228 PMID:25802280 IC F POU domain, class 2, transcription factor 1 POU2F1|OCT1|OTF1 protein taxon:9606 20220817 BHF-UCL part_of(GO:1902895),has_input(RNAcentral:URS00001DC04F_9606) UniProtKB:P14859 `
WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P14859 POU2F1 involved_in GO:1902895 PMID:25802280 IC P POU domain, class 2, transcription factor 1 POU2F1|OCT1|OTF1 protein taxon:9606 20220817 BHF-UCL has_input(RNAcentral:URS00001DC04F_9606) UniProtKB:P14859 `
WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P55317 FOXA1 enables GO:0001228 PMID:25802280 IC F Hepatocyte nuclear factor 3-alpha FOXA1|HNF3A|TCF3A protein taxon:9606 20220817 BHF-UCL has_input(RNAcentral:URS00001DC04F_9606),part_of(GO:1902895) UniProtKB:P55317 `
WARNING - Violates GO Rule:GORULE:0000016: All IC annotations should include a GO ID in the "With/From" column that is also different from the entry in the "GO ID" column--`UniProtKB P55317 FOXA1 involved_in GO:1902895 PMID:25802280 IC P Hepatocyte nuclear factor 3-alpha FOXA1|HNF3A|TCF3A protein taxon:9606 20220817 BHF-UCL has_input(RNAcentral:URS00001DC04F_9606) UniProtKB:P55317 `

gorule-0000020

Automatic repair of annotations to merged or obsoleted terms

total: 17

messages

ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q10471 GALNT2 involved_in GO:0018242 PMID:12438318 IDA P Polypeptide N-acetylgalactosaminyltransferase 2 GALNT2 protein taxon:9606 20241027 BHF-UCL has_input(PR:000050032),part_of(GO:0051604) UniProtKB:Q10471 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q10471 GALNT2 involved_in GO:0018242 PMID:9295285 IDA P Polypeptide N-acetylgalactosaminyltransferase 2 GALNT2 protein taxon:9606 20080306 BHF-UCL UniProtKB:Q10471 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q10472 GALNT1 involved_in GO:0018242 PMID:9295285 IDA P Polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 protein taxon:9606 20080306 BHF-UCL UniProtKB:Q10472 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q14435 GALNT3 involved_in GO:0018242 PMID:9295285 IDA P Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 protein taxon:9606 20080306 BHF-UCL UniProtKB:Q14435 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q10471 GALNT2 involved_in GO:0018243 PMID:12438318 IDA P Polypeptide N-acetylgalactosaminyltransferase 2 GALNT2 protein taxon:9606 20241027 BHF-UCL has_input(PR:000050032),part_of(GO:0051604) UniProtKB:Q10471 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q10471 GALNT2 involved_in GO:0018243 PMID:9295285 IDA P Polypeptide N-acetylgalactosaminyltransferase 2 GALNT2 protein taxon:9606 20080306 BHF-UCL UniProtKB:Q10471 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q10472 GALNT1 involved_in GO:0018243 PMID:9295285 IDA P Polypeptide N-acetylgalactosaminyltransferase 1 GALNT1 protein taxon:9606 20080306 BHF-UCL UniProtKB:Q10472 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q14435 GALNT3 involved_in GO:0018243 PMID:9295285 IDA P Polypeptide N-acetylgalactosaminyltransferase 3 GALNT3 protein taxon:9606 20080306 BHF-UCL UniProtKB:Q14435 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q11206 ST3GAL4 enables GO:0047288 PMID:8288606 IDA F CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ST3GAL4|CGS23|NANTA3|SIAT4C|STZ protein taxon:9606 20170803 BHF-UCL part_of(GO:0009247),part_of(GO:0030259),part_of(GO:0097503),has_input(CHEBI:27938),has_output(CHEBI:78568)|part_of(GO:0009247),part_of(GO:0030259),part_of(GO:0097503),has_input(CHEBI:77709),has_output(CHEBI:78445) UniProtKB:Q11206 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q11206 ST3GAL4 involved_in GO:0030259 PMID:8288606 IDA P CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ST3GAL4|CGS23|NANTA3|SIAT4C|STZ protein taxon:9606 20170803 BHF-UCL part_of(GO:0009247),has_input(CHEBI:27938),has_output(CHEBI:78568)|part_of(GO:0009247),has_input(CHEBI:77709),has_output(CHEBI:78445) UniProtKB:Q11206 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q11206 ST3GAL4 involved_in GO:0097503 PMID:8288606 IDA P CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ST3GAL4|CGS23|NANTA3|SIAT4C|STZ protein taxon:9606 20170803 BHF-UCL part_of(GO:0009247),part_of(GO:0030259),has_input(CHEBI:27938),has_output(CHEBI:78568)|part_of(GO:0009247),part_of(GO:0030259),has_input(CHEBI:77709),has_output(CHEBI:78445) UniProtKB:Q11206 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q16842 ST3GAL2 enables GO:0047288 PMID:9266697 IDA F CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 ST3GAL2|SIAT4B protein taxon:9606 20170803 BHF-UCL has_input(CHEBI:27938),part_of(GO:0097503),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:78568)|has_input(CHEBI:87785),part_of(GO:0097503),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:78452)|has_input(CHEBI:82939),part_of(GO:0097503),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:82940)|has_input(CHEBI:88069),part_of(GO:0097503),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:90151)|has_input(CHEBI:82639),part_of(GO:0097503),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:82637)|has_input(CHEBI:77709),part_of(GO:0097503),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:78445) UniProtKB:Q16842 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q16842 ST3GAL2 involved_in GO:0030259 PMID:9266697 IDA P CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 ST3GAL2|SIAT4B protein taxon:9606 20170803 BHF-UCL has_input(CHEBI:27938),part_of(GO:0009247),has_output(CHEBI:78568)|has_input(CHEBI:87785),part_of(GO:0009247),has_output(CHEBI:78452)|has_input(CHEBI:82939),part_of(GO:0009247),has_output(CHEBI:82940)|has_input(CHEBI:88069),part_of(GO:0009247),has_output(CHEBI:90151)|has_input(CHEBI:82639),part_of(GO:0009247),has_output(CHEBI:82637)|has_input(CHEBI:77709),part_of(GO:0009247),has_output(CHEBI:78445) UniProtKB:Q16842 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB Q16842 ST3GAL2 involved_in GO:0097503 PMID:9266697 IDA P CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 ST3GAL2|SIAT4B protein taxon:9606 20170803 BHF-UCL has_input(CHEBI:27938),part_of(GO:0009247),part_of(GO:0030259),has_output(CHEBI:78568)|has_input(CHEBI:87785),part_of(GO:0009247),part_of(GO:0030259),has_output(CHEBI:78452)|has_input(CHEBI:82939),part_of(GO:0009247),part_of(GO:0030259),has_output(CHEBI:82940)|part_of(GO:0009247),part_of(GO:0030259),has_input(CHEBI:88069),has_output(CHEBI:90151)|has_input(CHEBI:82639),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:82637)|has_input(CHEBI:77709),part_of(GO:0030259),part_of(GO:0009247),has_output(CHEBI:78445) UniProtKB:Q16842 `
ERROR - Obsolete class with no replacement:Violates GORULE:0000020--`UniProtKB P06400 RB1 involved_in GO:0090230 PMID:20551165 TAS P Retinoblastoma-associated protein RB1 protein taxon:9606 20110307 BHF-UCL UniProtKB:P06400 `
WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB P41134 ID1 involved_in GO:0010621 PMID:14522471 TAS P DNA-binding protein inhibitor ID-1 ID1|BHLHB24|ID protein taxon:9606 20090114 BHF-UCL UniProtKB:P41134 `
WARNING - Obsolete class:Violates GORULE:0000020, but was repaired--`UniProtKB Q03014 HHEX involved_in GO:0010621 PMID:18713067 IC GO:0034504 P Hematopoietically-expressed homeobox protein HHEX HHEX|HEX|PRH|PRHX protein taxon:9606 20100218 BHF-UCL UniProtKB:Q03014 `

gorule-0000027

Each identifier in GAF is valid

total: 2

messages

WARNING - Invalid identifier:GORULE:0000027: ZDB-PUB-150609-8 does not match any id_syntax patterns for ZFIN in dbxrefs--`ZFIN ZDB-GENE-040611-1 nrp1b involved_in GO:0051491 PMID:26051942|ZFIN:ZDB-PUB-150609-8 IGI ZFIN:ZDB-GENE-030519-2 P neuropilin 1b protein_coding_gene taxon:7955 20170726 BHF-UCL part_of(GO:0007229)|part_of(GO:0090050)|part_of(GO:0038189) `
WARNING - Invalid identifier:GORULE:0000027: ZDB-PUB-150609-8 does not match any id_syntax patterns for ZFIN in dbxrefs--`ZFIN ZDB-GENE-040611-1 nrp1b involved_in GO:0090050 PMID:26051942|ZFIN:ZDB-PUB-150609-8 IGI ZFIN:ZDB-GENE-030519-2 P neuropilin 1b protein_coding_gene taxon:7955 20170726 BHF-UCL part_of(GO:0038189)|part_of(GO:0007229) `

gorule-0000039

Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants

total: 1

messages

ERROR - Violates GO Rule:GORULE:0000039: Protein complexes can not be annotated to GO:0032991 (protein-containing complex) or its descendants--`ComplexPortal CPX-19 tert-terc_mouse part_of GO:0000333 PMID:16037417 IMP C Telomerase catalytic core complex 2xTert:2xTerc protein_complex taxon:10090 20150217 BHF-UCL `

gorule-0000046

The ‘with’ field (GAF column 8) must be the same as the gene product (GAF column 2) when annotating to ‘self-binding’ terms.

total: 88

messages

WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:103577 Hand1 enables GO:0042803 PMID:10924525 IPI UniProtKB:Q64279 F heart and neural crest derivatives expressed 1 Ehand1|Hxt|Th1|Thing1|bHLHa27|eHAND protein taxon:10090 20090826 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:103580 Hand2 enables GO:0042803 PMID:11812799 IPI UniProtKB:Q61039 F heart and neural crest derivatives expressed 2 Ehand2|Hed|Thing2|bHLHa26|dHAND protein taxon:10090 20090827 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:104593 Xcl1 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:P47992 F chemokine (C motif) ligand 1 ATAC|LTN|Lptn|SCM-1|SCM-1a|Scyc1|lymphotactin protein taxon:10090 20110403 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:108050 Ext2 enables GO:0042803 PMID:10639137 IDA F exostosin glycosyltransferase 2 protein taxon:10090 20080228 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1195972 Terf2 enables GO:0042803 PMID:9326950 IPI UniProtKB:O35144 F telomeric repeat binding factor 2 TRF2 protein taxon:10090 20081216 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1201414 Cer1 enables GO:0042803 PMID:10748465 IDA F cerberus 1, DAN family BMP antagonist Cerberus-like|Cerl|Cerl1|Cerr1|cer-1 protein taxon:10090 20120213 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1270845 Cidea enables GO:0042803 PMID:17080483 IDA F cell death-inducing DNA fragmentation factor, alpha subunit-like effector A protein taxon:10090 20071212 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1277234 Tbx15 enables GO:0042803 PMID:17584735 IPI UniProtKB:O70306 F T-box 15 Tbx14|Tbx8|de protein taxon:10090 20191030 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1316652 Prmt2 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:P55345 F protein arginine N-methyltransferase 2 Hrmt1l1 protein taxon:10090 20110403 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1339753 Csf1 enables GO:0042803 PMID:19017797 IPI UniProtKB:P07141 F colony stimulating factor 1 (macrophage) BAP025|CSF-1|Csfm|M-CSF|colony-stimulating factor-1 protein taxon:10090 20100311 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1339758 Csf1r enables GO:0042803 PMID:19017797 IPI UniProtKB:P09581 F colony stimulating factor 1 receptor CD115|CSF-1R|Csfmr|Fim-2|Fim2|Fms|M-CSFR protein taxon:10090 20090115 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1351322 Mixl1 enables GO:0042803 PMID:22164283 IPI UniProtKB:Q9WUI0 F Mix paired-like homeobox Mml protein taxon:10090 20121029 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1859544 Syt6 enables GO:0042803 PMID:10531343 IDA F synaptotagmin VI 3110037A08Rik protein taxon:10090 20110630 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1859546 Syt10 enables GO:0042803 PMID:10531343 IDA F synaptotagmin X protein taxon:10090 20110630 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1915050 Dgat2 enables GO:0042803 PMID:21680734 IPI UniProtKB:Q9DCV3 F diacylglycerol O-acyltransferase 2 0610010B06Rik protein taxon:10090 20111130 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1923615 Tbx18 enables GO:0042803 PMID:17584735 IPI UniProtKB:Q9EPZ6 F T-box18 2810012F10Rik|2810404D13Rik protein taxon:10090 20191030 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:1930704 Bhlhe41 enables GO:0042803 PMID:17487425 IPI UniProtKB:Q99PV5 F basic helix-loop-helix family, member e41 6430520M22Rik|Bhlhb3|DEC2|Sharp1 protein taxon:10090 20111216 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:2149946 Gopc enables GO:0042803 PMID:11520064 IPI UniProtKB:Q8BH60 F golgi associated PDZ and coiled-coil motif containing 2210402P09Rik|GOPC1 protein taxon:10090 20110330 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:2180781 Slc8b1 enables GO:0042803 PMID:20018762 IPI UniProtKB:Q925Q3 F solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 NCKX6|NCLX|Slc24a6 protein taxon:10090 20140904 BHF-UCL occurs_in(UBERON:0000948)|occurs_in(UBERON:0000955) `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:2442682 Slc30a8 enables GO:0042803 PMID:19095428 IPI UniProtKB:Q8BGG0 F solute carrier family 30 (zinc transporter), member 8 C820002P14Rik|ZnT-8|ZnT8 protein taxon:10090 20100128 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:95392 Eng enables GO:0042803 PMID:8194490 IPI UniProtKB:Q63961 F endoglin CD105|Endo protein taxon:10090 20081107 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:97361 Nos2 enables GO:0042803 PMID:9271491 IDA F nitric oxide synthase 2, inducible NOS-II|Nos-2|Nos2a|iNOS protein taxon:10090 20080725 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:98262 Ccl5 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:P13501 F C-C motif chemokine ligand 5 MuRantes|RANTES|SISd|Scya5|TCP228 protein taxon:10090 20240316 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`MGI MGI:99665 Syt3 enables GO:0042803 PMID:10531343 IDA F synaptotagmin III protein taxon:10090 20110630 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 1565818 Slc8b1 enables GO:0042803 PMID:20018762 IPI UniProtKB:Q6AXS0 F solute carrier family 8 member B1 protein taxon:10116 20140904 BHF-UCL occurs_in(UBERON:0000948) `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 2276 Casq2 enables GO:0042803 PMID:20353949 IDA F calsequestrin 2 protein taxon:10116 20120620 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`RGD 61916 Fzd1 enables GO:0042803 PMID:14688793 IPI UniProtKB:Q08463 F frizzled class receptor 1 protein taxon:10116 20100803 BHF-UCL `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O14503 BHLHE40 enables GO:0042803 PMID:15560782 IDA F Class E basic helix-loop-helix protein 40 BHLHE40|BHLHB2|DEC1|SHARP2|STRA13 protein taxon:9606 20111114 BHF-UCL UniProtKB:O14503 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O14746 TERT enables GO:0042803 PMID:11432839 IDA F Telomerase reverse transcriptase TERT|EST2|TCS1|TRT protein taxon:9606 20081219 BHF-UCL UniProtKB:O14746 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O14958 CASQ2 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:P51868 F Calsequestrin-2 CASQ2 protein taxon:9606 20120620 BHF-UCL UniProtKB:O14958 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O43353 RIPK2 enables GO:0042803 PMID:19337385 IDA F Receptor-interacting serine/threonine-protein kinase 2 RIPK2|CARDIAK|RICK|RIP2|UNQ277/PRO314/PRO34092 protein taxon:9606 20110124 BHF-UCL UniProtKB:O43353 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O60543 CIDEA enables GO:0042803 PMID:17080483 ISS UniProtKB:O70302 F Lipid transferase CIDEA CIDEA protein taxon:9606 20071212 BHF-UCL UniProtKB:O60543 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O95813 CER1 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:O55233 F Cerberus CER1|DAND4 protein taxon:9606 20120213 BHF-UCL UniProtKB:O95813 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB O95935 TBX18 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:Q9EPZ6 F T-box transcription factor TBX18 TBX18 protein taxon:9606 20191030 BHF-UCL UniProtKB:O95935 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P01127 PDGFB enables GO:0042803 PMID:2836953 IDA F Platelet-derived growth factor subunit B PDGFB|PDGF2|SIS protein taxon:9606 20080428 BHF-UCL UniProtKB:P01127 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P02652 APOA2 enables GO:0042803 PMID:17264082 IDA F Apolipoprotein A-II APOA2 protein taxon:9606 20080104 BHF-UCL UniProtKB:P02652 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P04085 PDGFA enables GO:0042803 PMID:2836953 IDA F Platelet-derived growth factor subunit A PDGFA|PDGF1 protein taxon:9606 20080428 BHF-UCL UniProtKB:P04085 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P04085 PDGFA enables GO:0042803 PMID:3754619 IDA F Platelet-derived growth factor subunit A PDGFA|PDGF1 protein taxon:9606 20080428 BHF-UCL UniProtKB:P04085 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P06727 APOA4 enables GO:0042803 PMID:1935934 IDA F Apolipoprotein A-IV APOA4 protein taxon:9606 20080107 BHF-UCL UniProtKB:P06727 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P07333 CSF1R enables GO:0042803 PMID:19017797 ISS UniProtKB:P09581 F Macrophage colony-stimulating factor 1 receptor CSF1R|FMS protein taxon:9606 20090115 BHF-UCL UniProtKB:P07333 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P08567 PLEK enables GO:0042803 PMID:8694752 IDA F Pleckstrin PLEK|P47 protein taxon:9606 20090305 BHF-UCL UniProtKB:P08567 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P08913 ADRA2A enables GO:0042803 PMID:16605244 IDA F Alpha-2A adrenergic receptor ADRA2A|ADRA2R|ADRAR protein taxon:9606 20100630 BHF-UCL UniProtKB:P08913 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P09603 CSF1 enables GO:0042803 PMID:3264878 IDA F Macrophage colony-stimulating factor 1 CSF1 protein taxon:9606 20090115 BHF-UCL UniProtKB:P09603 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P10912 GHR enables GO:0042803 PMID:1549776 IDA F Growth hormone receptor GHR protein taxon:9606 20081205 BHF-UCL UniProtKB:P10912 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P10912 GHR enables GO:0042803 PMID:8137822 IDA F Growth hormone receptor GHR protein taxon:9606 20081205 BHF-UCL UniProtKB:P10912 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P14923 JUP enables GO:0042803 GO_REF:0000024 ISS UniProtKB:Q8SPJ1 F Junction plakoglobin JUP|CTNNG|DP3 protein taxon:9606 20100203 BHF-UCL UniProtKB:P14923 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P15692 VEGFA enables GO:0042803 GO_REF:0000024 ISS UniProtKB:P15691 F Vascular endothelial growth factor A, long form VEGFA|VEGF protein taxon:9606 20080731 BHF-UCL UniProtKB:P15692 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P16234 PDGFRA enables GO:0042803 PMID:2542288 IDA F Platelet-derived growth factor receptor alpha PDGFRA|PDGFR2|RHEPDGFRA protein taxon:9606 20080429 BHF-UCL UniProtKB:P16234 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P17813 ENG enables GO:0042803 PMID:8370410 IPI UniProtKB:P17813-2 F Endoglin ENG|END protein taxon:9606 20081109 BHF-UCL UniProtKB:P17813-2 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P18825 ADRA2C enables GO:0042803 PMID:16605244 IDA F Alpha-2C adrenergic receptor ADRA2C|ADRA2L2|ADRA2RL2 protein taxon:9606 20100630 BHF-UCL UniProtKB:P18825 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P21333 FLNA enables GO:0042803 PMID:2391361 IDA F Filamin-A FLNA|FLN|FLN1 protein taxon:9606 20080914 BHF-UCL UniProtKB:P21333 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P22413 ENPP1 enables GO:0042803 PMID:7830796 IDA F Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1|M6S1|NPPS|PC1|PDNP1 protein taxon:9606 20080225 BHF-UCL UniProtKB:P22413 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P23497 SP100 enables GO:0042803 PMID:9636146 IPI UniProtKB:P23497-1 F Nuclear autoantigen Sp-100 SP100 protein taxon:9606 20100311 BHF-UCL UniProtKB:P23497-1 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P23497 SP100 enables GO:0042803 PMID:9636146 IPI UniProtKB:P23497-2 F Nuclear autoantigen Sp-100 SP100 protein taxon:9606 20081022 BHF-UCL UniProtKB:P23497-2 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P35228 NOS2 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:P29477 F Nitric oxide synthase, inducible NOS2|NOS2A protein taxon:9606 20080725 BHF-UCL UniProtKB:P35228 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P36894 BMPR1A enables GO:0042803 PMID:18436533 IDA F Bone morphogenetic protein receptor type-1A BMPR1A|ACVRLK3|ALK3 protein taxon:9606 20080613 BHF-UCL UniProtKB:P36894 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P41235 HNF4A enables GO:0042803 PMID:12220494 IDA F Hepatocyte nuclear factor 4-alpha HNF4A|HNF4|NR2A1|TCF14 protein taxon:9606 20080421 BHF-UCL UniProtKB:P41235 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P45844 ABCG1 enables GO:0042803 PMID:16870176 IDA F ATP-binding cassette sub-family G member 1 ABCG1|ABC8|WHT1 protein taxon:9606 20071206 BHF-UCL UniProtKB:P45844 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P47992 XCL1 enables GO:0042803 PMID:11889129 IDA F Lymphotactin XCL1|LTN|SCYC1 protein taxon:9606 20110315 BHF-UCL UniProtKB:P47992 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P61296 HAND2 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:Q61039 F Heart- and neural crest derivatives-expressed protein 2 HAND2|BHLHA26|DHAND protein taxon:9606 20090827 BHF-UCL UniProtKB:P61296 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P63316 TNNC1 enables GO:0042803 PMID:18092822 IDA F Troponin C, slow skeletal and cardiac muscles TNNC1|TNNC protein taxon:9606 20080512 BHF-UCL UniProtKB:P63316 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q04771 ACVR1 enables GO:0042803 PMID:18436533 IDA F Activin receptor type-1 ACVR1|ACVRLK2 protein taxon:9606 20080613 BHF-UCL UniProtKB:Q04771 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q13253 NOG enables GO:0042803 PMID:11562478 IDA F Noggin NOG protein taxon:9606 20080711 BHF-UCL UniProtKB:Q13253 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q13563 PKD2 enables GO:0042803 PMID:9192675 IDA F Polycystin-2 PKD2|TRPP1|TRPP2 protein taxon:9606 20120112 BHF-UCL UniProtKB:Q13563 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q16394 EXT1 enables GO:0042803 PMID:12907669 IDA F Exostosin-1 EXT1 protein taxon:9606 20080228 BHF-UCL UniProtKB:Q16394 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q5T7P8 SYT6 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:Q9R0N8 F Synaptotagmin-6 SYT6 protein taxon:9606 20110630 BHF-UCL UniProtKB:Q5T7P8 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q6UB35 MTHFD1L enables GO:0042803 PMID:16171773 IDA F Monofunctional C1-tetrahydrofolate synthase, mitochondrial MTHFD1L|FTHFSDC1 protein taxon:9606 20090720 BHF-UCL UniProtKB:Q6UB35 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q86XE5 HOGA1 enables GO:0042803 PMID:21998747 IDA F 4-hydroxy-2-oxoglutarate aldolase, mitochondrial HOGA1|C10orf65|DHDPSL protein taxon:9606 20120710 BHF-UCL UniProtKB:Q86XE5 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q8IW40 DNAAF19 enables GO:0042803 PMID:22581229 IDA F Dynein axonemal assembly factor 19 DNAAF19|CCDC103 protein taxon:9606 20120726 BHF-UCL occurs_in(CL:0002368) UniProtKB:Q8IW40 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q8IWU4 SLC30A8 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:Q8BGG0 F Proton-coupled zinc antiporter SLC30A8 SLC30A8|ZNT8 protein taxon:9606 20100128 BHF-UCL UniProtKB:Q8IWU4 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q8WYQ5 DGCR8 enables GO:0042803 PMID:15574589 IDA F Microprocessor complex subunit DGCR8 DGCR8|C22orf12|DGCRK6|LP4941 protein taxon:9606 20150115 BHF-UCL UniProtKB:Q8WYQ5 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q92600 CNOT9 enables GO:0042803 PMID:24768540 IDA F CCR4-NOT transcription complex subunit 9 CNOT9|RCD1|RQCD1 protein taxon:9606 20141222 BHF-UCL UniProtKB:Q92600 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q92692 NECTIN2 enables GO:0042803 PMID:9845526 IPI UniProtKB:Q92692-1 F Nectin-2 NECTIN2|HVEB|PRR2|PVRL2 protein taxon:9606 20081128 BHF-UCL UniProtKB:Q92692-1 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q92692 NECTIN2 enables GO:0042803 PMID:9845526 IPI UniProtKB:Q92692-2 F Nectin-2 NECTIN2|HVEB|PRR2|PVRL2 protein taxon:9606 20081128 BHF-UCL UniProtKB:Q92692-2 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q93063 EXT2 NOT|enables GO:0042803 PMID:12907669 IDA F Exostosin-2 EXT2 protein taxon:9606 20080228 BHF-UCL UniProtKB:Q93063 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q96BF6 NACC2 enables GO:0042803 PMID:22926524 IDA F Nucleus accumbens-associated protein 2 NACC2|BTBD14A|NAC2|RBB protein taxon:9606 20121129 BHF-UCL UniProtKB:Q96BF6 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q96PD7 DGAT2 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:Q9DCV3 F Diacylglycerol O-acyltransferase 2 DGAT2|HMFN1045|UNQ738/PRO1433 protein taxon:9606 20111130 BHF-UCL UniProtKB:Q96PD7 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q99697 PITX2 enables GO:0042803 PMID:12612071 IPI UniProtKB:Q99697-3 F Pituitary homeobox 2 PITX2|ARP1|RGS|RIEG|RIEG1 protein taxon:9606 20110922 BHF-UCL UniProtKB:Q99697-3 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q99697 PITX2 enables GO:0042803 PMID:19174163 IPI UniProtKB:Q99697-2 F Pituitary homeobox 2 PITX2|ARP1|RGS|RIEG|RIEG1 protein taxon:9606 20111012 BHF-UCL UniProtKB:Q99697-2 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9C0J9 BHLHE41 enables GO:0042803 GO_REF:0000024 ISS UniProtKB:Q99PV5 F Class E basic helix-loop-helix protein 41 BHLHE41|BHLHB3|DEC2|SHARP1 protein taxon:9606 20111216 BHF-UCL UniProtKB:Q9C0J9 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9H172 ABCG4 enables GO:0042803 PMID:16870176 IDA F ATP-binding cassette sub-family G member 4 ABCG4|WHITE2 protein taxon:9606 20071206 BHF-UCL UniProtKB:Q9H172 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9H2W2 MIXL1 enables GO:0042803 PMID:22164283 ISS UniProtKB:Q9WUI0 F Homeobox protein MIXL1 MIXL1|MIXL protein taxon:9606 20121106 BHF-UCL UniProtKB:Q9H2W2 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9H816 DCLRE1B enables GO:0042803 PMID:20479256 IDA F 5' exonuclease Apollo DCLRE1B|SNM1B protein taxon:9606 20161212 BHF-UCL UniProtKB:Q9H816 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9NP71 MLXIPL NOT|enables GO:0042803 PMID:11230181 IDA F Carbohydrate-responsive element-binding protein MLXIPL|BHLHD14|MIO|WBSCR14 protein taxon:9606 20080307 BHF-UCL UniProtKB:Q9NP71 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9NRR4 DROSHA enables GO:0042803 PMID:15574589 IDA F Ribonuclease 3 DROSHA|RN3|RNASE3L|RNASEN protein taxon:9606 20150115 BHF-UCL UniProtKB:Q9NRR4 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9UNQ0 ABCG2 enables GO:0042803 PMID:16870176 IDA F Broad substrate specificity ATP-binding cassette transporter ABCG2 ABCG2|ABCP|BCRP|BCRP1|MXR protein taxon:9606 20071206 BHF-UCL UniProtKB:Q9UNQ0 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB Q9Y2Z4 YARS2 enables GO:0042803 PMID:15779907 IPI UniProtKB:Q6PI48 F Tyrosine--tRNA ligase, mitochondrial YARS2|CGI-04 protein taxon:9606 20110718 BHF-UCL UniProtKB:Q9Y2Z4 `
WARNING - Violates GO Rule:GORULE:0000046: The ‘with’ field (GAF column 8) must be the same as the gene product (GAF colummn 2) when annotating to ‘self-binding’ terms--`UniProtKB P15691 VEGFA enables GO:0042803 PMID:2798412 IDA F Vascular endothelial growth factor A VEGFA|VEGF protein taxon:9913 20080731 BHF-UCL UniProtKB:P15691 `

gorule-0000061

Allowed gene product to term relations (gp2term)

total: 5

messages

WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0001025, RO:0002432. Repaired to RO:0001025--`UniProtKB O60716 CTNND1 part_of GO:0005912 PMID:20123964 IDA C Catenin delta-1 CTNND1|KIAA0384 protein taxon:9606 20241217 BHF-UCL part_of(CL:0000115) UniProtKB:O60716 `
WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0001025 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB P25686 DNAJB2 located_in GO:0000502 PMID:15936278 IDA C DnaJ homolog subfamily B member 2 DNAJB2|HSJ1|HSPF3 protein taxon:9606 20231121 BHF-UCL UniProtKB:P25686-2 `
WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0001025, RO:0002432. Repaired to RO:0001025--`UniProtKB P35222 CTNNB1 part_of GO:0005829 PMID:20123964 IDA C Catenin beta-1 CTNNB1|CTNNB|OK/SW-cl.35|PRO2286 protein taxon:9606 20241217 BHF-UCL part_of(CL:0000115) UniProtKB:P35222 `
WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: BFO:0000050 should be one of RO:0002325, RO:0001025, RO:0002432. Repaired to RO:0001025--`UniProtKB Q15848 ADIPOQ part_of GO:0005576 PMID:11222466 IDA C Adiponectin ADIPOQ|ACDC|ACRP30|APM1|GBP28 protein taxon:9606 20241115 BHF-UCL UniProtKB:Q15848 `
WARNING - Violates GO Rule:GORULE:0000061: Found violation of: `Only certain gene product to term relations are allowed for a given GO term` but was repaired: RO:0002432 should be one of BFO:0000050. Repaired to BFO:0000050--`UniProtKB Q7KZN9 COX15 is_active_in GO:0070069 PMID:12474143 IDA C Heme A synthase COX15 COX15 protein taxon:9606 20240209 BHF-UCL UniProtKB:Q7KZN9 `

GORULE violations assigned by BHF-UCL

Contents

MESSAGES

gorule-0000001

messages

gorule-0000005

messages

gorule-0000013

messages

gorule-0000015

messages

gorule-0000016

messages

gorule-0000020

messages

gorule-0000027

messages

gorule-0000039

messages

gorule-0000046

messages

gorule-0000061

messages