Overview

The gene association files ingested from GO Consortium members are shown in the table below. Files are in the GO annotation file format and are compressed using the UNIX gzip utility. Please see the upstream resource information for further details on the annotation set. Any errors or omissions in annotations should be reported by writing to the GO Helpdesk.


Filtered Files

These files are taxon-specific and reflect the work of specific projects, primarily the model organisms database groups, to provide comprehensive, non-redundant annotation files for their organism. All the files in this table have been filtered using the annotation file QC pipeline. A major component to the filtering is the requirement that particular taxon IDs can only be included within the association files provided by specific projects; the current list of authoritative groups and major model organisms can be found below.


Filtered Annotation File Downloads for 2025-09-14 release

Species/Database Entity type Annotations File
Species/Database Entity type Annotations File
Dictyostelium discoideum
dictyBase (dictyBase)
n/a 78167 dictybase.gaf (gzip)
Mus musculus
Mouse Genome Informatics (mgi)
n/a 743338 mgi.gaf (gzip)
Solanaceae
Sol Genomics Network (sgn)
gene 1354 sgn.gaf (gzip)
Sus scrofa
EBI Gene Ontology Annotation Database (goa)
all 306730 goa_pig.gaf (gzip)
Danio rerio
Zebrafish Information Network (zfin)
n/a 250666 zfin.gaf (gzip)
Escherichia coli
Encyclopedia of E. coli metabolism (ecocyc)
n/a 62536 ecocyc.gaf (gzip)
Rattus norvegicus
Rat Genome Database (rgd)
n/a 598354 rgd.gaf (gzip)
Saccharomyces cerevisiae
Saccharomyces Genome Database (sgd)
n/a 144519 sgd.gaf (gzip)
Schizosaccharomyces pombe
PomBase (pombase)
n/a 56488 pombase.gaf (gzip)
Plasmodium falciparum
GeneDB (genedb)
n/a 10449 genedb_pfalciparum.gaf (gzip)
Pseudomonas aeruginosa
Pseudomonas Genome Project (pseudocap)
n/a 30006 pseudocap.gaf (gzip)
Drosophila melanogaster
FlyBase (fb)
n/a 188508 fb.gaf (gzip)
Homo sapiens
EBI Gene Ontology Annotation Database (goa)
all 980407 goa_human.gaf (gzip)
Caenorhabditis elegans
WormBase database of nematode biology (wb)
n/a 127000 wb.gaf (gzip)
Bos taurus
EBI Gene Ontology Annotation Database (goa)
all 301007 goa_cow.gaf (gzip)
Leishmania major
GeneDB (genedb)
n/a 9843 genedb_lmajor.gaf (gzip)
Xenopus
Xenbase (tropicalis) (xenbase)
n/a 333955 xenbase.gaf (gzip)
Schizosaccharomyces japonicus
JaponicusDB (japonicusdb)
n/a 15887 japonicusdb.gaf (gzip)
Multi-species
Reactome - a curated knowledgebase of biological pathways (reactome)
n/a 103352 reactome.gaf (gzip)
Multi-species
Candida Genome Database (cgd)
n/a 361731 cgd.gaf (gzip)
Gallus gallus
EBI Gene Ontology Annotation Database (goa)
all 297238 goa_chicken.gaf (gzip)
Canis lupus familiaris
EBI Gene Ontology Annotation Database (goa)
all 266005 goa_dog.gaf (gzip)
Trypanosoma brucei
GeneDB (genedb)
n/a 20191 genedb_tbrucei.gaf (gzip)
Arabidopsis thaliana
The Arabidopsis Information Resource (tair)
n/a 289759 tair.gaf (gzip)

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The Gene Ontology Consortium is funded by the National Human Genome Research Institute (US National Institutes of Health), grant number HG012212, with co-funding by NIGMS.