Overview

The gene association files ingested from GO Consortium members are shown in the table below. Files are in the GO annotation file format and are compressed using the UNIX gzip utility. Please see the upstream resource information for further details on the annotation set. Any errors or omissions in annotations should be reported by writing to the GO Helpdesk.


Filtered Files

These files are taxon-specific and reflect the work of specific projects, primarily the model organisms database groups, to provide comprehensive, non-redundant annotation files for their organism. All the files in this table have been filtered using the annotation file QC pipeline. A major component to the filtering is the requirement that particular taxon IDs can only be included within the association files provided by specific projects; the current list of authoritative groups and major model organisms can be found below.


Filtered Annotation File Downloads for 2025-06-22 release

Species/Database Entity type Annotations File
Species/Database Entity type Annotations File
Dictyostelium discoideum
dictyBase (dictyBase)
n/a 83336 dictybase.gaf (gzip)
Mus musculus
Mouse Genome Informatics (mgi)
n/a 1137927 mgi.gaf (gzip)
Solanaceae
Sol Genomics Network (sgn)
gene 1354 sgn.gaf (gzip)
Sus scrofa
EBI Gene Ontology Annotation Database (goa)
all 327606 goa_pig.gaf (gzip)
Danio rerio
Zebrafish Information Network (zfin)
n/a 260362 zfin.gaf (gzip)
Escherichia coli
Encyclopedia of E. coli metabolism (ecocyc)
n/a 65799 ecocyc.gaf (gzip)
Rattus norvegicus
Rat Genome Database (rgd)
n/a 616456 rgd.gaf (gzip)
Saccharomyces cerevisiae
Saccharomyces Genome Database (sgd)
n/a 151555 sgd.gaf (gzip)
Schizosaccharomyces pombe
PomBase (pombase)
n/a 101473 pombase.gaf (gzip)
Plasmodium falciparum
GeneDB (genedb)
n/a 10674 genedb_pfalciparum.gaf (gzip)
Pseudomonas aeruginosa
Pseudomonas Genome Project (pseudocap)
n/a 32377 pseudocap.gaf (gzip)
Drosophila melanogaster
FlyBase (fb)
n/a 138322 fb.gaf (gzip)
Homo sapiens
EBI Gene Ontology Annotation Database (goa)
all 993459 goa_human.gaf (gzip)
Caenorhabditis elegans
WormBase database of nematode biology (wb)
n/a 138423 wb.gaf (gzip)
Bos taurus
EBI Gene Ontology Annotation Database (goa)
all 340261 goa_cow.gaf (gzip)
Leishmania major
GeneDB (genedb)
n/a 9855 genedb_lmajor.gaf (gzip)
Xenopus tropicalis
Xenbase (tropicalis) (xenbase)
n/a 209319 xenbase.gaf (gzip)
Schizosaccharomyces japonicus
JaponicusDB (japonicusdb)
n/a 15708 japonicusdb.gaf (gzip)
Multi-species
Reactome - a curated knowledgebase of biological pathways (reactome)
n/a 102196 reactome.gaf (gzip)
Xenopus laevis
Xenbase (laevis) (xenbase)
n/a 165869 xenbase_alt.gaf (gzip)
Multi-species
Candida Genome Database (cgd)
n/a 363792 cgd.gaf (gzip)
Gallus gallus
EBI Gene Ontology Annotation Database (goa)
all 323036 goa_chicken.gaf (gzip)
Canis lupus familiaris
EBI Gene Ontology Annotation Database (goa)
all 284789 goa_dog.gaf (gzip)
Trypanosoma brucei
GeneDB (genedb)
n/a 20203 genedb_tbrucei.gaf (gzip)
Arabidopsis thaliana
The Arabidopsis Information Resource (tair)
n/a 228120 tair.gaf (gzip)

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The Gene Ontology Consortium is funded by the National Human Genome Research Institute (US National Institutes of Health), grant number HG012212, with co-funding by NIGMS.