2024-03-16
definition
IAO:0000233
external
term_tracker_item
true
true
term_tracker_item
term tracker item
IAO:0000700
external
has_ontology_root_term
true
true
has_ontology_root_term
has ontology root term
term replaced by
Rhea list of ChEBI terms representing the major species at pH 7.3.
Term not to be used for direct annotation
Term not to be used for direct manual annotation
AGR slim
Aspergillus GO slim
Candida GO slim
ChEMBL protein targets summary
Drosophila GO slim
Insecta GO ribbon slim
Generic GO slim
Metagenomics GO slim
Mouse GO slim
PIR GO slim
Plant GO slim
Fission yeast GO slim
GO subset for prokaryotes
Prokaryote GO ribbon slim
synapse GO slim
Yeast GO slim
label approved by the SynGO project
Systematic synonym
subset_property
synonym_type_property
consider
has_alternative_id
has_broad_synonym
database_cross_reference
has_exact_synonym
has_narrow_synonym
has_obo_format_version
has_obo_namespace
has_related_synonym
has_scope
has_synonym_type
in_subset
shorthand
BFO:0000050
external
part_of
part_of
part of
BFO:0000051
external
has_part
has_part
has part
BFO:0000066
external
occurs_in
occurs_in
occurs in
RO:0002091
external
starts_during
starts_during
starts during
RO:0002092
external
happens_during
happens_during
happens during
RO:0002093
external
ends_during
ends_during
ends during
RO:0002211
external
regulates
regulates
regulates
RO:0002212
external
negatively_regulates
negatively_regulates
negatively regulates
RO:0002213
external
positively_regulates
positively_regulates
positively regulates
The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
GO:0007104
GO:0016288
GO:0033205
Wikipedia:Cytokinesis
cell cycle cytokinesis
cytokinesis involved in cell cycle
biological_process
GO:0000910
Note that this term should not be used for direct annotation. When annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639. Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other.
cytokinesis
The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
GOC:mtg_cell_cycle
cytokinesis involved in cell cycle
GOC:dph
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
response to acid
biological_process
response to acid anion
response to oxoanion
GO:0001101
This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.
response to acid chemical
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
GOC:go_curators
GOC:rn
Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
ciliary/flagellar motility
biological_process
ciliary or bacterial-type flagellar motility
GO:0001539
Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC.
cilium or flagellum-dependent cell motility
Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
GOC:cilia
GOC:hjd
GOC:krc
Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
biological_process
GO:0002831
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to biotic stimulus
Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
GOC:add
Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
down regulation of response to biotic stimulus
down-regulation of response to biotic stimulus
downregulation of response to biotic stimulus
inhibition of response to biotic stimulus
biological_process
GO:0002832
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
negative regulation of response to biotic stimulus
Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
GOC:add
Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
up regulation of response to biotic stimulus
up-regulation of response to biotic stimulus
upregulation of response to biotic stimulus
activation of response to biotic stimulus
stimulation of response to biotic stimulus
biological_process
GO:0002833
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
positive regulation of response to biotic stimulus
Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
GOC:add
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
Wikipedia:Cell_cycle
cell-division cycle
biological_process
GO:0007049
cell cycle
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
GOC:go_curators
GOC:mtg_cell_cycle
The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.
jl
2012-09-20T14:06:08Z
GO:0023032
GO:0044708
GO:0044709
Wikipedia:Behavior
behavioral response to stimulus
behaviour
behavioural response to stimulus
biological_process
single-organism behavior
GO:0007610
1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.
2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).
behavior
The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.
GOC:ems
GOC:jl
ISBN:0395448956
PMID:20160973
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
response to environmental stimulus
biological_process
GO:0009605
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to external stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
response to biotic stress
biological_process
GO:0009607
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to biotic stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.
https://github.com/geneontology/go-ontology/issues/16572
response to abiotic stress
biological_process
GO:0009628
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to abiotic stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.
GOC:hb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
biological_process
GO:0009719
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to endogenous stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GOC:sm
The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
GO:0009795
embryogenesis and morphogenesis
Wikipedia:Embryogenesis
embryogenesis
embryonal development
biological_process
GO:0009790
embryo development
The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
GOC:go_curators
GOC:isa_complete
GOC:mtg_sensu
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
biological_process
response to SSRI
response to selective serotonin reuptake inhibitor
GO:0014076
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.
response to fluoxetine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
GOC:ef
GOC:pr
A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.
https://github.com/geneontology/go-ontology/issues/20935
GO:0072416
Wikipedia:Spindle_checkpoint
signal transduction involved in spindle checkpoint
spindle checkpoint
biological_process
GO:0031577
Note that this term should not be used for direct manual annotation as it should always be possible to choose either a mitotic or meiotic child term.
spindle checkpoint signaling
A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.
GOC:mtg_cell_cycle
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
biological_process
GO:0032101
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to external stimulus
Any process that modulates the frequency, rate or extent of a response to an external stimulus.
GOC:mah
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.
down regulation of response to external stimulus
down-regulation of response to external stimulus
downregulation of response to external stimulus
inhibition of response to external stimulus
biological_process
GO:0032102
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
negative regulation of response to external stimulus
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.
GOC:mah
Any process that activates, maintains or increases the rate of a response to an external stimulus.
up regulation of response to external stimulus
up-regulation of response to external stimulus
upregulation of response to external stimulus
activation of response to external stimulus
stimulation of response to external stimulus
biological_process
GO:0032103
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
positive regulation of response to external stimulus
Any process that activates, maintains or increases the rate of a response to an external stimulus.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
biological_process
GO:0033554
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to stress
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:mah
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.
bf
2012-07-09T01:26:24Z
biological_process
GO:0036270
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to diuretic
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.
bf
2012-07-09T01:30:57Z
response to MPD
response to MPH
response to ritalin
biological_process
GO:0036271
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to methylphenidate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.
GOC:hp
Wikipedia:Methylphenidate
response to MPD
CHEBI:6887
response to MPH
CHEBI:6887
response to ritalin
CHEBI:6887
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.
bf
2012-07-09T01:36:03Z
response to 2',2'-difluorodeoxycytidine
response to 2'-deoxy-2',2'-difluorocytidine
biological_process
GO:0036272
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to gemcitabine
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.
GOC:hp
Wikipedia:Gemcitabine
response to 2',2'-difluorodeoxycytidine
CHEBI:175901
response to 2'-deoxy-2',2'-difluorocytidine
CHEBI:175901
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
bf
2012-07-09T01:54:01Z
biological_process
response to HMG-CoA reductase inhibitor
response to hydroxymethylglutaryl-CoA reductase inhibitor
GO:0036273
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to statin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
GOC:hp
response to HMG-CoA reductase inhibitor
CHEBI:35664
response to hydroxymethylglutaryl-CoA reductase inhibitor
CHEBI:35664
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.
bf
2012-07-09T02:02:26Z
biological_process
GO:0036274
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to lapatinib
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.
bf
2012-07-09T02:08:23Z
response to 5-fluoropyrimidine-2,4(1H,3H)-dione
response to fluorouracil
biological_process
GO:0036275
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to 5-fluorouracil
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.
GOC:hp
response to 5-fluoropyrimidine-2,4(1H,3H)-dione
CHEBI:46345
response to fluorouracil
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.
bf
2012-07-09T02:12:44Z
biological_process
GO:0036276
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to antidepressant
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.
bf
2012-07-09T02:40:12Z
biological_process
GO:0036277
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to anticonvulsant
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.
bf
2012-07-16T05:01:29Z
biological_process
GO:0036287
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to iloperidone
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.
bf
2012-07-16T05:03:56Z
biological_process
GO:0036288
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to ximelagatran
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.
GOC:hp
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
response to chemical stimulus
response to chemical substance
biological_process
GO:0042221
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to chemical
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GOC:jl
response to chemical stimulus
GOC:dos
A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
https://github.com/geneontology/go-ontology/issues/17727
biological_process
GO:0042710
biofilm formation
A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
GOC:di
PMID:11932229
A distinct period or stage in a biological process or cycle.
jl
2014-07-16T13:12:40Z
biological_process
GO:0044848
Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase.
biological phase
A distinct period or stage in a biological process or cycle.
GOC:jl
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
biological_process
GO:0048583
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to stimulus
Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
up regulation of response to stimulus
up-regulation of response to stimulus
upregulation of response to stimulus
activation of response to stimulus
stimulation of response to stimulus
biological_process
GO:0048584
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
positive regulation of response to stimulus
Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
down regulation of response to stimulus
down-regulation of response to stimulus
downregulation of response to stimulus
inhibition of response to stimulus
biological_process
GO:0048585
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
negative regulation of response to stimulus
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GOC:jid
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0051869
physiological response to stimulus
biological_process
GO:0050896
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
response to stimulus
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GOC:ai
GOC:bf
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
transferase regulator
biological_process
GO:0051338
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
regulation of transferase activity
Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
GOC:ai
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
transferase activator
up regulation of transferase activity
up-regulation of transferase activity
upregulation of transferase activity
activation of transferase activity
stimulation of transferase activity
biological_process
GO:0051347
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
positive regulation of transferase activity
Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GOC:ai
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
down regulation of transferase activity
down-regulation of transferase activity
downregulation of transferase activity
transferase inhibitor
inhibition of transferase activity
biological_process
GO:0051348
This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
negative regulation of transferase activity
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
GOC:ai
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
biological_process
GO:0051716
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GOC:bf
GOC:jl
A compound molecular function in which an effector function is controlled by one or more regulatory components.
molecular_function
GO:0060089
molecular transducer activity
A compound molecular function in which an effector function is controlled by one or more regulatory components.
GOC:dos
GOC:pdt
A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.
mah
2009-04-29T12:55:46Z
GO:0090544
BAF-type complex
SWI-SNF-type complex
cellular_component
SWI-SNF global transcription activator complex
SWI/SNF-type complex
SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex
GO:0070603
SWI/SNF superfamily-type complex
A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.
GOC:bhm
GOC:krc
GOC:mah
PMID:16155938
SWI-SNF-type complex
GOC:mah
SWI-SNF global transcription activator complex
CORUM:224
SWI/SNF-type complex
GOC:krc
SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex
GOC:krc
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
mah
2009-08-27T04:41:45Z
biological_process
GO:0070887
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to chemical stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
GOC:mah
A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.
https://github.com/geneontology/go-ontology/issues/20935
mah
2009-11-23T12:36:57Z
GO:0072486
SAC
signal transduction involved in spindle assembly checkpoint
spindle assembly checkpoint
biological_process
GO:0071173
Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle assembly checkpoint (mitotic or meiotic).
spindle assembly checkpoint signaling
A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.
GOC:mah
SAC
GOC:mah
A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.
https://github.com/geneontology/go-ontology/issues/20935
mah
2009-11-23T12:41:36Z
GO:0072477
mitotic cell cycle spindle checkpoint
mitotic spindle checkpoint
signal transduction involved in mitotic cell cycle spindle checkpoint
signal transduction involved in mitotic spindle checkpoint
biological_process
topo II checkpoint
topoisomerase II checkpoint
GO:0071174
Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation checkpoints).
mitotic spindle checkpoint signaling
A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.
GOC:mtg_cell_cycle
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.
mah
2009-12-03T01:02:11Z
cellular response to abiotic stress
biological_process
GO:0071214
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to abiotic stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.
GOC:mah
cellular response to abiotic stress
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
mah
2009-12-03T01:09:08Z
cellular response to biotic stress
biological_process
GO:0071216
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to biotic stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
GOC:mah
cellular response to biotic stress
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
mah
2009-12-03T02:07:23Z
cellular response to acid
biological_process
cellular response to acid anion
cellular response to oxoanion
GO:0071229
This term should be used to describe a response to a specific acid as a chemical. E.g., if a cell were responding to glutamate, then the response would be glutamate-specific; the cell is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0071468 'cellular response to acidic pH' instead.
cellular response to acid chemical
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
GOC:go_curators
GOC:mah
Wikipedia:Acid
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
mah
2009-12-14T03:09:58Z
biological_process
GO:0071411
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.
cellular response to fluoxetine
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
GOC:mah
GOC:pr
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
mah
2009-12-18T02:25:40Z
biological_process
GO:0071495
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to endogenous stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
GOC:mah
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
mah
2009-12-18T02:36:52Z
biological_process
GO:0071496
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular response to external stimulus
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GOC:mah
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
dhl
2009-05-06T04:51:28Z
biological_process
GO:0080134
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
regulation of response to stress
Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GOC:dhl
Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
tb
2010-01-20T10:29:43Z
biological_process
GO:0090231
Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
regulation of spindle checkpoint
Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
tb
2010-01-20T10:29:43Z
spindle checkpoint activation
biological_process
GO:0090232
positive regulation of spindle checkpoint
Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
GOC:ascb_2009
GOC:dph
GOC:tb
spindle checkpoint activation
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
tb
2010-01-20T10:29:43Z
spindle checkpoint silencing
biological_process
GO:0090233
Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
negative regulation of spindle checkpoint
Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
GOC:ascb_2009
GOC:dph
GOC:tb
spindle checkpoint silencing
GOC:ascb_2009
GOC:dph
GOC:tb
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.
pr
2012-08-01T16:13:31Z
response to bronchodilator agent
biological_process
response to broncholytic agent
GO:0097366
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to bronchodilator
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.
GOC:hp
A membrane that is a (regional) part of the plasma membrane.
dos
2014-03-06T11:55:32Z
region of plasma membrane
cellular_component
GO:0098590
Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.
plasma membrane region
A membrane that is a (regional) part of the plasma membrane.
GOC:dos
A protein complex that is part of a mitochondrion.
cellular_component
mitochondrial protein complex
GO:0098798
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
mitochondrial protein-containing complex
A protein complex that is part of a mitochondrion.
GOC:dos
Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.
cellular_component
GO:0098802
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
plasma membrane signaling receptor complex
Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.
GOC:dos
Development of a sorocarp formed by aggregation of cells with different genotypes.
biological_process
GO:0099134
chimeric sorocarp development
Development of a sorocarp formed by aggregation of cells with different genotypes.
PMID:18272966
Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.
biological_process
GO:0099135
chimeric colonial development
Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.
PMID:18272966
Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.
biological_process
GO:0099136
chimeric non-reproductive fruiting body development
Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.
PMID:18272966
The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.
kmv
2018-03-06T15:09:28Z
biological_process
GO:0110100
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
spindle pole body separation
The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.
GOC:vw
Any process that modulates the frequency, rate or extent of cell cycle checkpoint.
jl
2013-03-06T15:10:20Z
GO:2001047
biological_process
regulation of G1/S checkpoint
regulation of G1/S transition checkpoint
GO:1901976
Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
regulation of cell cycle checkpoint
Any process that modulates the frequency, rate or extent of cell cycle checkpoint.
GOC:TermGenie
GOC:mtg_cell_cycle
PMID:23028116
regulation of G1/S checkpoint
GOC:obol
Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.
jl
2013-03-06T15:10:29Z
GO:2001048
down regulation of cell cycle checkpoint
down-regulation of cell cycle checkpoint
downregulation of cell cycle checkpoint
inhibition of cell cycle checkpoint
biological_process
negative regulation of G1/S checkpoint
negative regulation of G1/S transition checkpoint
GO:1901977
Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).
negative regulation of cell cycle checkpoint
Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.
GOC:TermGenie
GOC:mtg_cell_cycle
PMID:23028116
down regulation of cell cycle checkpoint
GOC:TermGenie
down-regulation of cell cycle checkpoint
GOC:TermGenie
downregulation of cell cycle checkpoint
GOC:TermGenie
inhibition of cell cycle checkpoint
GOC:TermGenie
negative regulation of G1/S checkpoint
GOC:obol
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.
dw
2013-12-02T09:34:08Z
biological_process
GO:1902518
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to cyclophosphamide
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.
dw
2013-12-02T09:44:04Z
biological_process
response to docetaxel
GO:1902519
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to docetaxel trihydrate
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.
dw
2013-12-02T09:44:13Z
biological_process
GO:1902520
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to doxorubicin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.
dw
2013-12-02T09:44:22Z
biological_process
GO:1902521
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to etoposide
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.
dw
2013-12-02T09:44:31Z
biological_process
response to epirubicin
GO:1902522
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to 4'-epidoxorubicin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.
GOC:TermGenie
GOC:dw
PMID:23648065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.
hp
2014-09-25T10:58:06Z
biological_process
GO:1903491
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to simvastatin
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.
GOC:TermGenie
GOC:sl
GO_REF:0000071
PMID:23100282
Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.
al
2014-10-01T13:52:57Z
regulation of mitotic cell cycle spindle checkpoint
biological_process
GO:1903504
Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation or Dma1-dependent).
regulation of mitotic spindle checkpoint
Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.
GOC:TermGenie
GO_REF:0000058
PMID:23442800
regulation of mitotic cell cycle spindle checkpoint
GOC:TermGenie
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
dw
2016-04-08T12:36:39Z
biological_process
GO:1905119
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to haloperidol
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
GOC:TermGenie
GOC:dw
GO_REF:0000071
PMID:24751813
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
dw
2016-04-08T12:36:47Z
biological_process
GO:1905120
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
cellular response to haloperidol
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
GOC:TermGenie
GOC:dw
GO_REF:0000071
PMID:24751813
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.
pr
2013-02-22T10:09:44Z
biological_process
GO:1990054
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
response to temozolomide
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.
GOC:hp
BFO:0000062
external
preceded_by
preceded_by
preceded by
BFO:0000063
external
precedes
precedes
precedes
cjm
2012-03-14T10:35:44Z
GOREL:0000040
external
results_in
results_in
This relation is currently used to connect two regulation processes p1 and p2, such that if r1 regulates p1 and r2 regulates p2, and r1 results_in r2 then the regulation of p1 is required for the regulation of p2. For an example of use, see GO:0035958 'regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter'. Note that a precise definition of this relation is under discussion. After it has been formalized it will be added to RO, where it will have a RO ID. Note that the existing identifier and label are subject to change.
results in
GOREL:0001019
external
results_in_division_of
results_in_division_of
use occurs_in
results in division of
GOREL:0002003
external
results_in_distribution_of
results_in_distribution_of
results in distribution of
GOREL:0002004
external
results_in_fission_of
results_in_fission_of
results in fission of
GOREL:0012006
external
results_in_maintenance_of
results_in_maintenance_of
results in maintenance of
RO:0000053
external
bearer_of
bearer_of
bearer of
RO:0000056
external
participates_in
participates_in
participates in
RO:0000057
external
has_participant
has_participant
has participant
RO:0002007
external
bounding_layer_of
bounding_layer_of
bounding layer of
RO:0002008
external
coincident_with
coincident_with
coincident with
RO:0002010
external
regulates_in_other_organism
regulates_in_other_organism
regulates in other organism
RO:0002013
external
has_regulatory_component_activity
has_regulatory_component_activity
has regulatory component activity
RO:0002014
external
has_negative_regulatory_component_activity
has_negative_regulatory_component_activity
has negative regulatory component activity
RO:0002016
external
has_necessary_component_activity
has_necessary_component_activity
has necessary component activity
RO:0002087
external
immediately_preceded_by
immediately_preceded_by
immediately preceded by
RO:0002090
external
immediately_precedes
immediately_precedes
immediately precedes
RO:0002131
external
overlaps
overlaps
overlaps
RO:0002180
external
has_component
has_component
has component
RO:0002215
external
capable_of
capable_of
capable of
RO:0002216
external
capable_of_part_of
capable_of_part_of
capable of part of
RO:0002220
external
adjacent_to
adjacent_to
adjacent to
RO:0002224
external
starts_with
starts_with
starts with
RO:0002230
external
ends_with
ends_with
ends with
RO:0002231
external
has_start_location
has_start_location
has start location
RO:0002232
external
has_end_location
has_end_location
has end location
RO:0002233
external
has_input
has_input
has input
RO:0002234
external
has_output
has_output
has output
RO:0002295
external
results_in_developmental_progression_of
results_in_developmental_progression_of
results in developmental progression of
RO:0002296
external
results_in_development_of
results_in_development_of
results in development of
RO:0002297
external
results_in_formation_of
results_in_formation_of
results in formation of
RO:0002298
external
results_in_morphogenesis_of
results_in_morphogenesis_of
results in morphogenesis of
RO:0002299
external
results_in_maturation_of
results_in_maturation_of
results in maturation of
RO:0002304
external
causally_upstream_of,_positive_effect
causally_upstream_of,_positive_effect
causally upstream of, positive effect
RO:0002305
external
causally_upstream_of,_negative_effect
causally_upstream_of,_negative_effect
causally upstream of, negative effect
RO:0002315
external
results_in_acquisition_of_features_of
results_in_acquisition_of_features_of
results in acquisition of features of
RO:0002332
external
regulates_levels_of
regulates_levels_of
regulates levels of
RO:0002334
external
regulated_by
regulated_by
regulated by
RO:0002335
external
negatively_regulated_by
negatively_regulated_by
negatively regulated by
RO:0002336
external
positively_regulated_by
positively_regulated_by
positively regulated by
RO:0002338
external
has_target_start_location
has_target_start_location
has target start location
RO:0002339
external
has_target_end_location
has_target_end_location
has target end location
RO:0002341
external
results_in_transport_along
results_in_transport_along
results in transport along
RO:0002342
external
results_in_transport_across
results_in_transport_across
results in transport across
RO:0002343
external
results_in_growth_of
results_in_growth_of
results in growth of
RO:0002344
external
results_in_transport_to_from_or_in
results_in_transport_to_from_or_in
results in transport to from or in
RO:0002348
external
results_in_commitment_to
results_in_commitment_to
results in commitment to
RO:0002349
external
results_in_determination_of
results_in_determination_of
results in determination of
RO:0002353
external
output_of
output_of
output of
RO:0002355
external
results_in_structural_organization_of
results_in_structural_organization_of
results in structural organization of
RO:0002356
external
results_in_specification_of
results_in_specification_of
results in specification of
RO:0002404
external
causally_downstream_of
causally_downstream_of
causally downstream of
RO:0002405
external
immediately_causally_downstream_of
immediately_causally_downstream_of
immediately causally downstream of
RO:0002411
external
causally_upstream_of
causally_upstream_of
causally upstream of
RO:0002412
external
immediately_causally_upstream_of
immediately_causally_upstream_of
immediately causally upstream of
RO:0002418
external
causally_upstream_of_or_within
causally_upstream_of_or_within
causally upstream of or within
RO:0002427
external
causally_downstream_of_or_within
causally_downstream_of_or_within
causally downstream of or within
RO:0002505
external
has_intermediate
has_intermediate
has intermediate
RO:0002565
external
results_in_movement_of
results_in_movement_of
results in movement of
RO:0002578
external
directly_regulates
directly_regulates
directly regulates
RO:0002588
external
results_in_assembly_of
results_in_assembly_of
results in assembly of
RO:0002590
external
results_in_disassembly_of
results_in_disassembly_of
results in disassembly of
RO:0002591
external
results_in_remodeling_of
results_in_remodeling_of
results in remodeling of
RO:0002592
external
results_in_organization_of
results_in_organization_of
results in organization of
RO:0002608
external
process_has_causal_agent
process_has_causal_agent
process has causal agent
RO:0002629
external
directly_positively_regulates
directly_positively_regulates
directly positively regulates
RO:0002630
external
directly_negatively_regulates
directly_negatively_regulates
directly negatively regulates
RO:0003000
external
produces
produces
produces
RO:0003001
external
produced_by
produced_by
produced by
RO:0004007
external
has_primary_input_or_output
has_primary_input_or_output
has primary input or output
RO:0004008
external
has_primary_output
has_primary_output
has primary output
RO:0004009
external
has_primary_input
has_primary_input
has primary input
RO:0012001
external
has_small_molecule_activator
has_small_molecule_activator
has small molecule activator
RO:0012003
external
acts_on_population_of
acts_on_population_of
acts on population of
RO:0012008
external
results_in_fusion_of
results_in_fusion_of
results in fusion of
RO:0019000
gene_ontology
regulates_characteristic
regulates_characteristic
regulates characteristic
RO:0019001
gene_ontology
positively_regulates_characteristic
positively_regulates_characteristic
positively regulates characteristic
RO:0019002
gene_ontology
negatively_regulates_characteristic
negatively_regulates_characteristic
negatively regulates characteristic
RO:0040036
external
results_in_changes_to_anatomical_or_cellular_structure
results_in_changes_to_anatomical_or_cellular_structure
results in changes to anatomical or cellular structure